| Definition | Ehrlichia chaffeensis str. Arkansas, complete genome. |
|---|---|
| Accession | NC_007799 |
| Length | 1,176,248 |
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The map label for this gene is gyrB [H]
Identifier: 88657694
GI number: 88657694
Start: 626143
End: 628539
Strand: Reverse
Name: gyrB [H]
Synonym: ECH_0620
Alternate gene names: 88657694
Gene position: 628539-626143 (Counterclockwise)
Preceding gene: 88658538
Following gene: 88658358
Centisome position: 53.44
GC content: 31.91
Gene sequence:
>2397_bases ATGGATGATTATAATGCGAGTTCGATTACTGTCTTAAAAGGACTTGATGCGGTTAGAAAAAGACCAGGCATGTATATTGG TGATACTGATGATGGATCTGGATTACACCACATGGTATATGAGGTTATTGATAATTCTATAGATGAAGCGCTTGCTGGAT TTTGCAATAAAATAGATATTGTAATTCAAAGTGATGGGTCTGTTTCTGTTGTGGATAATGGTAGAGGTATACCTGTAGAT ATGCATGAGGACGAAGGCATGTCAGCTGCTGAAGTAATTATGACACAGCTACATGCTGGTGGTAAATTTGACCACAATAG TTATAAGGTTTCAGGTGGACTTCATGGTGTTGGTATATCAGTTGTGAATGCTCTTTCTAGTTGGTTAGAGTTGACCATAT GGCGTAATGGTAAAGAGTATTTTATGCGTTTTGAAGATGGGATAACTGTGAAATCGTTATCTGTGGTTGGTGAGAATACA ACTAAGAAGGGTACTAAAATTACTTTTTTACCATCTAAGAATATTTTTTCATCTATAAATTTTAGTTATTCAACGTTAGA GAATCGTATTAGAGAGCTGTCCTTCCTTAATTCAAATATTAATATGAACCTAAAGGATTTAAGGGGTGCTCAAATATTAA ATTCATCTTTTGGTTTGAAGGATAATTCTAAAGTTAATGATATAGAGGATAGAGGAACTGCTGCTTTTGTAAAATATCTT GATCGCAATAAAACTGCTGTAACCAAAGTTGTTCATATAGAGGGAATTGTGCTTGAACATGGGATTAGCTTAGAACTCTC AATGCATTGGAATGATTCTTACTATGAGAATATGTTATGCTTTACAAATAATATTAGGCAGAAGGATGGTGGTACTCATC TTGCAGGGTTCAGATCAGCTATGACACGTTGTATTAATAATTATGCAACAAATGAGGGTTTCTTAAAAAAGGCAAAAGTA AATATTTTAGGAGAAGATGTAAGGGAAGGTTTAACTTGTGTATTGGCAATAAAATTGCCTGATCCTAAATTTTCATCTCA GACTAAAGATAAATTGGTAAGTTCTGAAGCAAGGACAGCTGTAGAAAATATAGTGTATGAAAAGCTTACAAATATTTTTG AAACTAATCCTAAGTTGGCTACTAGCATTATAGAAAGAATAATTAGATCTGCTAAAGGGAGAGAAGCTGCTCGTAGAGCA AGAGATTTGATAAAAAGTAAGAACGGTTTTGACTTTACTATTTTACCAGGTAAATTGGCAGACTGTCAGGAAAAGTCTCC AGAGTTATCTGAATTATTTATTGTAGAGGGTAATTCTGCAGGTGGTTCTGCAAAGCAAGGGCGTGATAGACGTTCTCAAG CTGTGTTATCTTTGAAGGGAAAGATATTAAATGTAGAACGTGCAAGTTTAGATCGTATATTATCATCAGCAGAAATAGCA TCATTAATTACTGCAATAGGTAGTAATATTGGAACTGAAAATTTTGATATTGAAAAAGTGCGTTATCATAAAGTTATTAT TATGACAGATGCAGATGTTGATGGGTCACACATTAGAACTTTATTGTTAACATTCTTTTTCCGTTATATGCGTGAAGTGA TAGAAAAAGGGTATTTATATATTGCACAGCCTCCACTTTATAAGGTTACAAAACATAAGAAAGAATTTTATATAAAAAAT GATGATATGTTGCATGATTATATAATTAATAATGCAGTAAAAGATCTCACTCTTAATGCAGGTGAAAGCTATTCAGGAAA TAGTTTATCTAAGGTTTTACATCAATGTATGAATATTAGTAAGATAACAAAATCTTATGATAGGGTAATTCCTCAGCATG TTTTAGAATCATTGATTATTTTCTTTAGAAAGCATAATTTTGATTCTGCTGGTGCAATATCTGATCATTTAAATAAAGTT TTTTGTGAATATGAATGGAGTGTTGAAATACCTAAAGAAGATGAGATAAGTATTTTTAGATTATCTCATGGGCTGGTTGA TAAATATTATATTAATAGCGCAATGATGAATTCAGAAGATATTAAGCATGTTATTGCTATGTGTGATGGAATTGAGGATA TTTTTTATAATATGCCTATTTTATCTACTAAAGACAATAATATAAAAATAAGTTCACCTACTTCTTTAGTAGATAATATT ATTGAATTTGGTAAAAAGGATATGACCTTACAGAGGTTTAAAGGTTTAGGTGAAATGAATGCAGATCAATTGTGGGATAC CACATTAAATCCTGAAACAAGGACACTCCTAAAAATTAAAATAGCTGATTGTGAAGCTGCTGATTCAATATTTTCAGTGC TTATGGGTGATTTTGTAGAACCAAGACGTGACTTTATTAATAATAATGCTTTAAATGTACAAAATATTGATGCGTAA
Upstream 100 bases:
>100_bases ATAATAATGCACTGAACTTATAAATAAAGACTTTTTTTACTTTATCTAAAATTTTCTGCAGATATAATGTCTATTAACTT AATTAACTTATAATGTTGCT
Downstream 100 bases:
>100_bases TAACAAGTAGTAAATATTGTTGAATATGTTTTATTAATAAATTACCTCCATTAAAGATATTTTTGTAAAGATAAAGAATT AAAGTAAAAATAGCAAATCA
Product: DNA gyrase, B subunit
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 798; Mature: 798
Protein sequence:
>798_residues MDDYNASSITVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVIDNSIDEALAGFCNKIDIVIQSDGSVSVVDNGRGIPVD MHEDEGMSAAEVIMTQLHAGGKFDHNSYKVSGGLHGVGISVVNALSSWLELTIWRNGKEYFMRFEDGITVKSLSVVGENT TKKGTKITFLPSKNIFSSINFSYSTLENRIRELSFLNSNINMNLKDLRGAQILNSSFGLKDNSKVNDIEDRGTAAFVKYL DRNKTAVTKVVHIEGIVLEHGISLELSMHWNDSYYENMLCFTNNIRQKDGGTHLAGFRSAMTRCINNYATNEGFLKKAKV NILGEDVREGLTCVLAIKLPDPKFSSQTKDKLVSSEARTAVENIVYEKLTNIFETNPKLATSIIERIIRSAKGREAARRA RDLIKSKNGFDFTILPGKLADCQEKSPELSELFIVEGNSAGGSAKQGRDRRSQAVLSLKGKILNVERASLDRILSSAEIA SLITAIGSNIGTENFDIEKVRYHKVIIMTDADVDGSHIRTLLLTFFFRYMREVIEKGYLYIAQPPLYKVTKHKKEFYIKN DDMLHDYIINNAVKDLTLNAGESYSGNSLSKVLHQCMNISKITKSYDRVIPQHVLESLIIFFRKHNFDSAGAISDHLNKV FCEYEWSVEIPKEDEISIFRLSHGLVDKYYINSAMMNSEDIKHVIAMCDGIEDIFYNMPILSTKDNNIKISSPTSLVDNI IEFGKKDMTLQRFKGLGEMNADQLWDTTLNPETRTLLKIKIADCEAADSIFSVLMGDFVEPRRDFINNNALNVQNIDA
Sequences:
>Translated_798_residues MDDYNASSITVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVIDNSIDEALAGFCNKIDIVIQSDGSVSVVDNGRGIPVD MHEDEGMSAAEVIMTQLHAGGKFDHNSYKVSGGLHGVGISVVNALSSWLELTIWRNGKEYFMRFEDGITVKSLSVVGENT TKKGTKITFLPSKNIFSSINFSYSTLENRIRELSFLNSNINMNLKDLRGAQILNSSFGLKDNSKVNDIEDRGTAAFVKYL DRNKTAVTKVVHIEGIVLEHGISLELSMHWNDSYYENMLCFTNNIRQKDGGTHLAGFRSAMTRCINNYATNEGFLKKAKV NILGEDVREGLTCVLAIKLPDPKFSSQTKDKLVSSEARTAVENIVYEKLTNIFETNPKLATSIIERIIRSAKGREAARRA RDLIKSKNGFDFTILPGKLADCQEKSPELSELFIVEGNSAGGSAKQGRDRRSQAVLSLKGKILNVERASLDRILSSAEIA SLITAIGSNIGTENFDIEKVRYHKVIIMTDADVDGSHIRTLLLTFFFRYMREVIEKGYLYIAQPPLYKVTKHKKEFYIKN DDMLHDYIINNAVKDLTLNAGESYSGNSLSKVLHQCMNISKITKSYDRVIPQHVLESLIIFFRKHNFDSAGAISDHLNKV FCEYEWSVEIPKEDEISIFRLSHGLVDKYYINSAMMNSEDIKHVIAMCDGIEDIFYNMPILSTKDNNIKISSPTSLVDNI IEFGKKDMTLQRFKGLGEMNADQLWDTTLNPETRTLLKIKIADCEAADSIFSVLMGDFVEPRRDFINNNALNVQNIDA >Mature_798_residues MDDYNASSITVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVIDNSIDEALAGFCNKIDIVIQSDGSVSVVDNGRGIPVD