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The map label for this gene is htpG [H]

Identifier: 88657577

GI number: 88657577

Start: 874547

End: 876460

Strand: Reverse

Name: htpG [H]

Synonym: ECH_0853

Alternate gene names: 88657577

Gene position: 876460-874547 (Counterclockwise)

Preceding gene: 88658346

Following gene: 88658482

Centisome position: 74.51

GC content: 31.09

Gene sequence:

>1914_bases
ATGCAAGATGTTATAAATTCTGAGAAATTGAAGTTTGATGCCGAAGTAGGTAAGGTGTTAAAGCTTGTTATACACTCTCT
TTATACAAATAAGGATATTTTTTTAAGAGAATTAGTTTCTAATGCTTCAGATGCATGTGATAAGTTACGTTATGAATCTC
TATCTAATCAAGATTTAATAGACCAAGATTCTGATTTTAAAATAGTTATCAGTGTAGACCAAGATAAAAATAGATTATAT
ATATCTGATAATGGTATTGGAATGAATAGGCAAGACCTAATAGATAATTTAGGTACCATAGCGCATTCTGGTACACAAAG
GTTTTTGGATGAAATTAATAATGGAACTTCTTCTCAAGGTGTTGTTGAACTAATAGGTAAATTTGGTGTAGGTTTTTATT
CTGCATTTATGGTGGCAAGTGAGGTTATAGTTGAGTCTCGTAAAGCTGGAGAATCTATAGGGTATCAGTGGAAATCTCAT
GGAGATGGAGAATTTACTATTTCTCAACTGGAGGATAATCAAATTTCCCGTGGAACTAAGATTACTTTAATATTAAAGCC
TGAAGAATCTGAATTTACTGATAGGTTTCGTATAGAACATATTATTACTACATATTCTTACCATATTAATTATCCAGTTT
ATTTCTTAAATGATAAGGGAGAAGAAGAGAAGTTAAATAGTGATGCTGCTATTTGGACAAAATCTAAAGGTGAAATATCT
GCAGAAGAACATCAAAATTTTTTCCGTACAGTAGCTCATGTTGGTGGTGAACCTTGGATGATATTACATAATAAAAATGA
AGGGGTAGTAGAGTACACTAATTTATTGTATATACCATCTATTAAACCATTTGATTTATTTCATCCTGATAGGAAATGTT
CAGTAAAATTATATGTGAATAAAGTATTCATTACTGAAGATAATGTACAAATTATACCTCAGTATTTGAGATTTTTAAAA
GGTATAATAGATTCTTCAGACCTACCTTTAAATATCAGCCGTGAAACTTTACAAAATAACAAAATTATTGAGAAGATAAA
ACAATCTATAGTTAATAGAGTACTATCTGAACTTAAGAAAAAAGCTGAGAGTGATATTAAAGATTATAAAAAATTTTGGG
AAAATTTTGGCTCAGTATTGAAGGAAGGATTGTGTGAATCGATGAACACAGAGTTTCGTGAAGAGTTAATGTCAGCATGT
CGTTTTTATAGTACATACAGTGATGATTCGTTAATTAGCTTGGAAGATTATATTGAAAGAATGAAAGCAGGGCAGGATAA
TATTTATTATTTAACTGGTAATGATTTAGATTCTGTGAAAAAGAGTCCTCAACTGGAAGGGTTTATAAGTCGCGGGATAG
AAGTTATACTGTTAGTTGATCCTGTAGATGATTTTTGGACGAATGTGGTAACTGATTATCAAAAGGTGCCTTTAAAATCA
GTTATACGAGCGGATGAAGATTTAGAAAAACTTGCTCATCTTGATAAGAGTGAAGAAATTAAGGAAAATGAAGATGAGAG
CGTTGATTCTAAAGAAAAAGTAGACACATTTGTTAAGTATGCAGCTCAAGTACTTGATAAATTAGTCAGTAGCGTTAGGG
TATCGAAAAAATTAACAAATAGCCCAGTATGTTTAGCTGTAGCGGATGGTTCCATGGATATTAGAATGGAAAGATTTTTA
AGGGAACAGAAGCAATTGAATTATAAGAGCACAAAGATTTTGGAGATCAATCCTAAACATCCTATTGTTACTAAAATGAT
AGATGAACATGCTAATGCTGGGGAAAGTGTTACATTAGAAAACATGTTGCATTTATTATTGAATCAAGCATGTATTCTTG
AAGGAGAAGAGCTACAGGATGTTAGTGATTTTGCTGAAAGAATGAATAATATATTGGCTAAGGTTTATCAATAG

Upstream 100 bases:

>100_bases
TGGATTTACTACAAATTTATGAGAATTAGTAATTTAATAACTTGAAAATTGTTGCTGTAGTTATTACTTATTTATTTAAT
ACTAGTTTAAGAGGGTTAAT

Downstream 100 bases:

