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The map label for this gene is grxC [H]

Identifier: 89052787

GI number: 89052787

Start: 303701

End: 303961

Strand: Direct

Name: grxC [H]

Synonym: Jann_0296

Alternate gene names: 89052787

Gene position: 303701-303961 (Clockwise)

Preceding gene: 89052786

Following gene: 89052788

Centisome position: 7.03

GC content: 61.69

Gene sequence:

>261_bases
ATGGCCATCGTTACGCTCTATACCTCGCCGCTGTGCGGTTTCTGCCACGCTGCCAAGCGGATGCTGACCGACAAGGGCGT
CAGCTATGCCGAGATTGACGTGGCCGCTGATCCGTCCAAACGGCAGGAGATGATGAGCCGCGCCAATGGTCGCCATACCG
TGCCGCAGATTTTCATCGGTGATGCCCATGTGGGCGGGTATGATGACATGGCGGCACTGGAGCGCACGGGCAAGCTGGAC
CCGATGCTCTCGGCGGACTGA

Upstream 100 bases:

>100_bases
CCGGGCCGGTGCCGAAAATGTGTCCGTTTTGGCTCTGGCGCGTGTCGGGGACGATATCTAGATTGGGCGGTATCGGACCC
TTCAGAAAAGCGAATTCTCC

Downstream 100 bases:

>100_bases
CAGGCGCGTCACACTGGCCCAATCCGGGGCTTTCCCCTTGCGTCACGCTGCACTGCGGCGCTTTACTTCCGGCCATGTCG
AAGCACGAAGATCCTCTTTC

Product: glutaredoxin GrxC

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MAIVTLYTSPLCGFCHAAKRMLTDKGVSYAEIDVAADPSKRQEMMSRANGRHTVPQIFIGDAHVGGYDDMAALERTGKLD
PMLSAD

Sequences:

>Translated_86_residues
MAIVTLYTSPLCGFCHAAKRMLTDKGVSYAEIDVAADPSKRQEMMSRANGRHTVPQIFIGDAHVGGYDDMAALERTGKLD
PMLSAD
>Mature_85_residues
AIVTLYTSPLCGFCHAAKRMLTDKGVSYAEIDVAADPSKRQEMMSRANGRHTVPQIFIGDAHVGGYDDMAALERTGKLDP
MLSAD

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=50.6024096385542, Blast_Score=89, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9317; Mature: 9186

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVTLYTSPLCGFCHAAKRMLTDKGVSYAEIDVAADPSKRQEMMSRANGRHTVPQIFIG
CEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEC
DAHVGGYDDMAALERTGKLDPMLSAD
CCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AIVTLYTSPLCGFCHAAKRMLTDKGVSYAEIDVAADPSKRQEMMSRANGRHTVPQIFIG
EEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEC
DAHVGGYDDMAALERTGKLDPMLSAD
CCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]