MHEDEGMSAAEVIMTQLHAGGKFDHNSYKVSGGLHGVGISVVNALSSWLELTIWRNGKEYFMRFEDGITVKSLSVVGENT TKKGTKITFLPSKNIFSSINFSYSTLENRIRELSFLNSNINMNLKDLRGAQILNSSFGLKDNSKVNDIEDRGTAAFVKYL DRNKTAVTKVVHIEGIVLEHGISLELSMHWNDSYYENMLCFTNNIRQKDGGTHLAGFRSAMTRCINNYATNEGFLKKAKV NILGEDVREGLTCVLAIKLPDPKFSSQTKDKLVSSEARTAVENIVYEKLTNIFETNPKLATSIIERIIRSAKGREAARRA RDLIKSKNGFDFTILPGKLADCQEKSPELSELFIVEGNSAGGSAKQGRDRRSQAVLSLKGKILNVERASLDRILSSAEIA SLITAIGSNIGTENFDIEKVRYHKVIIMTDADVDGSHIRTLLLTFFFRYMREVIEKGYLYIAQPPLYKVTKHKKEFYIKN DDMLHDYIINNAVKDLTLNAGESYSGNSLSKVLHQCMNISKITKSYDRVIPQHVLESLIIFFRKHNFDSAGAISDHLNKV FCEYEWSVEIPKEDEISIFRLSHGLVDKYYINSAMMNSEDIKHVIAMCDGIEDIFYNMPILSTKDNNIKISSPTSLVDNI IEFGKKDMTLQRFKGLGEMNADQLWDTTLNPETRTLLKIKIADCEAADSIFSVLMGDFVEPRRDFINNNALNVQNIDA
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=576, Percent_Identity=24.4791666666667, Blast_Score=107, Evalue=3e-23, Organism=Homo sapiens, GI19913406, Length=571, Percent_Identity=24.8686514886165, Blast_Score=106, Evalue=1e-22, Organism=Escherichia coli, GI48994957, Length=813, Percent_Identity=48.0934809348093, Blast_Score=755, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=561, Percent_Identity=38.3244206773619, Blast_Score=363, Evalue=1e-101, Organism=Caenorhabditis elegans, GI17535065, Length=552, Percent_Identity=25, Blast_Score=108, Evalue=1e-23, Organism=Caenorhabditis elegans, GI212645845, Length=513, Percent_Identity=23.0019493177388, Blast_Score=100, Evalue=3e-21, Organism=Saccharomyces cerevisiae, GI6324241, Length=582, Percent_Identity=25.4295532646048, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI17136538, Length=638, Percent_Identity=24.7648902821317, Blast_Score=117, Evalue=3e-26,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 89434; Mature: 89434
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDYNASSITVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVIDNSIDEALAGFCNKIDI CCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE VIQSDGSVSVVDNGRGIPVDMHEDEGMSAAEVIMTQLHAGGKFDHNSYKVSGGLHGVGIS EEECCCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHH VVNALSSWLELTIWRNGKEYFMRFEDGITVKSLSVVGENTTKKGTKITFLPSKNIFSSIN HHHHHHHHHEEEEEECCHHHEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCHHHHHCC FSYSTLENRIRELSFLNSNINMNLKDLRGAQILNSSFGLKDNSKVNDIEDRGTAAFVKYL CHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHH DRNKTAVTKVVHIEGIVLEHGISLELSMHWNDSYYENMLCFTNNIRQKDGGTHLAGFRSA HCCCHHHEEEEEEEEEEEECCCEEEEEEECCCHHHHCCHHHHCCCCCCCCCCHHHHHHHH MTRCINNYATNEGFLKKAKVNILGEDVREGLTCVLAIKLPDPKFSSQTKDKLVSSEARTA HHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH VENIVYEKLTNIFETNPKLATSIIERIIRSAKGREAARRARDLIKSKNGFDFTILPGKLA HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCC DCQEKSPELSELFIVEGNSAGGSAKQGRDRRSQAVLSLKGKILNVERASLDRILSSAEIA CHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHH SLITAIGSNIGTENFDIEKVRYHKVIIMTDADVDGSHIRTLLLTFFFRYMREVIEKGYLY HHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEE IAQPPLYKVTKHKKEFYIKNDDMLHDYIINNAVKDLTLNAGESYSGNSLSKVLHQCMNIS EECCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHCEECCCCCCCCCHHHHHHHHHHHHH KITKSYDRVIPQHVLESLIIFFRKHNFDSAGAISDHLNKVFCEYEWSVEIPKEDEISIFR HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEEECCCCCCEEEEE LSHGLVDKYYINSAMMNSEDIKHVIAMCDGIEDIFYNMPILSTKDNNIKISSPTSLVDNI ECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHCCCEEECCCCCEEECCCHHHHHHH IEFGKKDMTLQRFKGLGEMNADQLWDTTLNPETRTLLKIKIADCEAADSIFSVLMGDFVE HHHCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH PRRDFINNNALNVQNIDA HHHHHHCCCCCCEECCCC >Mature Secondary Structure MDDYNASSITVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVIDNSIDEALAGFCNKIDI CCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE VIQSDGSVSVVDNGRGIPVDMHEDEGMSAAEVIMTQLHAGGKFDHNSYKVSGGLHGVGIS EEECCCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHH VVNALSSWLELTIWRNGKEYFMRFEDGITVKSLSVVGENTTKKGTKITFLPSKNIFSSIN HHHHHHHHHEEEEEECCHHHEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCHHHHHCC FSYSTLENRIRELSFLNSNINMNLKDLRGAQILNSSFGLKDNSKVNDIEDRGTAAFVKYL CHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHH DRNKTAVTKVVHIEGIVLEHGISLELSMHWNDSYYENMLCFTNNIRQKDGGTHLAGFRSA HCCCHHHEEEEEEEEEEEECCCEEEEEEECCCHHHHCCHHHHCCCCCCCCCCHHHHHHHH MTRCINNYATNEGFLKKAKVNILGEDVREGLTCVLAIKLPDPKFSSQTKDKLVSSEARTA HHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH VENIVYEKLTNIFETNPKLATSIIERIIRSAKGREAARRARDLIKSKNGFDFTILPGKLA HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCC DCQEKSPELSELFIVEGNSAGGSAKQGRDRRSQAVLSLKGKILNVERASLDRILSSAEIA CHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHH SLITAIGSNIGTENFDIEKVRYHKVIIMTDADVDGSHIRTLLLTFFFRYMREVIEKGYLY HHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEE IAQPPLYKVTKHKKEFYIKNDDMLHDYIINNAVKDLTLNAGESYSGNSLSKVLHQCMNIS EECCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHCEECCCCCCCCCHHHHHHHHHHHHH KITKSYDRVIPQHVLESLIIFFRKHNFDSAGAISDHLNKVFCEYEWSVEIPKEDEISIFR HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEEECCCCCCEEEEE LSHGLVDKYYINSAMMNSEDIKHVIAMCDGIEDIFYNMPILSTKDNNIKISSPTSLVDNI ECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHCCCEEECCCCCEEECCCHHHHHHH IEFGKKDMTLQRFKGLGEMNADQLWDTTLNPETRTLLKIKIADCEAADSIFSVLMGDFVE HHHCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH PRRDFINNNALNVQNIDA HHHHHHCCCCCCEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA