Click here to switch to the map view.

The map label for this gene is rkpK [H]

Identifier: 89052567

GI number: 89052567

Start: 69258

End: 70562

Strand: Reverse

Name: rkpK [H]

Synonym: Jann_0076

Alternate gene names: 89052567

Gene position: 70562-69258 (Counterclockwise)

Preceding gene: 89052568

Following gene: 89052566

Centisome position: 1.63

GC content: 61.84

Gene sequence:

>1305_bases
ATGCGTATTACGATGATTGGGACGGGCTATGTTGGCCTGGTGTCGGGTGTCTGTTTCTCGGATTTCGGGCACGACGTGAT
CTGCGTCGACAAGGACCCTTCGAAGATCGAGATGTTGCAGGCAGGCCAAGTGCCGATCTATGAGCCGGGTCTCGATACGC
TGATGGAAAAGAATGTGGAGGCCGGGCGTCTGTCCTTCACCACGGATTTGGCCAGCGCCGTGGATGGCGCGGAGGCTGTT
TTCATCGCGGTGGGAACGCCGACGCGGCGTGGCGATGGCCATGCCGACCTGACCTATGTGATGGCCGCCGCCGAGGAAGT
CGCCCGCGCGATGACCGGCTACGGCGTCATCGTCACGAAATCCACCGTTCCCGTGGGCACCAACCGCAAGGTCAAACAGG
TCGTCCACAAGGCCGCGCCCGAGCTGGAATTTGATGTGGCCTCCAACCCTGAGTTCCTGCGCGAAGGCGCCGCAATTGAC
GACTTCATGCGCCCCGACCGTGTCGTCGTCGGCGTCCAGTCCGAGCGTGCGGGCGATGTCATGGCCGAGATCTATCGCCC
GCTGTTCCTGCGCGACTTCCCCGTCGTGACCACCGATCTGGAATCGGCAGAGATGATCAAATACGCCGCCAATGCGTTCC
TGGCGACGAAGATCACCTTCATCAATGAAATCGCGGCGCTGTGCGAAAAGGTAGGGGCGGACGTGAAAGAGGTCTCCAAA
GGCATCGGCATGGATGGCCGCATCGGCAACAAGTTCCTGCATGCGGGCCCCGGCTATGGCGGATCCTGCTTCCCCAAAGA
CACCAGCGCGCTGGCCCGCATCGGGCAGGAACATGCGGTGCCCCAAAGCATCGTGGAGACGGTCATTCGCGTGAATGACA
GTGTGAAGGCGCGGATGATCGAGAAGTTGCGCGACCTGTGCGATGGATCGTTCAACGGCAAAGTCATCTCTGTGCTGGGG
GTGACGTTCAAGCCCAACACCGATGACATGCGCGATGCGCCGTCCCTGACGATTGTGCCCGCGTTGGTCGGCGGTGGCGC
GAAGGTGCGCGTCGTGGATCCCCAGGGCCTGCGGGAGGGAGAGGCGCTTCTGCCCGGCGTCAACTGGATGGATGATCCCT
ACAAATCCGTCCAGAACGCCGATCTGGTCGTGCTTCTGACGGAGTGGAACGAATTCCGCGCTCTGGATCTGGAGCGGATC
GCCAAGAAGATGGCCACGCCCCGTCTGGCCGACCTGCGCAATGTCTACAGCCCTCAAGACGCCAAACGTGCGGGCTTTGA
GGCTTATGACGGCGTGGGGCGGTAG

Upstream 100 bases:

>100_bases
CCTGACCCAATACACGCCCAGAACCGATATGGCCGAGGGTGTCGCCAATTTCGTCGCGTGGTATCGCGACTATTACAAGA
TTTAGAAGGAGCGCTTTTTC

Downstream 100 bases:

>100_bases
GTTTTCCATCCCGCCTGACCGCGCCTTCGAACTTTTTCAGAATTATTTTTCCAACCTGATCGGCCAATGAATTATGTCCG
ATCAGGGTGTTTCTGGTGGG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRITMIGTGYVGLVSGVCFSDFGHDVICVDKDPSKIEMLQAGQVPIYEPGLDTLMEKNVEAGRLSFTTDLASAVDGAEAV
FIAVGTPTRRGDGHADLTYVMAAAEEVARAMTGYGVIVTKSTVPVGTNRKVKQVVHKAAPELEFDVASNPEFLREGAAID
DFMRPDRVVVGVQSERAGDVMAEIYRPLFLRDFPVVTTDLESAEMIKYAANAFLATKITFINEIAALCEKVGADVKEVSK
GIGMDGRIGNKFLHAGPGYGGSCFPKDTSALARIGQEHAVPQSIVETVIRVNDSVKARMIEKLRDLCDGSFNGKVISVLG
VTFKPNTDDMRDAPSLTIVPALVGGGAKVRVVDPQGLREGEALLPGVNWMDDPYKSVQNADLVVLLTEWNEFRALDLERI
AKKMATPRLADLRNVYSPQDAKRAGFEAYDGVGR

Sequences:

>Translated_434_residues
MRITMIGTGYVGLVSGVCFSDFGHDVICVDKDPSKIEMLQAGQVPIYEPGLDTLMEKNVEAGRLSFTTDLASAVDGAEAV
FIAVGTPTRRGDGHADLTYVMAAAEEVARAMTGYGVIVTKSTVPVGTNRKVKQVVHKAAPELEFDVASNPEFLREGAAID
DFMRPDRVVVGVQSERAGDVMAEIYRPLFLRDFPVVTTDLESAEMIKYAANAFLATKITFINEIAALCEKVGADVKEVSK
GIGMDGRIGNKFLHAGPGYGGSCFPKDTSALARIGQEHAVPQSIVETVIRVNDSVKARMIEKLRDLCDGSFNGKVISVLG
VTFKPNTDDMRDAPSLTIVPALVGGGAKVRVVDPQGLREGEALLPGVNWMDDPYKSVQNADLVVLLTEWNEFRALDLERI
AKKMATPRLADLRNVYSPQDAKRAGFEAYDGVGR
>Mature_434_residues
MRITMIGTGYVGLVSGVCFSDFGHDVICVDKDPSKIEMLQAGQVPIYEPGLDTLMEKNVEAGRLSFTTDLASAVDGAEAV
FIAVGTPTRRGDGHADLTYVMAAAEEVARAMTGYGVIVTKSTVPVGTNRKVKQVVHKAAPELEFDVASNPEFLREGAAID
DFMRPDRVVVGVQSERAGDVMAEIYRPLFLRDFPVVTTDLESAEMIKYAANAFLATKITFINEIAALCEKVGADVKEVSK
GIGMDGRIGNKFLHAGPGYGGSCFPKDTSALARIGQEHAVPQSIVETVIRVNDSVKARMIEKLRDLCDGSFNGKVISVLG
VTFKPNTDDMRDAPSLTIVPALVGGGAKVRVVDPQGLREGEALLPGVNWMDDPYKSVQNADLVVLLTEWNEFRALDLERI
AKKMATPRLADLRNVYSPQDAKRAGFEAYDGVGR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=435, Percent_Identity=38.8505747126437, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI296040438, Length=333, Percent_Identity=39.6396396396396, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI296040443, Length=281, Percent_Identity=41.2811387900356, Blast_Score=196, Evalue=3e-50,
Organism=Escherichia coli, GI1788340, Length=356, Percent_Identity=29.7752808988764, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI48994968, Length=421, Percent_Identity=27.3159144893112, Blast_Score=152, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17560350, Length=461, Percent_Identity=34.4902386117137, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI17136908, Length=456, Percent_Identity=35.3070175438597, Blast_Score=265, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46847; Mature: 46847

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITMIGTGYVGLVSGVCFSDFGHDVICVDKDPSKIEMLQAGQVPIYEPGLDTLMEKNVE
CEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEECCCHHHHHHCCCC
AGRLSFTTDLASAVDGAEAVFIAVGTPTRRGDGHADLTYVMAAAEEVARAMTGYGVIVTK
CCCEEEHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
STVPVGTNRKVKQVVHKAAPELEFDVASNPEFLREGAAIDDFMRPDRVVVGVQSERAGDV
CCCCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHCCCCHHHHCCCCEEEEEECCCCHHHH
MAEIYRPLFLRDFPVVTTDLESAEMIKYAANAFLATKITFINEIAALCEKVGADVKEVSK
HHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIGMDGRIGNKFLHAGPGYGGSCFPKDTSALARIGQEHAVPQSIVETVIRVNDSVKARMI
CCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
EKLRDLCDGSFNGKVISVLGVTFKPNTDDMRDAPSLTIVPALVGGGAKVRVVDPQGLREG
HHHHHHHCCCCCCEEEEEEEEEECCCCCCHHCCCCEEEEEEEECCCEEEEEECCCCCCCC
EALLPGVNWMDDPYKSVQNADLVVLLTEWNEFRALDLERIAKKMATPRLADLRNVYSPQD
CHHCCCCCCCCCHHHHHCCCCEEEEEECCCCHHCCCHHHHHHHHCCCHHHHHHHHCCCCH
AKRAGFEAYDGVGR
HHHCCCHHHCCCCC
>Mature Secondary Structure
MRITMIGTGYVGLVSGVCFSDFGHDVICVDKDPSKIEMLQAGQVPIYEPGLDTLMEKNVE
CEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEECCCHHHHHHCCCC
AGRLSFTTDLASAVDGAEAVFIAVGTPTRRGDGHADLTYVMAAAEEVARAMTGYGVIVTK
CCCEEEHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
STVPVGTNRKVKQVVHKAAPELEFDVASNPEFLREGAAIDDFMRPDRVVVGVQSERAGDV
CCCCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHCCCCHHHHCCCCEEEEEECCCCHHHH
MAEIYRPLFLRDFPVVTTDLESAEMIKYAANAFLATKITFINEIAALCEKVGADVKEVSK
HHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIGMDGRIGNKFLHAGPGYGGSCFPKDTSALARIGQEHAVPQSIVETVIRVNDSVKARMI
CCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
EKLRDLCDGSFNGKVISVLGVTFKPNTDDMRDAPSLTIVPALVGGGAKVRVVDPQGLREG
HHHHHHHCCCCCCEEEEEEEEEECCCCCCHHCCCCEEEEEEEECCCEEEEEECCCCCCCC
EALLPGVNWMDDPYKSVQNADLVVLLTEWNEFRALDLERIAKKMATPRLADLRNVYSPQD
CHHCCCCCCCCCHHHHHCCCCEEEEEECCCCHHCCCHHHHHHHHCCCHHHHHHHHCCCCH
AKRAGFEAYDGVGR
HHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]