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The map label for this gene is ycfH [H]

Identifier: 88658121

GI number: 88658121

Start: 808223

End: 809005

Strand: Reverse

Name: ycfH [H]

Synonym: ECH_0793

Alternate gene names: 88658121

Gene position: 809005-808223 (Counterclockwise)

Preceding gene: 88658156

Following gene: 88658602

Centisome position: 68.78

GC content: 32.44

Gene sequence:

>783_bases
ATGATTGTAGATTCACATTGCCATTTAAATTATTTTGATCCAAGTGAAATAAAAGATGTAGTTTTGCGTGCAGAGGAGAA
TAATGTAAAATTAATGCAAACTGTATGTACTACTATAGCTGAATTTTCTGATTTAGTAAAAGTTGCAGAAAGTTATAAGC
AAGTTTACCTTTCAGTAGGTGTGCATCCTACTAATAGTGCAAATGGGGAGTCTGTTTCAGTAGATGAGTTAGTAGATTTA
GCTCAACATAGTAAAGTTATTGGATTAGGTGAAACTGGTTTAGATTTTTATAAATGTAGTCAAGTAGGGGAGCAAGAGAA
GAATTTTTTATCTCATATTAATGCATCTAGGGAAACAGGATTGCCTGTTATAATTCACTCAAGAAATGCGGACAAAAGAA
TGATGGAAATTTTGGAATCAGAAATGAAAGAAAGTCCATTTTTAGGACTTATGCATTGTTTTGCATCTTCAAGGGAATTA
GCAATCAAAGCGATAGAATTAGGGTTATATATATCTTTTTCGGGAATAGTGACTTTTAAAAGTGCAAAAGTTGTTCAGGA
AGTAGCAGGGTTTATACCTAAAGATCGTGTGTTAGTGGAAACGGATTCTCCATTCTTATCTCCTGAACCTTATCGTGGGC
AAAGGAATGAGCCAGCTAAGACGAAGTTTGTTGTAGAATATTTAGCTAACTTATGGAATGAAAGCCTTGAGGAAGTTAGT
AATTTAACTACAAAGAATTTTTTTAAACTGTTTAAAAAATGTTCTGAACATTTTCATTTATAA

Upstream 100 bases:

>100_bases
AGTTTTGATGTATTTATAGTTGAATTTGTGTTAATGACCACAGGCATGTTTGTTAGATTGTTTTTAATTTTAGTAAAAAA
AATATGATTAGTGTAAGTAT

Downstream 100 bases:

>100_bases
TATATTATTCTATATATTCAAATAGTATGAACTGTTGTTAATAGTAACGTTGTTATATAGTGACTTTAGGAAAGCTCAGT
ATTTGTTTAAATGTAGAATA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MIVDSHCHLNYFDPSEIKDVVLRAEENNVKLMQTVCTTIAEFSDLVKVAESYKQVYLSVGVHPTNSANGESVSVDELVDL
AQHSKVIGLGETGLDFYKCSQVGEQEKNFLSHINASRETGLPVIIHSRNADKRMMEILESEMKESPFLGLMHCFASSREL
AIKAIELGLYISFSGIVTFKSAKVVQEVAGFIPKDRVLVETDSPFLSPEPYRGQRNEPAKTKFVVEYLANLWNESLEEVS
NLTTKNFFKLFKKCSEHFHL

Sequences:

>Translated_260_residues
MIVDSHCHLNYFDPSEIKDVVLRAEENNVKLMQTVCTTIAEFSDLVKVAESYKQVYLSVGVHPTNSANGESVSVDELVDL
AQHSKVIGLGETGLDFYKCSQVGEQEKNFLSHINASRETGLPVIIHSRNADKRMMEILESEMKESPFLGLMHCFASSREL
AIKAIELGLYISFSGIVTFKSAKVVQEVAGFIPKDRVLVETDSPFLSPEPYRGQRNEPAKTKFVVEYLANLWNESLEEVS
NLTTKNFFKLFKKCSEHFHL
>Mature_260_residues
MIVDSHCHLNYFDPSEIKDVVLRAEENNVKLMQTVCTTIAEFSDLVKVAESYKQVYLSVGVHPTNSANGESVSVDELVDL
AQHSKVIGLGETGLDFYKCSQVGEQEKNFLSHINASRETGLPVIIHSRNADKRMMEILESEMKESPFLGLMHCFASSREL
AIKAIELGLYISFSGIVTFKSAKVVQEVAGFIPKDRVLVETDSPFLSPEPYRGQRNEPAKTKFVVEYLANLWNESLEEVS
NLTTKNFFKLFKKCSEHFHL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=30.8550185873606, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI14042943, Length=268, Percent_Identity=26.865671641791, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=30.5882352941176, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI225903439, Length=239, Percent_Identity=27.1966527196653, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=27.8260869565217, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI225903424, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=41.1764705882353, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI48994985, Length=240, Percent_Identity=29.5833333333333, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=27.9527559055118, Blast_Score=114, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=267, Percent_Identity=25.8426966292135, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=27.5471698113208, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17543026, Length=297, Percent_Identity=26.5993265993266, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=176, Percent_Identity=27.8409090909091, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648690, Length=267, Percent_Identity=26.5917602996255, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI221330018, Length=270, Percent_Identity=26.2962962962963, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24586117, Length=270, Percent_Identity=26.2962962962963, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29286; Mature: 29286

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDSHCHLNYFDPSEIKDVVLRAEENNVKLMQTVCTTIAEFSDLVKVAESYKQVYLSVG
CEECCCCEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VHPTNSANGESVSVDELVDLAQHSKVIGLGETGLDFYKCSQVGEQEKNFLSHINASRETG
CCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCHHHHHHHHCHHHHHHHHHHCCCHHCC
LPVIIHSRNADKRMMEILESEMKESPFLGLMHCFASSRELAIKAIELGLYISFSGIVTFK
CEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHEEEEEEEEEEECCEEEEH
SAKVVQEVAGFIPKDRVLVETDSPFLSPEPYRGQRNEPAKTKFVVEYLANLWNESLEEVS
HHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLTTKNFFKLFKKCSEHFHL
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVDSHCHLNYFDPSEIKDVVLRAEENNVKLMQTVCTTIAEFSDLVKVAESYKQVYLSVG
CEECCCCEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VHPTNSANGESVSVDELVDLAQHSKVIGLGETGLDFYKCSQVGEQEKNFLSHINASRETG
CCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCHHHHHHHHCHHHHHHHHHHCCCHHCC
LPVIIHSRNADKRMMEILESEMKESPFLGLMHCFASSRELAIKAIELGLYISFSGIVTFK
CEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHEEEEEEEEEEECCEEEEH
SAKVVQEVAGFIPKDRVLVETDSPFLSPEPYRGQRNEPAKTKFVVEYLANLWNESLEEVS
HHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLTTKNFFKLFKKCSEHFHL
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]