Click here to switch to the map view.

The map label for this gene is ppiC [C]

Identifier: 89052781

GI number: 89052781

Start: 297976

End: 298881

Strand: Direct

Name: ppiC [C]

Synonym: Jann_0290

Alternate gene names: 89052781

Gene position: 297976-298881 (Clockwise)

Preceding gene: 89052777

Following gene: 89052782

Centisome position: 6.9

GC content: 60.82

Gene sequence:

>906_bases
ATGATAGTCAACGTAAGGCGACCCTGCCCCAAAGGGCGGTGCGCTCCACACAAAGGAAATTCCCTGATGAAGATGCTTTT
CGCTTCCGTGGCCATGGCCGCAGCTCTTGCCGCACCGGCCTTTGCCGATGGCCACGACAGCGCCGAAACGGTGATGGCCA
CCGTGAATGGCCACGACATCACCGTGGGCCACCTGATCGCCATGCGTCAGATGTTGCCTGCCGAATACCAGCAGCTTCCC
GATGAGGTCTTGTTTGAAGGGATGTTGGAGCAGTTGATTCAGCAGCAAGTGCTGGCTGATGTGGCCGAGGCGAACGTGAC
CCGTGAGATGGAGCTGCTTCTGGAGAATGAGCAGCGTGCCCTCATGGCGGCGACCTATATGGACGACATCGCCATGGCCG
AGCTGGGCGAAGAAGAACTGCAAGCCGCCTATGATGAGGCTTATGGCGAGGTGGAGCCCACCGTTGAATACAATGCCGCC
CATATTCTTGTGGAAGGGGAAGAGGACGCGCAGAACCTGCTGACCGCATTGGGTGAAGGTGCAGATTTTGCGGAACTGGC
CGCCGAGAACTCCATCGGCCCGTCGGGTCCCAATGGCGGCGCTCTGGGGTGGTTCACCGAAGGTATGATGGTGCCCGAGT
TTGAAGCGGCCGTGATGGAGCTTGAACCCGGTGAGGTGTCATCCCCGGTGCAGACACAATTTGGCTGGCACGTCGTGTTG
CTGAATGAGACGCGCGAACAGGCTGCCCCCACGCTTGACGATGTGCGCCCCGAGCTGGAAGAGACCATCCGCCGCGGTCG
CGTCGATGCGCGTCTGGAAGAGCTGATGGCCGAGGCCGAAATCGTGCGCCCCGAGACCGAGGTTGACCCCGCCCTGATCC
GCAACCAGGACCTGATCGCGGAGTAG

Upstream 100 bases:

>100_bases
GGGTCCTCGGGTTGTTCGACCCTGCGCAGCAGACTAACTATTGCGCCAACGGTCGAAGCCCCGGGTTGTATAACCCGTAA
GCGAGATAAGGGGCGGCCTG

Downstream 100 bases:

>100_bases
GCCTATCAGGATTGGGGAGAGACGATTGTGACCGAGACCAAAACGGACGGCCCCGCCGTCTCTCCGCTGGCACCTGCCAG
CTTCCCGGACCTTCCCGCTA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIVNVRRPCPKGRCAPHKGNSLMKMLFASVAMAAALAAPAFADGHDSAETVMATVNGHDITVGHLIAMRQMLPAEYQQLP
DEVLFEGMLEQLIQQQVLADVAEANVTREMELLLENEQRALMAATYMDDIAMAELGEEELQAAYDEAYGEVEPTVEYNAA
HILVEGEEDAQNLLTALGEGADFAELAAENSIGPSGPNGGALGWFTEGMMVPEFEAAVMELEPGEVSSPVQTQFGWHVVL
LNETREQAAPTLDDVRPELEETIRRGRVDARLEELMAEAEIVRPETEVDPALIRNQDLIAE

Sequences:

>Translated_301_residues
MIVNVRRPCPKGRCAPHKGNSLMKMLFASVAMAAALAAPAFADGHDSAETVMATVNGHDITVGHLIAMRQMLPAEYQQLP
DEVLFEGMLEQLIQQQVLADVAEANVTREMELLLENEQRALMAATYMDDIAMAELGEEELQAAYDEAYGEVEPTVEYNAA
HILVEGEEDAQNLLTALGEGADFAELAAENSIGPSGPNGGALGWFTEGMMVPEFEAAVMELEPGEVSSPVQTQFGWHVVL
LNETREQAAPTLDDVRPELEETIRRGRVDARLEELMAEAEIVRPETEVDPALIRNQDLIAE
>Mature_301_residues
MIVNVRRPCPKGRCAPHKGNSLMKMLFASVAMAAALAAPAFADGHDSAETVMATVNGHDITVGHLIAMRQMLPAEYQQLP
DEVLFEGMLEQLIQQQVLADVAEANVTREMELLLENEQRALMAATYMDDIAMAELGEEELQAAYDEAYGEVEPTVEYNAA
HILVEGEEDAQNLLTALGEGADFAELAAENSIGPSGPNGGALGWFTEGMMVPEFEAAVMELEPGEVSSPVQTQFGWHVVL
LNETREQAAPTLDDVRPELEETIRRGRVDARLEELMAEAEIVRPETEVDPALIRNQDLIAE

Specific function: Ppiases Accelerate The Folding Of Proteins. It Prefers Amino Acid Residues With Hydrophobic Side Chains Like Leucine And Phenylalanine In The P1 Position Of The Peptides Substrates. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=81, Percent_Identity=46.9135802469136, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 32842; Mature: 32842

Theoretical pI: Translated: 3.89; Mature: 3.89

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVNVRRPCPKGRCAPHKGNSLMKMLFASVAMAAALAAPAFADGHDSAETVMATVNGHDI
CEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEECCCEE
TVGHLIAMRQMLPAEYQQLPDEVLFEGMLEQLIQQQVLADVAEANVTREMELLLENEQRA
HHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LMAATYMDDIAMAELGEEELQAAYDEAYGEVEPTVEYNAAHILVEGEEDAQNLLTALGEG
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECEEEEEEECCHHHHHHHHHHCCC
ADFAELAAENSIGPSGPNGGALGWFTEGMMVPEFEAAVMELEPGEVSSPVQTQFGWHVVL
CCHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHEEECCCCCCCCHHHCCCEEEEE
LNETREQAAPTLDDVRPELEETIRRGRVDARLEELMAEAEIVRPETEVDPALIRNQDLIA
EECCHHHHCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCC
E
C
>Mature Secondary Structure
MIVNVRRPCPKGRCAPHKGNSLMKMLFASVAMAAALAAPAFADGHDSAETVMATVNGHDI
CEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEECCCEE
TVGHLIAMRQMLPAEYQQLPDEVLFEGMLEQLIQQQVLADVAEANVTREMELLLENEQRA
HHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LMAATYMDDIAMAELGEEELQAAYDEAYGEVEPTVEYNAAHILVEGEEDAQNLLTALGEG
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECEEEEEEECCHHHHHHHHHHCCC
ADFAELAAENSIGPSGPNGGALGWFTEGMMVPEFEAAVMELEPGEVSSPVQTQFGWHVVL
CCHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHEEECCCCCCCCHHHCCCEEEEE
LNETREQAAPTLDDVRPELEETIRRGRVDARLEELMAEAEIVRPETEVDPALIRNQDLIA
EECCHHHHCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]