>100_bases
CTCTTAGATATGGCTTAATCTGACTATAGTATTATATACATGACTATTTGTAGGTAACTAGATATGTGTTTTTGAAGAGG
TATGTCAGAGATGGGTTTAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MQDVINSEKLKFDAEVGKVLKLVIHSLYTNKDIFLRELVSNASDACDKLRYESLSNQDLIDQDSDFKIVISVDQDKNRLY
ISDNGIGMNRQDLIDNLGTIAHSGTQRFLDEINNGTSSQGVVELIGKFGVGFYSAFMVASEVIVESRKAGESIGYQWKSH
GDGEFTISQLEDNQISRGTKITLILKPEESEFTDRFRIEHIITTYSYHINYPVYFLNDKGEEEKLNSDAAIWTKSKGEIS
AEEHQNFFRTVAHVGGEPWMILHNKNEGVVEYTNLLYIPSIKPFDLFHPDRKCSVKLYVNKVFITEDNVQIIPQYLRFLK
GIIDSSDLPLNISRETLQNNKIIEKIKQSIVNRVLSELKKKAESDIKDYKKFWENFGSVLKEGLCESMNTEFREELMSAC
RFYSTYSDDSLISLEDYIERMKAGQDNIYYLTGNDLDSVKKSPQLEGFISRGIEVILLVDPVDDFWTNVVTDYQKVPLKS
VIRADEDLEKLAHLDKSEEIKENEDESVDSKEKVDTFVKYAAQVLDKLVSSVRVSKKLTNSPVCLAVADGSMDIRMERFL
REQKQLNYKSTKILEINPKHPIVTKMIDEHANAGESVTLENMLHLLLNQACILEGEELQDVSDFAERMNNILAKVYQ

Sequences:

>Translated_637_residues
MQDVINSEKLKFDAEVGKVLKLVIHSLYTNKDIFLRELVSNASDACDKLRYESLSNQDLIDQDSDFKIVISVDQDKNRLY
ISDNGIGMNRQDLIDNLGTIAHSGTQRFLDEINNGTSSQGVVELIGKFGVGFYSAFMVASEVIVESRKAGESIGYQWKSH
GDGEFTISQLEDNQISRGTKITLILKPEESEFTDRFRIEHIITTYSYHINYPVYFLNDKGEEEKLNSDAAIWTKSKGEIS
AEEHQNFFRTVAHVGGEPWMILHNKNEGVVEYTNLLYIPSIKPFDLFHPDRKCSVKLYVNKVFITEDNVQIIPQYLRFLK
GIIDSSDLPLNISRETLQNNKIIEKIKQSIVNRVLSELKKKAESDIKDYKKFWENFGSVLKEGLCESMNTEFREELMSAC
RFYSTYSDDSLISLEDYIERMKAGQDNIYYLTGNDLDSVKKSPQLEGFISRGIEVILLVDPVDDFWTNVVTDYQKVPLKS
VIRADEDLEKLAHLDKSEEIKENEDESVDSKEKVDTFVKYAAQVLDKLVSSVRVSKKLTNSPVCLAVADGSMDIRMERFL
REQKQLNYKSTKILEINPKHPIVTKMIDEHANAGESVTLENMLHLLLNQACILEGEELQDVSDFAERMNNILAKVYQ
>Mature_637_residues
MQDVINSEKLKFDAEVGKVLKLVIHSLYTNKDIFLRELVSNASDACDKLRYESLSNQDLIDQDSDFKIVISVDQDKNRLY
ISDNGIGMNRQDLIDNLGTIAHSGTQRFLDEINNGTSSQGVVELIGKFGVGFYSAFMVASEVIVESRKAGESIGYQWKSH
GDGEFTISQLEDNQISRGTKITLILKPEESEFTDRFRIEHIITTYSYHINYPVYFLNDKGEEEKLNSDAAIWTKSKGEIS
AEEHQNFFRTVAHVGGEPWMILHNKNEGVVEYTNLLYIPSIKPFDLFHPDRKCSVKLYVNKVFITEDNVQIIPQYLRFLK
GIIDSSDLPLNISRETLQNNKIIEKIKQSIVNRVLSELKKKAESDIKDYKKFWENFGSVLKEGLCESMNTEFREELMSAC
RFYSTYSDDSLISLEDYIERMKAGQDNIYYLTGNDLDSVKKSPQLEGFISRGIEVILLVDPVDDFWTNVVTDYQKVPLKS
VIRADEDLEKLAHLDKSEEIKENEDESVDSKEKVDTFVKYAAQVLDKLVSSVRVSKKLTNSPVCLAVADGSMDIRMERFL
REQKQLNYKSTKILEINPKHPIVTKMIDEHANAGESVTLENMLHLLLNQACILEGEELQDVSDFAERMNNILAKVYQ

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=33.0409356725146, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI155722983, Length=639, Percent_Identity=32.0813771517997, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI154146191, Length=419, Percent_Identity=32.2195704057279, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI153792590, Length=419, Percent_Identity=32.2195704057279, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI20149594, Length=419, Percent_Identity=32.4582338902148, Blast_Score=211, Evalue=2e-54,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=43.4645669291339, Blast_Score=499, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17559162, Length=682, Percent_Identity=33.8709677419355, Blast_Score=377, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17542208, Length=680, Percent_Identity=34.8529411764706, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI115535205, Length=647, Percent_Identity=31.9938176197836, Blast_Score=307, Evalue=9e-84,
Organism=Caenorhabditis elegans, GI115535167, Length=453, Percent_Identity=35.3200883002208, Blast_Score=262, Evalue=5e-70,
Organism=Saccharomyces cerevisiae, GI6323840, Length=689, Percent_Identity=33.6719883889695, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6325016, Length=693, Percent_Identity=33.1890331890332, Blast_Score=372, Evalue=1e-104,
Organism=Drosophila melanogaster, GI21357739, Length=686, Percent_Identity=34.2565597667638, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24586016, Length=597, Percent_Identity=33.500837520938, Blast_Score=322, Evalue=6e-88,
Organism=Drosophila melanogaster, GI17647529, Length=419, Percent_Identity=34.1288782816229, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72882; Mature: 72882

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVINSEKLKFDAEVGKVLKLVIHSLYTNKDIFLRELVSNASDACDKLRYESLSNQDLI
CCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQDSDFKIVISVDQDKNRLYISDNGIGMNRQDLIDNLGTIAHSGTQRFLDEINNGTSSQG
CCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCH
VVELIGKFGVGFYSAFMVASEVIVESRKAGESIGYQWKSHGDGEFTISQLEDNQISRGTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCEEEEECCCCCCCCCCE
ITLILKPEESEFTDRFRIEHIITTYSYHINYPVYFLNDKGEEEKLNSDAAIWTKSKGEIS
EEEEECCCCCCHHHHHHHHHHEEEEEEEECCEEEEECCCCCHHHCCCCCEEEECCCCCCC
AEEHQNFFRTVAHVGGEPWMILHNKNEGVVEYTNLLYIPSIKPFDLFHPDRKCSVKLYVN
HHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEE
KVFITEDNVQIIPQYLRFLKGIIDSSDLPLNISRETLQNNKIIEKIKQSIVNRVLSELKK
EEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
KAESDIKDYKKFWENFGSVLKEGLCESMNTEFREELMSACRFYSTYSDDSLISLEDYIER
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
MKAGQDNIYYLTGNDLDSVKKSPQLEGFISRGIEVILLVDPVDDFWTNVVTDYQKVPLKS
HHCCCCCEEEEECCCHHHHHCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCHHH
VIRADEDLEKLAHLDKSEEIKENEDESVDSKEKVDTFVKYAAQVLDKLVSSVRVSKKLTN
HHCCCHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPVCLAVADGSMDIRMERFLREQKQLNYKSTKILEINPKHPIVTKMIDEHANAGESVTLE
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEHH
NMLHLLLNQACILEGEELQDVSDFAERMNNILAKVYQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDVINSEKLKFDAEVGKVLKLVIHSLYTNKDIFLRELVSNASDACDKLRYESLSNQDLI
CCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQDSDFKIVISVDQDKNRLYISDNGIGMNRQDLIDNLGTIAHSGTQRFLDEINNGTSSQG
CCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCH
VVELIGKFGVGFYSAFMVASEVIVESRKAGESIGYQWKSHGDGEFTISQLEDNQISRGTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCEEEEECCCCCCCCCCE
ITLILKPEESEFTDRFRIEHIITTYSYHINYPVYFLNDKGEEEKLNSDAAIWTKSKGEIS
EEEEECCCCCCHHHHHHHHHHEEEEEEEECCEEEEECCCCCHHHCCCCCEEEECCCCCCC
AEEHQNFFRTVAHVGGEPWMILHNKNEGVVEYTNLLYIPSIKPFDLFHPDRKCSVKLYVN
HHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEE
KVFITEDNVQIIPQYLRFLKGIIDSSDLPLNISRETLQNNKIIEKIKQSIVNRVLSELKK
EEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
KAESDIKDYKKFWENFGSVLKEGLCESMNTEFREELMSACRFYSTYSDDSLISLEDYIER
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
MKAGQDNIYYLTGNDLDSVKKSPQLEGFISRGIEVILLVDPVDDFWTNVVTDYQKVPLKS
HHCCCCCEEEEECCCHHHHHCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCHHH
VIRADEDLEKLAHLDKSEEIKENEDESVDSKEKVDTFVKYAAQVLDKLVSSVRVSKKLTN
HHCCCHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPVCLAVADGSMDIRMERFLREQKQLNYKSTKILEINPKHPIVTKMIDEHANAGESVTLE
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEHH
NMLHLLLNQACILEGEELQDVSDFAERMNNILAKVYQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA