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The map label for this gene is dapD [H]

Identifier: 88657848

GI number: 88657848

Start: 51551

End: 52390

Strand: Direct

Name: dapD [H]

Synonym: ECH_0058

Alternate gene names: 88657848

Gene position: 51551-52390 (Clockwise)

Preceding gene: 88658248

Following gene: 88658476

Centisome position: 4.38

GC content: 35.48

Gene sequence:

>840_bases
ATGGAAAACTTTTGTAATTTTAAAGACGCTATTGAAGATGCGTGGAATAATTTAGCTAATCTTTCTAGTAATACTTCAAT
TAAAAAAGTTGTTGATGATGTTATGGATCTTTTAGATCAGGGTAAGATCCGCATATGTGAGAAAGTAGGAGATCAATGGG
TAGTTAATGAATGGGCGAAAAAAGCTATATTACTGTGTTTCCGTGTGTATGACATGAATCTTGCAGAAATTAGCAGTGCA
GACTCAATGCTTGGTAACTTATGTTGGTTTGATAAAGTGCAATTGAAATTTGGTAGATGGAGTGCTGATGATTTTAGAGC
AGCAAAAGTTAGAGCTGTACCTGGGTCAATGGTTCGTAAGTCTGCTTATATTGCTCCTAATGTAGTATTGATGCCTAGTT
TTGTAAATGTAGGTGCATATGTAGGTGAAGGTACTATGATTGATACTTGGGCATCTGTCGGAAGTTGTGCTCAAATTGGT
AAGCATTGTCATATTTCTGGTGGTGCAGGGATAGGAGGTGTGTTAGAACCATTAAGTTCTAGACCTGTTGTCATAGAAGA
TAATTGTTTTATTGGTGCTCGTAGTGAAATTGTTGAAGGTGTAGTAGTAGGTGAAGGTTCAGTAATTGCTATGGGTGTTT
ATATTGGGGCTTCTACTAGAATTGTTGATAGAGCATCTGGTGAAATATCTTACGGAAAAATTCCTCCATATTCTGTAGTA
GTGCCTGGTTCTTATGGTAGTGGTGATTTATCATTATATTGTGCTGTGATTGTCAAAAAAGTTGATGATAAAACTAGAAG
TAAAGTATCTATTAATGAACTTTTAAGAGATGATTCTTAA

Upstream 100 bases:

>100_bases
TAACTGGGGCTATTATGGTATAGGTTGTAATGGAATAAAATACTTGTATTTTATTGTCCGTTTTGTTAGCATGAAATTTT
ATGAAAAACTAGTTGTAAAT

Downstream 100 bases:

>100_bases
TACATAACTATAAATCTATATATCATTAGTTTAGAATATAAAAAACAAATGTACTTTATAGGTGAAGTAAGCGTTTTAGC
TAAGTTGTATCGTATATTTT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MENFCNFKDAIEDAWNNLANLSSNTSIKKVVDDVMDLLDQGKIRICEKVGDQWVVNEWAKKAILLCFRVYDMNLAEISSA
DSMLGNLCWFDKVQLKFGRWSADDFRAAKVRAVPGSMVRKSAYIAPNVVLMPSFVNVGAYVGEGTMIDTWASVGSCAQIG
KHCHISGGAGIGGVLEPLSSRPVVIEDNCFIGARSEIVEGVVVGEGSVIAMGVYIGASTRIVDRASGEISYGKIPPYSVV
VPGSYGSGDLSLYCAVIVKKVDDKTRSKVSINELLRDDS

Sequences:

>Translated_279_residues
MENFCNFKDAIEDAWNNLANLSSNTSIKKVVDDVMDLLDQGKIRICEKVGDQWVVNEWAKKAILLCFRVYDMNLAEISSA
DSMLGNLCWFDKVQLKFGRWSADDFRAAKVRAVPGSMVRKSAYIAPNVVLMPSFVNVGAYVGEGTMIDTWASVGSCAQIG
KHCHISGGAGIGGVLEPLSSRPVVIEDNCFIGARSEIVEGVVVGEGSVIAMGVYIGASTRIVDRASGEISYGKIPPYSVV
VPGSYGSGDLSLYCAVIVKKVDDKTRSKVSINELLRDDS
>Mature_279_residues
MENFCNFKDAIEDAWNNLANLSSNTSIKKVVDDVMDLLDQGKIRICEKVGDQWVVNEWAKKAILLCFRVYDMNLAEISSA
DSMLGNLCWFDKVQLKFGRWSADDFRAAKVRAVPGSMVRKSAYIAPNVVLMPSFVNVGAYVGEGTMIDTWASVGSCAQIG
KHCHISGGAGIGGVLEPLSSRPVVIEDNCFIGARSEIVEGVVVGEGSVIAMGVYIGASTRIVDRASGEISYGKIPPYSVV
VPGSYGSGDLSLYCAVIVKKVDDKTRSKVSINELLRDDS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=276, Percent_Identity=56.8840579710145, Blast_Score=288, Evalue=4e-79,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 30148; Mature: 30148

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFCNFKDAIEDAWNNLANLSSNTSIKKVVDDVMDLLDQGKIRICEKVGDQWVVNEWAK
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHH
KAILLCFRVYDMNLAEISSADSMLGNLCWFDKVQLKFGRWSADDFRAAKVRAVPGSMVRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEECCHHHHHH
SAYIAPNVVLMPSFVNVGAYVGEGTMIDTWASVGSCAQIGKHCHISGGAGIGGVLEPLSS
HHCCCCCEEEECCHHHCCEEECCCCEEEHHHHHHHHHHHCCEEEECCCCCCCHHHHHCCC
RPVVIEDNCFIGARSEIVEGVVVGEGSVIAMGVYIGASTRIVDRASGEISYGKIPPYSVV
CCEEEECCCEECCHHHHHCEEEECCCCEEEEEEEECCCEEEEECCCCCEECCCCCCEEEE
VPGSYGSGDLSLYCAVIVKKVDDKTRSKVSINELLRDDS
ECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MENFCNFKDAIEDAWNNLANLSSNTSIKKVVDDVMDLLDQGKIRICEKVGDQWVVNEWAK
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHH
KAILLCFRVYDMNLAEISSADSMLGNLCWFDKVQLKFGRWSADDFRAAKVRAVPGSMVRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEECCHHHHHH
SAYIAPNVVLMPSFVNVGAYVGEGTMIDTWASVGSCAQIGKHCHISGGAGIGGVLEPLSS
HHCCCCCEEEECCHHHCCEEECCCCEEEHHHHHHHHHHHCCEEEECCCCCCCHHHHHCCC
RPVVIEDNCFIGARSEIVEGVVVGEGSVIAMGVYIGASTRIVDRASGEISYGKIPPYSVV
CCEEEECCCEECCHHHHHCEEEECCCCEEEEEEEECCCEEEEECCCCCEECCCCCCEEEE
VPGSYGSGDLSLYCAVIVKKVDDKTRSKVSINELLRDDS
ECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA