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The map label for this gene is rpe [H]

Identifier: 88658377

GI number: 88658377

Start: 74019

End: 74705

Strand: Direct

Name: rpe [H]

Synonym: ECH_0082

Alternate gene names: 88658377

Gene position: 74019-74705 (Clockwise)

Preceding gene: 88657626

Following gene: 88657621

Centisome position: 6.29

GC content: 32.02

Gene sequence:

>687_bases
GTGTTAACGAAAAAAAATAGTTTTAATCGAGGAAAAGTTGTAGAAGTCTCTAGTTCTATATTGTCAGCAGATTTTGCTAA
TTTAGGTAAGTCAGTGGAAATGTTGACAGATGCGGGTGTAGATTATATCCATGTGGATGTGATGGATGGTAATTTTGTGC
CTAATATCACTATAGGACCTGTTGTTGTTTCTGCAATAAAGAAATATACAACCATCCCATTTGATGTGCACCTCATGATT
AATTCTCCTGGTAATTATATAGAGGCTTTTGTTGATGCAGGAGCAGATATGATTACTATTCATGCAGAATCCGATATACA
TTTAGATCGTATAATACAGAAGATTAAGTCTTATAAGAAAAGTGCTGGATTATCTCTTGTTCCAACATCTCACTATAATA
TTTTAGAATATATTATTTTTGAGCTTGATCTTGTGTTGATTATGACAGTAAATCCTGGCTTTGGCGGTCAACAATTTATC
ACATCTCAGTTAGATAAAATTTCATGTGTTCGTAATCTAATAGAAAAATATTCATTGAAAACTAAAATAGCTGTGGATGG
TGGTGTTAATATTAAGAATGCTAAAAGTGTAATTGAAGCTGGTGCAGATATTTTAGTTGTTGGATCTGCAATTTTTAATG
CAAATAACATGTTAGATTATGTACAACAACTTAAGTCCTCTTTCTAG

Upstream 100 bases:

>100_bases
TTTATGAAAAGGATTAAAAATGTTGATTGTTTTTTGCGTACTTGAAAATTATGTGAAATTCAATAGACTGTAAGTTATAT
ATTTCATTATCAAGATTCAC

Downstream 100 bases:

>100_bases
GTTTGTTAGTGAAGTTTTTTGAATGCTGATGTGTATTTTCCTTTTAATGATATTATAGCCTTTTCTTATGTATTTATATG
TAACTGTAATATAGAGTTAA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MLTKKNSFNRGKVVEVSSSILSADFANLGKSVEMLTDAGVDYIHVDVMDGNFVPNITIGPVVVSAIKKYTTIPFDVHLMI
NSPGNYIEAFVDAGADMITIHAESDIHLDRIIQKIKSYKKSAGLSLVPTSHYNILEYIIFELDLVLIMTVNPGFGGQQFI
TSQLDKISCVRNLIEKYSLKTKIAVDGGVNIKNAKSVIEAGADILVVGSAIFNANNMLDYVQQLKSSF

Sequences:

>Translated_228_residues
MLTKKNSFNRGKVVEVSSSILSADFANLGKSVEMLTDAGVDYIHVDVMDGNFVPNITIGPVVVSAIKKYTTIPFDVHLMI
NSPGNYIEAFVDAGADMITIHAESDIHLDRIIQKIKSYKKSAGLSLVPTSHYNILEYIIFELDLVLIMTVNPGFGGQQFI
TSQLDKISCVRNLIEKYSLKTKIAVDGGVNIKNAKSVIEAGADILVVGSAIFNANNMLDYVQQLKSSF
>Mature_228_residues
MLTKKNSFNRGKVVEVSSSILSADFANLGKSVEMLTDAGVDYIHVDVMDGNFVPNITIGPVVVSAIKKYTTIPFDVHLMI
NSPGNYIEAFVDAGADMITIHAESDIHLDRIIQKIKSYKKSAGLSLVPTSHYNILEYIIFELDLVLIMTVNPGFGGQQFI
TSQLDKISCVRNLIEKYSLKTKIAVDGGVNIKNAKSVIEAGADILVVGSAIFNANNMLDYVQQLKSSF

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=215, Percent_Identity=36.2790697674419, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI219879828, Length=215, Percent_Identity=34.4186046511628, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24307923, Length=159, Percent_Identity=28.9308176100629, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789788, Length=214, Percent_Identity=42.5233644859813, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1790523, Length=216, Percent_Identity=36.5740740740741, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=28.436018957346, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17552948, Length=205, Percent_Identity=43.9024390243902, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322341, Length=225, Percent_Identity=32.8888888888889, Blast_Score=150, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=37.7358490566038, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24906; Mature: 24906

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKKNSFNRGKVVEVSSSILSADFANLGKSVEMLTDAGVDYIHVDVMDGNFVPNITIGP
CCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCCCCCCHHH
VVVSAIKKYTTIPFDVHLMINSPGNYIEAFVDAGADMITIHAESDIHLDRIIQKIKSYKK
HHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
SAGLSLVPTSHYNILEYIIFELDLVLIMTVNPGFGGQQFITSQLDKISCVRNLIEKYSLK
HCCCEEECCCCHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TKIAVDGGVNIKNAKSVIEAGADILVVGSAIFNANNMLDYVQQLKSSF
EEEEECCCCCCHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTKKNSFNRGKVVEVSSSILSADFANLGKSVEMLTDAGVDYIHVDVMDGNFVPNITIGP
CCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCCCCCCHHH
VVVSAIKKYTTIPFDVHLMINSPGNYIEAFVDAGADMITIHAESDIHLDRIIQKIKSYKK
HHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
SAGLSLVPTSHYNILEYIIFELDLVLIMTVNPGFGGQQFITSQLDKISCVRNLIEKYSLK
HCCCEEECCCCHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TKIAVDGGVNIKNAKSVIEAGADILVVGSAIFNANNMLDYVQQLKSSF
EEEEECCCCCCHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]