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The map label for this gene is cynT [H]

Identifier: 89052599

GI number: 89052599

Start: 98574

End: 99224

Strand: Direct

Name: cynT [H]

Synonym: Jann_0108

Alternate gene names: 89052599

Gene position: 98574-99224 (Clockwise)

Preceding gene: 89052595

Following gene: 89052600

Centisome position: 2.28

GC content: 59.75

Gene sequence:

>651_bases
ATGCACCGCGTGAACTCCCTGCCCGATTACCTGCTGGACCGGTACAAGGACTGGAAGGACCAGAGCTTTCCCGAGAACCG
CGACTGGTTCCGCAAACTGGCCGATGAAGGCCAGCATCCACGGGCCATGGTGATTGCCTGCTGCGACAGCCGCGTCGCGA
TCAACTCCGTCTTCGGCCAGCGCACCGGAGAGCTGTTTGTCCACCGCAACATTGCCAATCTGGTGCCGCCCTATACGCCC
GACGGCAATCACCACGGCACCGGGGCGGCGGTCGAATTTGCCGTCAAACATCTTAAAGTCGAACATATTCTGGTGATGGG
CCATTCCAATTGCGGCGGTGTGGCGGGGTGTATTTCAATGTGCGAAGGCACTGCGCCGGAATTTGATCAAGAGGAAAGCC
TGATCGGCCGCTGGCTGGACGTGCTGCGCCCGGGGTATCAGACCGTCTCGGACATCGAAGACCCCAAGGGGCGTCAGACC
GCGCTGGAGAAGGAGGGGATTCATGTCAGCCTGGAGAACCTTCTGGGCTATCCCTTCGTGAAATCCGCCGTGGATGCCGA
AACGCTCAGCCTGCACGGATTATGGGCCGACATCGCGGATATGGATCTGGAGATGTTTGACGGACGGGTCCGCCATTTTA
CACCTGCGTGA

Upstream 100 bases:

>100_bases
CTTGTGCTGAAGAAGAGATTTATCGCGACGGCAAAAGCACCTCCAATTCGATGCGAATGCACGGTATGAGAGGGCAGACT
GACCCGACGAAGGTAGACCG

Downstream 100 bases:

>100_bases
CTGGTTGCGCGCCCCGGCGCGTCGCCGTAGATCCGCGCATCGGTAGCTTAACCCAAGGGAACTTCCATGGACGGAATGCT
GGCACTGGCCGCAGACAACC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MHRVNSLPDYLLDRYKDWKDQSFPENRDWFRKLADEGQHPRAMVIACCDSRVAINSVFGQRTGELFVHRNIANLVPPYTP
DGNHHGTGAAVEFAVKHLKVEHILVMGHSNCGGVAGCISMCEGTAPEFDQEESLIGRWLDVLRPGYQTVSDIEDPKGRQT
ALEKEGIHVSLENLLGYPFVKSAVDAETLSLHGLWADIADMDLEMFDGRVRHFTPA

Sequences:

>Translated_216_residues
MHRVNSLPDYLLDRYKDWKDQSFPENRDWFRKLADEGQHPRAMVIACCDSRVAINSVFGQRTGELFVHRNIANLVPPYTP
DGNHHGTGAAVEFAVKHLKVEHILVMGHSNCGGVAGCISMCEGTAPEFDQEESLIGRWLDVLRPGYQTVSDIEDPKGRQT
ALEKEGIHVSLENLLGYPFVKSAVDAETLSLHGLWADIADMDLEMFDGRVRHFTPA
>Mature_216_residues
MHRVNSLPDYLLDRYKDWKDQSFPENRDWFRKLADEGQHPRAMVIACCDSRVAINSVFGQRTGELFVHRNIANLVPPYTP
DGNHHGTGAAVEFAVKHLKVEHILVMGHSNCGGVAGCISMCEGTAPEFDQEESLIGRWLDVLRPGYQTVSDIEDPKGRQT
ALEKEGIHVSLENLLGYPFVKSAVDAETLSLHGLWADIADMDLEMFDGRVRHFTPA

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=208, Percent_Identity=32.6923076923077, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1786318, Length=219, Percent_Identity=31.9634703196347, Blast_Score=80, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115532990, Length=220, Percent_Identity=25.9090909090909, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324292, Length=184, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24199; Mature: 24199

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRVNSLPDYLLDRYKDWKDQSFPENRDWFRKLADEGQHPRAMVIACCDSRVAINSVFGQ
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCC
RTGELFVHRNIANLVPPYTPDGNHHGTGAAVEFAVKHLKVEHILVMGHSNCGGVAGCISM
CCCCEEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHH
CEGTAPEFDQEESLIGRWLDVLRPGYQTVSDIEDPKGRQTALEKEGIHVSLENLLGYPFV
HCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCCEEEHHHHHCCCHH
KSAVDAETLSLHGLWADIADMDLEMFDGRVRHFTPA
HHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MHRVNSLPDYLLDRYKDWKDQSFPENRDWFRKLADEGQHPRAMVIACCDSRVAINSVFGQ
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCC
RTGELFVHRNIANLVPPYTPDGNHHGTGAAVEFAVKHLKVEHILVMGHSNCGGVAGCISM
CCCCEEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHH
CEGTAPEFDQEESLIGRWLDVLRPGYQTVSDIEDPKGRQTALEKEGIHVSLENLLGYPFV
HCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCCEEEHHHHHCCCHH
KSAVDAETLSLHGLWADIADMDLEMFDGRVRHFTPA
HHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]