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The map label for this gene is yafC [C]

Identifier: 89052771

GI number: 89052771

Start: 286144

End: 287049

Strand: Direct

Name: yafC [C]

Synonym: Jann_0280

Alternate gene names: 89052771

Gene position: 286144-287049 (Clockwise)

Preceding gene: 89052768

Following gene: 89052775

Centisome position: 6.63

GC content: 60.15

Gene sequence:

>906_bases
ATGGATCGTCTCACAGAAATGGAAGCCTTCGCCACCGTTGTGGATCAAGGCGGCTTCACCGACGCCGCGAAGAAGATGGG
GATTTCCAAATCCGCCGTGTCCAAACACGTCTCTTCGCTGGAGGCCCGTCTGGGTGCGCGGCTGCTGAACCGAACCACAC
GCCGTGTGTCGCCAACGGAAATCGGCCTTGCCTATTATGACCGCGCCCGCCGCGTCCTGAACGATGCCGGAGAGGCCGAT
GCCCTCGTCACCGCCATGCAATCCGCGCCGTCCGGCACGCTGCGCGTCTCTATCGCCACCGATTTCGGGGTGAACCACGT
CTCTCCCATTCTTGGCGAGTTTCTGCATGCCTTTCCCGACATCACCGTGAACATGGTCCTCAACAACCGGTATGTGGAGC
TGATCTCGGAAGGGTTCGATATGGCGATCCGCGTGGGGGAGCTGGAAGACAGTTCGCTGATGGCACGCAAGATCTGCGAG
ACCCAGCGCCGGATGATCGCCGCGCCGTCGTATTTCGAAGAATACGGGCGGCCTGAGCGGATCGATGACCTGAATGAGCA
CAAGCTGCTGCATTACTCCAACTCCAGCGCCGGGAACGTCTGGAAAATCACTGCCCCCTCGGGTGAGTTGCGCCAAGTGC
GCACCGCCGGTTGGCTGACCGTGAATGATGGTCAAAGCCTTCTGAATGCTGCCATCGGAGGGTTGGGCATCGCCTATCTT
CCCAGTTTCCTCTATGCCGAACCGCTTCGTCAGGGCCTATTGGTCGACGCGATGCCGGATCTGCCCACGGATGTTCAAGG
CGTCTATGCCGTCTATCCACCGGGCCGCTACATCCAGCCCAAGGTTCGCTCCTTCATCGATTACCTGGTCGAAGCCTTCC
GCGACAAAGGCCCCGAAGACTGGTGA

Upstream 100 bases:

>100_bases
CGATCCGCGGAATAATCGTGCTTTGGACAAAGCCACATCCCAATTGCGCCCCATTTGACCACCAAACCTGTCCTCATCGA
GTAATAAGGTTTAGGTCGGT

Downstream 100 bases:

>100_bases
TCCCTCCCTCCCTTGCCGCGCTCTTTGGGACGGCCTGCACTTGAAATGACCCAAAGAGCCCACTTCATCCCGGACCTTGC
CTGCGTGCATCGTCCGGGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDRLTEMEAFATVVDQGGFTDAAKKMGISKSAVSKHVSSLEARLGARLLNRTTRRVSPTEIGLAYYDRARRVLNDAGEAD
ALVTAMQSAPSGTLRVSIATDFGVNHVSPILGEFLHAFPDITVNMVLNNRYVELISEGFDMAIRVGELEDSSLMARKICE
TQRRMIAAPSYFEEYGRPERIDDLNEHKLLHYSNSSAGNVWKITAPSGELRQVRTAGWLTVNDGQSLLNAAIGGLGIAYL
PSFLYAEPLRQGLLVDAMPDLPTDVQGVYAVYPPGRYIQPKVRSFIDYLVEAFRDKGPEDW

Sequences:

>Translated_301_residues
MDRLTEMEAFATVVDQGGFTDAAKKMGISKSAVSKHVSSLEARLGARLLNRTTRRVSPTEIGLAYYDRARRVLNDAGEAD
ALVTAMQSAPSGTLRVSIATDFGVNHVSPILGEFLHAFPDITVNMVLNNRYVELISEGFDMAIRVGELEDSSLMARKICE
TQRRMIAAPSYFEEYGRPERIDDLNEHKLLHYSNSSAGNVWKITAPSGELRQVRTAGWLTVNDGQSLLNAAIGGLGIAYL
PSFLYAEPLRQGLLVDAMPDLPTDVQGVYAVYPPGRYIQPKVRSFIDYLVEAFRDKGPEDW
>Mature_301_residues
MDRLTEMEAFATVVDQGGFTDAAKKMGISKSAVSKHVSSLEARLGARLLNRTTRRVSPTEIGLAYYDRARRVLNDAGEAD
ALVTAMQSAPSGTLRVSIATDFGVNHVSPILGEFLHAFPDITVNMVLNNRYVELISEGFDMAIRVGELEDSSLMARKICE
TQRRMIAAPSYFEEYGRPERIDDLNEHKLLHYSNSSAGNVWKITAPSGELRQVRTAGWLTVNDGQSLLNAAIGGLGIAYL
PSFLYAEPLRQGLLVDAMPDLPTDVQGVYAVYPPGRYIQPKVRSFIDYLVEAFRDKGPEDW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=36.4583333333333, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=34.6801346801347, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=31.3131313131313, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=29.8969072164948, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=30.0675675675676, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=26.6666666666667, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=29.1666666666667, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788706, Length=301, Percent_Identity=26.2458471760797, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786448, Length=302, Percent_Identity=23.5099337748344, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789173, Length=287, Percent_Identity=23.3449477351916, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082132, Length=296, Percent_Identity=24.6621621621622, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=22.4137931034483, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790011, Length=262, Percent_Identity=25.1908396946565, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33261; Mature: 33261

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLTEMEAFATVVDQGGFTDAAKKMGISKSAVSKHVSSLEARLGARLLNRTTRRVSPTE
CCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IGLAYYDRARRVLNDAGEADALVTAMQSAPSGTLRVSIATDFGVNHVSPILGEFLHAFPD
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCC
ITVNMVLNNRYVELISEGFDMAIRVGELEDSSLMARKICETQRRMIAAPSYFEEYGRPER
CEEEEEECCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
IDDLNEHKLLHYSNSSAGNVWKITAPSGELRQVRTAGWLTVNDGQSLLNAAIGGLGIAYL
CCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHH
PSFLYAEPLRQGLLVDAMPDLPTDVQGVYAVYPPGRYIQPKVRSFIDYLVEAFRDKGPED
HHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
W
C
>Mature Secondary Structure
MDRLTEMEAFATVVDQGGFTDAAKKMGISKSAVSKHVSSLEARLGARLLNRTTRRVSPTE
CCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IGLAYYDRARRVLNDAGEADALVTAMQSAPSGTLRVSIATDFGVNHVSPILGEFLHAFPD
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCC
ITVNMVLNNRYVELISEGFDMAIRVGELEDSSLMARKICETQRRMIAAPSYFEEYGRPER
CEEEEEECCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
IDDLNEHKLLHYSNSSAGNVWKITAPSGELRQVRTAGWLTVNDGQSLLNAAIGGLGIAYL
CCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHH
PSFLYAEPLRQGLLVDAMPDLPTDVQGVYAVYPPGRYIQPKVRSFIDYLVEAFRDKGPED
HHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]