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The map label for this gene is atpD [H]

Identifier: 88658665

GI number: 88658665

Start: 583023

End: 584546

Strand: Direct

Name: atpD [H]

Synonym: ECH_0573

Alternate gene names: 88658665

Gene position: 583023-584546 (Clockwise)

Preceding gene: 88657687

Following gene: 88657939

Centisome position: 49.57

GC content: 34.91

Gene sequence:

>1524_bases
ATGTCGGGTTTAGCTAGTAAAGCAAAGAGTAGGGTTAAGAGTAGCAAAGGTAAAAATAGCACAAATATTCATGCTGATGA
ATTAAACGAAGATGTTGGAGTAGTAGTTCGTGTTATGACAGCAGTCGTAGATGTAAAGTTTGCTAGTGGTAAAATACCAA
AAATACTTAATGCGTTAGAAAGTAAAGAAATTTATAATGGTAAGAAATTAGTTCTTGAAGTGTCTCAGCATATTAGTGAT
AGTATTGTAAGGTGTATAGCACTTGATGGCACTGATGGTTTGTCTAGAAATGATAAATTTATTGATACTGGTGCTCCTAT
ATCAGTTCCTGTAGGGCGTGGCACATTAGGACGAGTTTTTGATGTACTAGGTAATACAATAGATGAATGTGGCCCGTTAG
AAGAATCAAGTTACTTTATTAAGCAAATATATTCAGAGATTCCTAAGTTAACTGATCAGAAAATTGCAACTGAAATATTG
GTGACTGGTATTAAAGTAATAGATTTACTTGCTCCATACCTTAAAGGTGGAAAAGTTGGATTGTTTGGTGGTGCTGGTGT
AGGTAAAACTGTATTGATTATGGAATTAATACATAATATTGCAAAAGCACATAAAGGAGTATCAGTTTTTGCTGGTGTTG
GGGAACGTACACGTGAAGGGAATGATCTTTATCATGAGATGATAGAATCTGGTGTAATAAATTTAGAAAATAAGGATCAG
TCACAGGCGGTTTTAGTATATGGTCAAATGAATGAACCTCCTGGAGCAAGGTTAAGGGTTGCATTATCAGCTTTAACTAT
GGCTGAATATTTTAGGGATGCTGAAAATCAAGATGTACTATTTTTTGTAGATAATATTTTCAGGTTTACTCAATCTGGAT
CAGAAATTTCAGCTTTGTTAGGGAGAATACCTTCTGCTGTTGGTTATCAGCCAACATTGGCAGCAGAAATGGGTGCAATG
CAAGAAAGAATTACTTCCACTAATAGTGGATCTATTACCTCTGTACAAGCAATATATGTACCAGCAGATGATTTAACAGA
TCCTGCTCCTGCTACTTCTTTTGCACATCTTGATTCAACTACTGTTTTGTCAAGACAAATATCTGAGCTAGGGATATATC
CAGCTGTTGATCCTTTAGATTCAACATCTCAAGCTTTATCTGCTGATGTTGTAGGTAAAGAGCATTATGACGTTGCTAAG
GAAGTACAACGTATATTACAGACATATAAGTCTTTACAAGATATTATTGCAATTCTTGGTATGGATGAACTTTCAGAGGA
AGATAAGCTTATAGTGGCAAGGGCAAGGAAAATTCAAAGGTTTTTATCACAACCTTTTCATGTTGCTGAAGTGTTTACAG
GTGCTCCTGGTAAATTTGTATCTCTTGAAGATACTGTTTTAAGTTTTAAAGGATTGGTAGAAGGTAAATATGATCACTTG
CCTGAAGCTGCATTTTATATGGTTGGTAGTATAGATGATGTCATAAAAAAAGCAGAATTACTTCAAAAGGAAGGTAAAGT
TTAA

Upstream 100 bases:

>100_bases
TTAGTTGTTGCAAGTTTTTTTTATTTTATTACAATACTGGTGAGTTTGGGTAATCGTTAATGGGTTTTTCCCTTGGTGTT
TTTTTATTGTAAGGTATGAG

Downstream 100 bases:

