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The map label for this gene is asd [H]

Identifier: 88657690

GI number: 88657690

Start: 13757

End: 14767

Strand: Direct

Name: asd [H]

Synonym: ECH_0016

Alternate gene names: 88657690

Gene position: 13757-14767 (Clockwise)

Preceding gene: 88658046

Following gene: 88657937

Centisome position: 1.17

GC content: 33.33

Gene sequence:

>1011_bases
ATGAGTTATAAAATAGCAGTAGTAGGTGCCACAGGAAATGTAGGTAGGGTTATTCTGAACATTCTGGCAAGCAGGTCATT
TCCAGCAAAAGAGGTTGTAGCGCTAGCATCAAAAAAGTCTATAGGTAAAAAATTAAGTTATGGAGATGAAGTATTAGAAT
CCCAAGACTTAGACAGTTACAACTTTACTAATACAGACATAGCAATTTTTTCAGCTGGATCTTCAATATCACAACAGTAC
GCACGAACAGCAGCAAATAAAGGATGTATAATTATCGACAATACTTCCTTATTTCGTATGGAAGATGAAATACCATTAGT
AGTTCCAGAAATCAATCCAGAAGACATAGCTCAATATTATAAACATAACATTATTGCCAATCCAAATTGCTCTACTATAC
AAATGCTTTTAGCTTTAAATCCATTACATAAAATATCGAAAATAAAGAGAGTTGTAGTATCAACGTATCAATCAGTTTCT
GGTGCAGGAAAATCTGCAATGGATGAACTCTATTCACAAACCAAGGGCACGTTTATGAACCAAAACATTGCCCCTAAACA
ATTTACAAAAAGAATTGCTTTTAACTGCATTCCACACATAGATGTTTTTATGGAAGATGGTTCAACAAAAGAAGAATGGA
AAATGGCCGTAGAAACAAAGAAAATATTAGATAATAATATAGAAGTAAGTGCAACATGTGTTAGGGTTCCAGTATTTGTA
TCACATTCTGAATCATTAAACGTTGAATTCTTATCTGAGATTTCAGAAGAAGAAGCTTATGAAGCATTAGAAAATGCTCC
AGGAGTTATAATCCTTGATAGGAGAGAAGATGGTGGATACGCAACACCATTAGACAGTGTACATGAAGACGAAGTTTATG
TATCAAGATTAAGAAAAGACAACACAGTAAAACATGGTCTTAATATGTGGTTAGTAAGTGACAATTTAAGAAAAGGTGCA
GCATTAAATGCAGTACAAATAGCAGAAATACTTGTTAATGATTACCTTTAA

Upstream 100 bases:

>100_bases
TTAATTAAAGCAGCACTGAACGATGCTTTAAAAAAGTCATCCGATTACAATAAAAATCTTGTAGGTTCTTTATTATCATT
TGGCATATAATAGAAAAGAC

Downstream 100 bases:

>100_bases
AAAGATATTTTTAAAATAGCAAATATTGTAACACTATATGAATTACCAGATTTATTTCAGCACCGCTTATTTTTATAATG
CACACGAGTAATTCCTTTCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSYKIAVVGATGNVGRVILNILASRSFPAKEVVALASKKSIGKKLSYGDEVLESQDLDSYNFTNTDIAIFSAGSSISQQY
ARTAANKGCIIIDNTSLFRMEDEIPLVVPEINPEDIAQYYKHNIIANPNCSTIQMLLALNPLHKISKIKRVVVSTYQSVS
GAGKSAMDELYSQTKGTFMNQNIAPKQFTKRIAFNCIPHIDVFMEDGSTKEEWKMAVETKKILDNNIEVSATCVRVPVFV
SHSESLNVEFLSEISEEEAYEALENAPGVIILDRREDGGYATPLDSVHEDEVYVSRLRKDNTVKHGLNMWLVSDNLRKGA
ALNAVQIAEILVNDYL

Sequences:

>Translated_336_residues
MSYKIAVVGATGNVGRVILNILASRSFPAKEVVALASKKSIGKKLSYGDEVLESQDLDSYNFTNTDIAIFSAGSSISQQY
ARTAANKGCIIIDNTSLFRMEDEIPLVVPEINPEDIAQYYKHNIIANPNCSTIQMLLALNPLHKISKIKRVVVSTYQSVS
GAGKSAMDELYSQTKGTFMNQNIAPKQFTKRIAFNCIPHIDVFMEDGSTKEEWKMAVETKKILDNNIEVSATCVRVPVFV
SHSESLNVEFLSEISEEEAYEALENAPGVIILDRREDGGYATPLDSVHEDEVYVSRLRKDNTVKHGLNMWLVSDNLRKGA
ALNAVQIAEILVNDYL
>Mature_335_residues
SYKIAVVGATGNVGRVILNILASRSFPAKEVVALASKKSIGKKLSYGDEVLESQDLDSYNFTNTDIAIFSAGSSISQQYA
RTAANKGCIIIDNTSLFRMEDEIPLVVPEINPEDIAQYYKHNIIANPNCSTIQMLLALNPLHKISKIKRVVVSTYQSVSG
AGKSAMDELYSQTKGTFMNQNIAPKQFTKRIAFNCIPHIDVFMEDGSTKEEWKMAVETKKILDNNIEVSATCVRVPVFVS
HSESLNVEFLSEISEEEAYEALENAPGVIILDRREDGGYATPLDSVHEDEVYVSRLRKDNTVKHGLNMWLVSDNLRKGAA
LNAVQIAEILVNDYL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=36.094674556213, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1789841, Length=354, Percent_Identity=26.5536723163842, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=399, Percent_Identity=28.3208020050125, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37204; Mature: 37073

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKIAVVGATGNVGRVILNILASRSFPAKEVVALASKKSIGKKLSYGDEVLESQDLDSY
CCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
NFTNTDIAIFSAGSSISQQYARTAANKGCIIIDNTSLFRMEDEIPLVVPEINPEDIAQYY
CCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCEEEECCCCCEEECCCCHHHHHHHH
KHNIIANPNCSTIQMLLALNPLHKISKIKRVVVSTYQSVSGAGKSAMDELYSQTKGTFMN
HHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
QNIAPKQFTKRIAFNCIPHIDVFMEDGSTKEEWKMAVETKKILDNNIEVSATCVRVPVFV
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEE
SHSESLNVEFLSEISEEEAYEALENAPGVIILDRREDGGYATPLDSVHEDEVYVSRLRKD
ECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
NTVKHGLNMWLVSDNLRKGAALNAVQIAEILVNDYL
CHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYKIAVVGATGNVGRVILNILASRSFPAKEVVALASKKSIGKKLSYGDEVLESQDLDSY
CEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
NFTNTDIAIFSAGSSISQQYARTAANKGCIIIDNTSLFRMEDEIPLVVPEINPEDIAQYY
CCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCEEEECCCCCEEECCCCHHHHHHHH
KHNIIANPNCSTIQMLLALNPLHKISKIKRVVVSTYQSVSGAGKSAMDELYSQTKGTFMN
HHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
QNIAPKQFTKRIAFNCIPHIDVFMEDGSTKEEWKMAVETKKILDNNIEVSATCVRVPVFV
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEE
SHSESLNVEFLSEISEEEAYEALENAPGVIILDRREDGGYATPLDSVHEDEVYVSRLRKD
ECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
NTVKHGLNMWLVSDNLRKGAALNAVQIAEILVNDYL
CHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]