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The map label for this gene is lspL [H]

Identifier: 89052568

GI number: 89052568

Start: 70578

End: 71576

Strand: Reverse

Name: lspL [H]

Synonym: Jann_0077

Alternate gene names: 89052568

Gene position: 71576-70578 (Counterclockwise)

Preceding gene: 89052569

Following gene: 89052567

Centisome position: 1.66

GC content: 60.16

Gene sequence:

>999_bases
ATGAGAACAGCATTGGTCACGGGGTCTGCCGGGTTTATCGGCTATCACCTGTGCGCGCGGCTTCTGGCCGACGGCTGGCG
CGTGATCGGTCTGGATGCCATGACCGACTACTATGACGTCTCGCTGAAAGAGGCGCGTCTGGCGATGCTGACGGATCATG
ACGCGTTCACGGGCGTGGAGGCGCGGATCGAAGCGCCGGGCGTCCTGCATGATCTGTTCGATGAGCACCGCCCTGATGCG
ATCATTCACCTCGCCGCCCAGGCAGGCGTGCGGTATTCCATCGAGAACCCCGAGAGTTATGTGGAGGCCAACCTGATCGG
CACCTTCCGCCTGCTGGAGGCGATGCGCGCCTTCCCGCCAAGGCATTCGCTTCTGGCCAGCACCTCGTCGGCCTATGGCG
CAAATACCGAAATGCCCTATGCCGAAACGATGCAGGCCGATCACCAGATGTCGTTCTACGCCGCCACCAAGAAGTCGAAC
GAGGTGATGGCCCATTCCTACGCCCACCTCTACGACCTGCCGACGACGATGTTCCGGTTCTTCACCGTCTATGGCCCCTG
GGGTCGGCCCGATATGGCGCTGTTCAAGTTCACCAAGGCGATCCTCAACGGCGACCCCATCGACGTCTACAATCATGGTG
ACATGAAACGCGACTTCACCTACGTCACCGATCTGGTCGACGGAATTATCCGCCTGATCGAAGCCGTGCCCGGGACGGAG
CCGGTTGAAAGTGACAGCCTGTCCCCCGTTGCGCCGCACCGGATCGTCAACATTGGCAACTCAAACTCTGTTCAGTTGAT
GGACTATATAGAGGCGATTGAAACGGCCACGGGCCGGACCGCCGAAAAGAACATGATGCCGATGCAAGCCGGCGACGTGC
CCGCCACCTGGGCCGATGCCAGCCTGTTGCAGCACCTGACCCAATACACGCCCAGAACCGATATGGCCGAGGGTGTCGCC
AATTTCGTCGCGTGGTATCGCGACTATTACAAGATTTAG

Upstream 100 bases:

>100_bases
GCGGAGGGTCTTGGGCTTCAAACCAATAAGACGCTGGAGGATTTATGTGCCTCTGGCCCCGGGGGTGGGTCTTGGGTCGC
CATAGTAAGGACGTTGAGAG

Downstream 100 bases:

>100_bases
AAGGAGCGCTTTTTCATGCGTATTACGATGATTGGGACGGGCTATGTTGGCCTGGTGTCGGGTGTCTGTTTCTCGGATTT
CGGGCACGACGTGATCTGCG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: UDP-glucuronic acid epimerase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRTALVTGSAGFIGYHLCARLLADGWRVIGLDAMTDYYDVSLKEARLAMLTDHDAFTGVEARIEAPGVLHDLFDEHRPDA
IIHLAAQAGVRYSIENPESYVEANLIGTFRLLEAMRAFPPRHSLLASTSSAYGANTEMPYAETMQADHQMSFYAATKKSN
EVMAHSYAHLYDLPTTMFRFFTVYGPWGRPDMALFKFTKAILNGDPIDVYNHGDMKRDFTYVTDLVDGIIRLIEAVPGTE
PVESDSLSPVAPHRIVNIGNSNSVQLMDYIEAIETATGRTAEKNMMPMQAGDVPATWADASLLQHLTQYTPRTDMAEGVA
NFVAWYRDYYKI

Sequences:

>Translated_332_residues
MRTALVTGSAGFIGYHLCARLLADGWRVIGLDAMTDYYDVSLKEARLAMLTDHDAFTGVEARIEAPGVLHDLFDEHRPDA
IIHLAAQAGVRYSIENPESYVEANLIGTFRLLEAMRAFPPRHSLLASTSSAYGANTEMPYAETMQADHQMSFYAATKKSN
EVMAHSYAHLYDLPTTMFRFFTVYGPWGRPDMALFKFTKAILNGDPIDVYNHGDMKRDFTYVTDLVDGIIRLIEAVPGTE
PVESDSLSPVAPHRIVNIGNSNSVQLMDYIEAIETATGRTAEKNMMPMQAGDVPATWADASLLQHLTQYTPRTDMAEGVA
NFVAWYRDYYKI
>Mature_332_residues
MRTALVTGSAGFIGYHLCARLLADGWRVIGLDAMTDYYDVSLKEARLAMLTDHDAFTGVEARIEAPGVLHDLFDEHRPDA
IIHLAAQAGVRYSIENPESYVEANLIGTFRLLEAMRAFPPRHSLLASTSSAYGANTEMPYAETMQADHQMSFYAATKKSN
EVMAHSYAHLYDLPTTMFRFFTVYGPWGRPDMALFKFTKAILNGDPIDVYNHGDMKRDFTYVTDLVDGIIRLIEAVPGTE
PVESDSLSPVAPHRIVNIGNSNSVQLMDYIEAIETATGRTAEKNMMPMQAGDVPATWADASLLQHLTQYTPRTDMAEGVA
NFVAWYRDYYKI

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=337, Percent_Identity=24.6290801186944, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI42516563, Length=335, Percent_Identity=25.6716417910448, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=25.1445086705202, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=25.1445086705202, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=25.1445086705202, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1786974, Length=319, Percent_Identity=26.9592476489028, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI48994969, Length=286, Percent_Identity=29.3706293706294, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788353, Length=239, Percent_Identity=30.1255230125523, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=25.7225433526012, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=25.5747126436782, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17539532, Length=338, Percent_Identity=27.2189349112426, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17568069, Length=245, Percent_Identity=28.9795918367347, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=324, Percent_Identity=24.3827160493827, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356223, Length=336, Percent_Identity=26.4880952380952, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19923002, Length=325, Percent_Identity=26.1538461538462, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.12 [H]

Molecular weight: Translated: 37040; Mature: 37040

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTALVTGSAGFIGYHLCARLLADGWRVIGLDAMTDYYDVSLKEARLAMLTDHDAFTGVE
CCCEEECCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCHHHHHHHHEEECCCHHCCCC
ARIEAPGVLHDLFDEHRPDAIIHLAAQAGVRYSIENPESYVEANLIGTFRLLEAMRAFPP
EEECCCHHHHHHHHHCCCCCEEEEEHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
RHSLLASTSSAYGANTEMPYAETMQADHQMSFYAATKKSNEVMAHSYAHLYDLPTTMFRF
CHHHHHCCCCCCCCCCCCCHHHHHHHCHHEHEEEECCCCCHHHHHHHHHHHHHHHHHHHH
FTVYGPWGRPDMALFKFTKAILNGDPIDVYNHGDMKRDFTYVTDLVDGIIRLIEAVPGTE
HHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PVESDSLSPVAPHRIVNIGNSNSVQLMDYIEAIETATGRTAEKNMMPMQAGDVPATWADA
CCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHH
SLLQHLTQYTPRTDMAEGVANFVAWYRDYYKI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTALVTGSAGFIGYHLCARLLADGWRVIGLDAMTDYYDVSLKEARLAMLTDHDAFTGVE
CCCEEECCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCHHHHHHHHEEECCCHHCCCC
ARIEAPGVLHDLFDEHRPDAIIHLAAQAGVRYSIENPESYVEANLIGTFRLLEAMRAFPP
EEECCCHHHHHHHHHCCCCCEEEEEHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
RHSLLASTSSAYGANTEMPYAETMQADHQMSFYAATKKSNEVMAHSYAHLYDLPTTMFRF
CHHHHHCCCCCCCCCCCCCHHHHHHHCHHEHEEEECCCCCHHHHHHHHHHHHHHHHHHHH
FTVYGPWGRPDMALFKFTKAILNGDPIDVYNHGDMKRDFTYVTDLVDGIIRLIEAVPGTE
HHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PVESDSLSPVAPHRIVNIGNSNSVQLMDYIEAIETATGRTAEKNMMPMQAGDVPATWADA
CCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHH
SLLQHLTQYTPRTDMAEGVANFVAWYRDYYKI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]