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The map label for this gene is ubiG [H]

Identifier: 88657957

GI number: 88657957

Start: 643013

End: 643738

Strand: Reverse

Name: ubiG [H]

Synonym: ECH_0637

Alternate gene names: 88657957

Gene position: 643738-643013 (Counterclockwise)

Preceding gene: 88658472

Following gene: 88658360

Centisome position: 54.73

GC content: 30.44

Gene sequence:

>726_bases
ATGAGTCAAACGGTTGATCAAAATGAGTTATTAAAGTTTTCAAAAATAGCTGATAAATGGTGGGATGAACATGGCCCATT
AAAAGCCTTGCATGATATACATCCTTTGAGAATGAGATATATTGTTGATTATATAAGTAAGATTATTCCTAAAGCAAATT
TTAAGTCGTTGTCAGTTCTTGATCTTGGATGTGGAGGTGGTTTATTATCAGAATCTATGTCTCGTTTGGGTATGAAAGTT
TTTGGTATAGATGCTAGTGAAGAAAGTATCAATATTGCGAGAGTGCATGCTTCAGAACGTGGTTTATGTAATTTAAAGTA
TTCCTGTATGGATATAGAATCTTTAGTTAATACCGAAGAAAAGTATGATATTATAACTATTATGGAAATAATTGAGCATG
TTGATAATTTACCAGTTTTTGTCAATGCTGTAAGCAATGCATTAAGTGATAATGGGATAATATTCTTATCTACGTTAAAT
AGAACTAAGAAATCTTTTTTGTATGCAATAGTATGTGCTGAATATATTTTAAAATTGGTTCCGCGTAAGACACATCAATG
GGGTAGATTTGTTAAGCCTTCAGAAATCGTAAATTTGTTTTCACTTAATGGTATATGTGTCAAAAACATTATGGGAATGA
ATTTTAATATGATAAGGAGAAGTTGGGTATTATCCGATGATATTTCTGTAAATTATATTTTAGCTGCACAAAAGGTAAGT
AGTTAG

Upstream 100 bases:

>100_bases
TTAATCATGGAGAAGCTCAGTCTATAGTTTATCAGTTCATTACTACAAAATTTTCTGAAGGGAGGCATGTACAAAGAATA
GCAAAAATAGATAATTGTTT

Downstream 100 bases:

>100_bases
GATTATTTTAATTTTACATTTAGTGCGGTATGGCTAGTTAGCCAGCAGATAGGTTTTAATATTATTAGTTTTAATATGAT
AAATTAATAATTAACTATAA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSQTVDQNELLKFSKIADKWWDEHGPLKALHDIHPLRMRYIVDYISKIIPKANFKSLSVLDLGCGGGLLSESMSRLGMKV
FGIDASEESINIARVHASERGLCNLKYSCMDIESLVNTEEKYDIITIMEIIEHVDNLPVFVNAVSNALSDNGIIFLSTLN
RTKKSFLYAIVCAEYILKLVPRKTHQWGRFVKPSEIVNLFSLNGICVKNIMGMNFNMIRRSWVLSDDISVNYILAAQKVS
S

Sequences:

>Translated_241_residues
MSQTVDQNELLKFSKIADKWWDEHGPLKALHDIHPLRMRYIVDYISKIIPKANFKSLSVLDLGCGGGLLSESMSRLGMKV
FGIDASEESINIARVHASERGLCNLKYSCMDIESLVNTEEKYDIITIMEIIEHVDNLPVFVNAVSNALSDNGIIFLSTLN
RTKKSFLYAIVCAEYILKLVPRKTHQWGRFVKPSEIVNLFSLNGICVKNIMGMNFNMIRRSWVLSDDISVNYILAAQKVS
S
>Mature_240_residues
SQTVDQNELLKFSKIADKWWDEHGPLKALHDIHPLRMRYIVDYISKIIPKANFKSLSVLDLGCGGGLLSESMSRLGMKVF
GIDASEESINIARVHASERGLCNLKYSCMDIESLVNTEEKYDIITIMEIIEHVDNLPVFVNAVSNALSDNGIIFLSTLNR
TKKSFLYAIVCAEYILKLVPRKTHQWGRFVKPSEIVNLFSLNGICVKNIMGMNFNMIRRSWVLSDDISVNYILAAQKVSS

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=242, Percent_Identity=35.9504132231405, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1788564, Length=238, Percent_Identity=37.8151260504202, Blast_Score=180, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI115533050, Length=243, Percent_Identity=31.6872427983539, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=284, Percent_Identity=29.2253521126761, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=29.9180327868852, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585589, Length=227, Percent_Identity=30.8370044052863, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 27262; Mature: 27131

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTVDQNELLKFSKIADKWWDEHGPLKALHDIHPLRMRYIVDYISKIIPKANFKSLSVL
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEE
DLGCGGGLLSESMSRLGMKVFGIDASEESINIARVHASERGLCNLKYSCMDIESLVNTEE
EECCCCHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCEEEEEHHCCHHHHHCCCH
KYDIITIMEIIEHVDNLPVFVNAVSNALSDNGIIFLSTLNRTKKSFLYAIVCAEYILKLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHC
PRKTHQWGRFVKPSEIVNLFSLNGICVKNIMGMNFNMIRRSWVLSDDISVNYILAAQKVS
CCCCHHHCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHEECCCCCEEEEEEECCCC
S
C
>Mature Secondary Structure 
SQTVDQNELLKFSKIADKWWDEHGPLKALHDIHPLRMRYIVDYISKIIPKANFKSLSVL
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEE
DLGCGGGLLSESMSRLGMKVFGIDASEESINIARVHASERGLCNLKYSCMDIESLVNTEE
EECCCCHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCEEEEEHHCCHHHHHCCCH
KYDIITIMEIIEHVDNLPVFVNAVSNALSDNGIIFLSTLNRTKKSFLYAIVCAEYILKLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHC
PRKTHQWGRFVKPSEIVNLFSLNGICVKNIMGMNFNMIRRSWVLSDDISVNYILAAQKVS
CCCCHHHCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHEECCCCCEEEEEEECCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA