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The map label for this gene is leuE [H]

Identifier: 89052508

GI number: 89052508

Start: 16039

End: 16635

Strand: Reverse

Name: leuE [H]

Synonym: Jann_0017

Alternate gene names: 89052508

Gene position: 16635-16039 (Counterclockwise)

Preceding gene: 89052509

Following gene: 89052506

Centisome position: 0.39

GC content: 62.14

Gene sequence:

>597_bases
ATGATCACCTTATCCCTCGCGCTTATCGTCTTCCTCTTCCCGCTGGCCTATAGCCCCGGTCCCGGCAATCTCTTTTTCGC
GGCGAACGGCGCGCGCTTTGGCGTGCGGGCGACGCTGCCGGCCAATCTGGGCTACCATCTGGCGACCTGGGTTGTGACGC
TCGCCATCGGCTTTGGATTTGCAACCGCGATGGGCCGCGCTCCGATCTTGTTCGACATCATCAAGTGGGTGGGGTCGGGC
TACGTCCTGTATCTGGCCTGGCGCTTCTTTCGGGCGGGGCAGAGCGAGGGCCAGACCGAAGCGCGACCTGCGGGCCTGTT
GGGCGGGGCGGTGTTGCTGCTGACCAACCCAAAAGCCTATTTGATCATCACGGTGATGTTCTCGCAATTTCTGGGACAGT
CCGAGGAACAGAGGATATTGGCTGTCTTCGTCATTGCGACGGTCTTCACGCTCAACAATATGCTGGCATTCACGGCCTGG
ACGATCGCAGGCGACCGGATTGCCACGCGCTTCCGGGATGAGCGGGGCGCGCGGCTGATGAACCGGGGCTTTGCGGCTGT
TCTGGCGGCGGTCGCCGTGTGGATGGTATGGCCGTAA

Upstream 100 bases:

>100_bases
CCTTTGGAAGGGGCAGCTTTGAGCGGCTATGCGCAGGATCCGGGTCGTCAGATGCCAGTCTAGCGTGGGATATTGAGGCC
TCATTGAAGGGTCGTACACC

Downstream 100 bases:

>100_bases
GGGGCGGCTGACTACTGCTTCGGAAAGTAATCCTCGCACCCGCCTTCGCGATACACATCTGCCGTGCAGCAATGCAGCCC
GCCGCCAAACGCGTAGGCAT

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MITLSLALIVFLFPLAYSPGPGNLFFAANGARFGVRATLPANLGYHLATWVVTLAIGFGFATAMGRAPILFDIIKWVGSG
YVLYLAWRFFRAGQSEGQTEARPAGLLGGAVLLLTNPKAYLIITVMFSQFLGQSEEQRILAVFVIATVFTLNNMLAFTAW
TIAGDRIATRFRDERGARLMNRGFAAVLAAVAVWMVWP

Sequences:

>Translated_198_residues
MITLSLALIVFLFPLAYSPGPGNLFFAANGARFGVRATLPANLGYHLATWVVTLAIGFGFATAMGRAPILFDIIKWVGSG
YVLYLAWRFFRAGQSEGQTEARPAGLLGGAVLLLTNPKAYLIITVMFSQFLGQSEEQRILAVFVIATVFTLNNMLAFTAW
TIAGDRIATRFRDERGARLMNRGFAAVLAAVAVWMVWP
>Mature_198_residues
MITLSLALIVFLFPLAYSPGPGNLFFAANGARFGVRATLPANLGYHLATWVVTLAIGFGFATAMGRAPILFDIIKWVGSG
YVLYLAWRFFRAGQSEGQTEARPAGLLGGAVLLLTNPKAYLIITVMFSQFLGQSEEQRILAVFVIATVFTLNNMLAFTAW
TIAGDRIATRFRDERGARLMNRGFAAVLAAVAVWMVWP

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=187, Percent_Identity=28.3422459893048, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI48994979, Length=178, Percent_Identity=21.3483146067416, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21599; Mature: 21599

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLSLALIVFLFPLAYSPGPGNLFFAANGARFGVRATLPANLGYHLATWVVTLAIGFGF
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
ATAMGRAPILFDIIKWVGSGYVLYLAWRFFRAGQSEGQTEARPAGLLGGAVLLLTNPKAY
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEEECCCHH
LIITVMFSQFLGQSEEQRILAVFVIATVFTLNNMLAFTAWTIAGDRIATRFRDERGARLM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NRGFAAVLAAVAVWMVWP
HCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITLSLALIVFLFPLAYSPGPGNLFFAANGARFGVRATLPANLGYHLATWVVTLAIGFGF
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
ATAMGRAPILFDIIKWVGSGYVLYLAWRFFRAGQSEGQTEARPAGLLGGAVLLLTNPKAY
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEEECCCHH
LIITVMFSQFLGQSEEQRILAVFVIATVFTLNNMLAFTAWTIAGDRIATRFRDERGARLM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NRGFAAVLAAVAVWMVWP
HCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]