>100_bases
TGAAGTATCTCTCTGTTGAATTTATTACTCCAGATGCTTTTTTAGAGGTAACAAATGTTCTGTCTATTACTTCATATACT
GTAGATGGAGAATTTGTAAT

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSGLASKAKSRVKSSKGKNSTNIHADELNEDVGVVVRVMTAVVDVKFASGKIPKILNALESKEIYNGKKLVLEVSQHISD
SIVRCIALDGTDGLSRNDKFIDTGAPISVPVGRGTLGRVFDVLGNTIDECGPLEESSYFIKQIYSEIPKLTDQKIATEIL
VTGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIMELIHNIAKAHKGVSVFAGVGERTREGNDLYHEMIESGVINLENKDQ
SQAVLVYGQMNEPPGARLRVALSALTMAEYFRDAENQDVLFFVDNIFRFTQSGSEISALLGRIPSAVGYQPTLAAEMGAM
QERITSTNSGSITSVQAIYVPADDLTDPAPATSFAHLDSTTVLSRQISELGIYPAVDPLDSTSQALSADVVGKEHYDVAK
EVQRILQTYKSLQDIIAILGMDELSEEDKLIVARARKIQRFLSQPFHVAEVFTGAPGKFVSLEDTVLSFKGLVEGKYDHL
PEAAFYMVGSIDDVIKKAELLQKEGKV

Sequences:

>Translated_507_residues
MSGLASKAKSRVKSSKGKNSTNIHADELNEDVGVVVRVMTAVVDVKFASGKIPKILNALESKEIYNGKKLVLEVSQHISD
SIVRCIALDGTDGLSRNDKFIDTGAPISVPVGRGTLGRVFDVLGNTIDECGPLEESSYFIKQIYSEIPKLTDQKIATEIL
VTGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIMELIHNIAKAHKGVSVFAGVGERTREGNDLYHEMIESGVINLENKDQ
SQAVLVYGQMNEPPGARLRVALSALTMAEYFRDAENQDVLFFVDNIFRFTQSGSEISALLGRIPSAVGYQPTLAAEMGAM
QERITSTNSGSITSVQAIYVPADDLTDPAPATSFAHLDSTTVLSRQISELGIYPAVDPLDSTSQALSADVVGKEHYDVAK
EVQRILQTYKSLQDIIAILGMDELSEEDKLIVARARKIQRFLSQPFHVAEVFTGAPGKFVSLEDTVLSFKGLVEGKYDHL
PEAAFYMVGSIDDVIKKAELLQKEGKV
>Mature_506_residues
SGLASKAKSRVKSSKGKNSTNIHADELNEDVGVVVRVMTAVVDVKFASGKIPKILNALESKEIYNGKKLVLEVSQHISDS
IVRCIALDGTDGLSRNDKFIDTGAPISVPVGRGTLGRVFDVLGNTIDECGPLEESSYFIKQIYSEIPKLTDQKIATEILV
TGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIMELIHNIAKAHKGVSVFAGVGERTREGNDLYHEMIESGVINLENKDQS
QAVLVYGQMNEPPGARLRVALSALTMAEYFRDAENQDVLFFVDNIFRFTQSGSEISALLGRIPSAVGYQPTLAAEMGAMQ
ERITSTNSGSITSVQAIYVPADDLTDPAPATSFAHLDSTTVLSRQISELGIYPAVDPLDSTSQALSADVVGKEHYDVAKE
VQRILQTYKSLQDIIAILGMDELSEEDKLIVARARKIQRFLSQPFHVAEVFTGAPGKFVSLEDTVLSFKGLVEGKYDHLP
EAAFYMVGSIDDVIKKAELLQKEGKV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=472, Percent_Identity=69.7033898305085, Blast_Score=668, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=318, Percent_Identity=27.0440251572327, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI19913428, Length=403, Percent_Identity=25.3101736972705, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19913426, Length=402, Percent_Identity=24.8756218905473, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI50345984, Length=398, Percent_Identity=24.3718592964824, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4757810, Length=398, Percent_Identity=24.3718592964824, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1790170, Length=470, Percent_Identity=64.8936170212766, Blast_Score=604, Evalue=1e-174,
Organism=Escherichia coli, GI1788251, Length=315, Percent_Identity=29.5238095238095, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790172, Length=307, Percent_Identity=24.7557003257329, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25144756, Length=472, Percent_Identity=69.7033898305085, Blast_Score=669, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=310, Percent_Identity=27.0967741935484, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=391, Percent_Identity=23.2736572890026, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17510931, Length=385, Percent_Identity=23.3766233766234, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988080, Length=372, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=372, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=70.8423326133909, Blast_Score=664, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=385, Percent_Identity=24.1558441558442, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319370, Length=375, Percent_Identity=25.8666666666667, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=257, Percent_Identity=24.5136186770428, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24638766, Length=472, Percent_Identity=69.2796610169492, Blast_Score=661, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=67.515923566879, Blast_Score=637, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583988, Length=311, Percent_Identity=27.3311897106109, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583986, Length=311, Percent_Identity=27.3311897106109, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583984, Length=311, Percent_Identity=27.3311897106109, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583992, Length=421, Percent_Identity=25.6532066508314, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI20129479, Length=308, Percent_Identity=25.6493506493506, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281361666, Length=394, Percent_Identity=24.8730964467005, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24646341, Length=394, Percent_Identity=24.8730964467005, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17136796, Length=394, Percent_Identity=24.8730964467005, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=52.1739130434783, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24658560, Length=405, Percent_Identity=24.6913580246914, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54853; Mature: 54722

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLASKAKSRVKSSKGKNSTNIHADELNEDVGVVVRVMTAVVDVKFASGKIPKILNALE
CCCHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SKEIYNGKKLVLEVSQHISDSIVRCIALDGTDGLSRNDKFIDTGAPISVPVGRGTLGRVF
HHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCEEEECCCCHHHHHH
DVLGNTIDECGPLEESSYFIKQIYSEIPKLTDQKIATEILVTGIKVIDLLAPYLKGGKVG
HHHCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LFGGAGVGKTVLIMELIHNIAKAHKGVSVFAGVGERTREGNDLYHEMIESGVINLENKDQ
EECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCC
SQAVLVYGQMNEPPGARLRVALSALTMAEYFRDAENQDVLFFVDNIFRFTQSGSEISALL
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCHHHHHHH
GRIPSAVGYQPTLAAEMGAMQERITSTNSGSITSVQAIYVPADDLTDPAPATSFAHLDST
HHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHCCHH
TVLSRQISELGIYPAVDPLDSTSQALSADVVGKEHYDVAKEVQRILQTYKSLQDIIAILG
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDELSEEDKLIVARARKIQRFLSQPFHVAEVFTGAPGKFVSLEDTVLSFKGLVEGKYDHL
CHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEHHHHHHHHHHHHCCCHHCC
PEAAFYMVGSIDDVIKKAELLQKEGKV
CHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGLASKAKSRVKSSKGKNSTNIHADELNEDVGVVVRVMTAVVDVKFASGKIPKILNALE
CCHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SKEIYNGKKLVLEVSQHISDSIVRCIALDGTDGLSRNDKFIDTGAPISVPVGRGTLGRVF
HHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCEEEECCCCHHHHHH
DVLGNTIDECGPLEESSYFIKQIYSEIPKLTDQKIATEILVTGIKVIDLLAPYLKGGKVG
HHHCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LFGGAGVGKTVLIMELIHNIAKAHKGVSVFAGVGERTREGNDLYHEMIESGVINLENKDQ
EECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCC
SQAVLVYGQMNEPPGARLRVALSALTMAEYFRDAENQDVLFFVDNIFRFTQSGSEISALL
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCHHHHHHH
GRIPSAVGYQPTLAAEMGAMQERITSTNSGSITSVQAIYVPADDLTDPAPATSFAHLDST
HHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHCCHH
TVLSRQISELGIYPAVDPLDSTSQALSADVVGKEHYDVAKEVQRILQTYKSLQDIIAILG
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDELSEEDKLIVARARKIQRFLSQPFHVAEVFTGAPGKFVSLEDTVLSFKGLVEGKYDHL
CHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEHHHHHHHHHHHHCCCHHCC
PEAAFYMVGSIDDVIKKAELLQKEGKV
CHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA