Click here to switch to the map view.

The map label for this gene is bioD [H]

Identifier: 88658594

GI number: 88658594

Start: 1133993

End: 1134685

Strand: Reverse

Name: bioD [H]

Synonym: ECH_1110

Alternate gene names: 88658594

Gene position: 1134685-1133993 (Counterclockwise)

Preceding gene: 88658187

Following gene: 88658117

Centisome position: 96.47

GC content: 31.02

Gene sequence:

>693_bases
ATGTCAGCTTATTTTATTACATCTTGCGGTACTGATATAGGAAAAACTTTTATTATGACAGCCCTGTGTTGGCATTTAAG
TAAAAGTTATAAGGTAGTACATGCAATAAAACCTGTTATTAGTGGGTGGAGTGATGCGAATATTTTAGATAATGATACAG
GTAAAATACTGTGTAGTTTAAGTATGGATTGTCATGATAGTAATATAACGAAAGTTTCACCTTGGAGGTTGTATTATCCA
CATGCTCCTAATATAGCCGCTAAGTTAGAAAATACTAAATTGGACTATAATAAAATTGTGACATTTTGTTCCCAATGTAT
TAGTCAGGCTCATGATTATTTGTTAATAGAAGGAGTGGGTGGAGTTATGTCTCCTATTACAGATGATAAAACTTGTTTAG
ATATAATACGGGATTTAAATATTAATGTGATTTTGGTTATAGGCTCTTATCTAGGCAGCATAAGTCATACATTAACAGCA
CTGAAAGTGTTGTCTGGTATGTCTGTAAAGGTTGTCCTTACTCTTAAGGATAACAACGTTGTTAATGTTGATGATATAGT
AAAGTTTATTTACGAATATACAGGTAAAACAGTATATATTCAACGCTATGTTACAGGTAGTTTTGATTTATGGAAAGGGA
CATCAGATAATATAGTAAATTTTATAAGTGCAGATAATTATGATAAGTCTTAA

Upstream 100 bases:

>100_bases
TTGCATCTGTCATATTGAATTGCCCTTGTTTCTAAAATATTGTGAACTGGGTTTGTATCAGTTAGGATACGTTTGTTAAA
TTATATTGGTTGTTGTGTAA

Downstream 100 bases:

>100_bases
CCTTTGATTACAAGGTATAGAACTTTGTGTAATGTTTATATTGGTATGATACTTAAGTATTGCAATTTTGAAATGAATTG
TAACGTTATACTTCGCTATG

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSAYFITSCGTDIGKTFIMTALCWHLSKSYKVVHAIKPVISGWSDANILDNDTGKILCSLSMDCHDSNITKVSPWRLYYP
HAPNIAAKLENTKLDYNKIVTFCSQCISQAHDYLLIEGVGGVMSPITDDKTCLDIIRDLNINVILVIGSYLGSISHTLTA
LKVLSGMSVKVVLTLKDNNVVNVDDIVKFIYEYTGKTVYIQRYVTGSFDLWKGTSDNIVNFISADNYDKS

Sequences:

>Translated_230_residues
MSAYFITSCGTDIGKTFIMTALCWHLSKSYKVVHAIKPVISGWSDANILDNDTGKILCSLSMDCHDSNITKVSPWRLYYP
HAPNIAAKLENTKLDYNKIVTFCSQCISQAHDYLLIEGVGGVMSPITDDKTCLDIIRDLNINVILVIGSYLGSISHTLTA
LKVLSGMSVKVVLTLKDNNVVNVDDIVKFIYEYTGKTVYIQRYVTGSFDLWKGTSDNIVNFISADNYDKS
>Mature_229_residues
SAYFITSCGTDIGKTFIMTALCWHLSKSYKVVHAIKPVISGWSDANILDNDTGKILCSLSMDCHDSNITKVSPWRLYYPH
APNIAAKLENTKLDYNKIVTFCSQCISQAHDYLLIEGVGGVMSPITDDKTCLDIIRDLNINVILVIGSYLGSISHTLTAL
KVLSGMSVKVVLTLKDNNVVNVDDIVKFIYEYTGKTVYIQRYVTGSFDLWKGTSDNIVNFISADNYDKS

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=171, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25543; Mature: 25411

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYFITSCGTDIGKTFIMTALCWHLSKSYKVVHAIKPVISGWSDANILDNDTGKILCSL
CCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
SMDCHDSNITKVSPWRLYYPHAPNIAAKLENTKLDYNKIVTFCSQCISQAHDYLLIEGVG
ECCCCCCCCCEECCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCC
GVMSPITDDKTCLDIIRDLNINVILVIGSYLGSISHTLTALKVLSGMSVKVVLTLKDNNV
CCCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCE
VNVDDIVKFIYEYTGKTVYIQRYVTGSFDLWKGTSDNIVNFISADNYDKS
ECHHHHHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SAYFITSCGTDIGKTFIMTALCWHLSKSYKVVHAIKPVISGWSDANILDNDTGKILCSL
CEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
SMDCHDSNITKVSPWRLYYPHAPNIAAKLENTKLDYNKIVTFCSQCISQAHDYLLIEGVG
ECCCCCCCCCEECCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCC
GVMSPITDDKTCLDIIRDLNINVILVIGSYLGSISHTLTALKVLSGMSVKVVLTLKDNNV
CCCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCE
VNVDDIVKFIYEYTGKTVYIQRYVTGSFDLWKGTSDNIVNFISADNYDKS
ECHHHHHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA