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The map label for this gene is secB

Identifier: 88658074

GI number: 88658074

Start: 220370

End: 220897

Strand: Direct

Name: secB

Synonym: ECH_0233

Alternate gene names: 88658074

Gene position: 220370-220897 (Clockwise)

Preceding gene: 88657942

Following gene: 88657639

Centisome position: 18.73

GC content: 33.9

Gene sequence:

>528_bases
ATGTCATGTAAATTGAAAGTTAAGGGTCAATATATTAAGGATCTTTCATTTGAAAATCCGAATTCTCCACAAATTTTTTT
GATGATTAGTAAAACCCCACCTGAGATTAATATTTCTATTAATGTTAGTTCTGTAAGTCTTCCAGTAAAAGCACAAGATC
AGAGTAGTGAACAGCCTTCAGATAATAAAGTAGAGCCGTTATATGAAGTTACTCTACAGGTTAATGCAGAAGCTCGAGTT
GGTACTACAGTAGCATTTATTTGCGAAATTAAATATTGTGGTGTATTCTCTATTGAAAGTGATGATGTAAGTATAGAGGA
ATTAAGTCAGCAAGATATAAGAGATGTATTGTTGATTTCTGCTCCAACTATCCTATTCCCATTTGTTAGAGAGTTGATTT
CTAGAGTTACTTCTACAGGGGGATTCCCTCCGTTAATGCTTGATATTGTTGATTTTAGAGCTATGTATGAATCTCAGATG
AAGCAGGGTGTTGGACAGAATGATAATAGTCAGGATCCAGAAAAATAG

Upstream 100 bases:

>100_bases
TTTATTGACAAAAACATATACTGTGTATACTCAATATATTATAGCTTAGTGTACGTTAATCAATAATTAATTACATTATT
TTACTTGGGGGCTTGTTAGT

Downstream 100 bases:

>100_bases
GGTTTTGTTAAGGATAATTTAGTTTGTTAGTTAGGACAGCTTATAGTTTGATTAGTTAAGTTAATACAGGTTTTTGTATT
ATGAAATGTTTAGTGATAAG

Product: preprotein translocase subunit SecB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSCKLKVKGQYIKDLSFENPNSPQIFLMISKTPPEINISINVSSVSLPVKAQDQSSEQPSDNKVEPLYEVTLQVNAEARV
GTTVAFICEIKYCGVFSIESDDVSIEELSQQDIRDVLLISAPTILFPFVRELISRVTSTGGFPPLMLDIVDFRAMYESQM
KQGVGQNDNSQDPEK

Sequences:

>Translated_175_residues
MSCKLKVKGQYIKDLSFENPNSPQIFLMISKTPPEINISINVSSVSLPVKAQDQSSEQPSDNKVEPLYEVTLQVNAEARV
GTTVAFICEIKYCGVFSIESDDVSIEELSQQDIRDVLLISAPTILFPFVRELISRVTSTGGFPPLMLDIVDFRAMYESQM
KQGVGQNDNSQDPEK
>Mature_174_residues
SCKLKVKGQYIKDLSFENPNSPQIFLMISKTPPEINISINVSSVSLPVKAQDQSSEQPSDNKVEPLYEVTLQVNAEARVG
TTVAFICEIKYCGVFSIESDDVSIEELSQQDIRDVLLISAPTILFPFVRELISRVTSTGGFPPLMLDIVDFRAMYESQMK
QGVGQNDNSQDPEK

Specific function: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its r

COG id: COG1952

COG function: function code U; Preprotein translocase subunit SecB

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secB family

Homologues:

Organism=Escherichia coli, GI1790038, Length=163, Percent_Identity=31.2883435582822, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECB_EHRCR (Q2GHM9)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507054.1
- ProteinModelPortal:   Q2GHM9
- SMR:   Q2GHM9
- STRING:   Q2GHM9
- GeneID:   3927887
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0233
- TIGR:   ECH_0233
- eggNOG:   COG1952
- HOGENOM:   HBG294212
- OMA:   GFPPLMI
- PhylomeDB:   Q2GHM9
- ProtClustDB:   PRK05751
- BioCyc:   ECHA205920:ECH_0233-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00821
- InterPro:   IPR003708
- Gene3D:   G3DSA:3.10.420.10
- TIGRFAMs:   TIGR00809

Pfam domain/function: PF02556 SecB; SSF54611 SecB

EC number: NA

Molecular weight: Translated: 19466; Mature: 19335

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCKLKVKGQYIKDLSFENPNSPQIFLMISKTPPEINISINVSSVSLPVKAQDQSSEQPS
CCCEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCCC
DNKVEPLYEVTLQVNAEARVGTTVAFICEIKYCGVFSIESDDVSIEELSQQDIRDVLLIS
CCCCCCEEEEEEEECCCCCCCCEEEEEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHC
APTILFPFVRELISRVTSTGGFPPLMLDIVDFRAMYESQMKQGVGQNDNSQDPEK
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SCKLKVKGQYIKDLSFENPNSPQIFLMISKTPPEINISINVSSVSLPVKAQDQSSEQPS
CCEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCCC
DNKVEPLYEVTLQVNAEARVGTTVAFICEIKYCGVFSIESDDVSIEELSQQDIRDVLLIS
CCCCCCEEEEEEEECCCCCCCCEEEEEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHC
APTILFPFVRELISRVTSTGGFPPLMLDIVDFRAMYESQMKQGVGQNDNSQDPEK
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA