Click here to switch to the map view.

The map label for this gene is nuoN

Identifier: 88608865

GI number: 88608865

Start: 613253

End: 614629

Strand: Direct

Name: nuoN

Synonym: NSE_0692

Alternate gene names: 88608865

Gene position: 613253-614629 (Clockwise)

Preceding gene: 88608616

Following gene: 88608177

Centisome position: 71.39

GC content: 39.0

Gene sequence:

>1377_bases
ATGAATCAATACCTGTTTTTACTACCTGAAATTACACTTTTTACTCTTTCCTGTTTACTGCTTTTCTTAAAGAGCAGGAA
TGAATTTGGACTAATTGCAGTATTGATCGCTTTAGCAGCTACATTTTTCAGTCAAACTTATGCATCAGCCGAAATCTTAA
ACGGGATGCTACTAATTTCCCCTTTCACACAAACTGTCAAACTTGTAATACTCGCTTTTGCATGTATCTTTTTCATACAG
GCCATCGCTGTAAAGCAGTCATATTCAAAAAACTTTTCGGTTTTGGTACTGCTTTCACTCCTTGGAATGCTGCTTTCTGT
TTCGTCCAACACTTTGGCATCCCTATATCTAGCTGTAGAACTTCATAGCATAGGACAATACATACTAGCTTGTATAAAAC
ATAAATCGATTAAGAGTGCAGAGGCTGGTGTGAAGTATACACTTCTGGGAACATTCATGTCAGCAGTAATGATATATGGA
ATATCGTTAATCTTCATGGTCTCCGGTGACCTTTCACTAAAAAGCCTTTTTATAGCGGACAATAAGATCCACTCTATAGG
AGTTCTGCTATTCATTTCAGGACTGATGTTTAAGATTGCTGCTACACCCTTTCATTCGTGGGTAGGTGACATTTACGAGG
GATCTCCTACGGTTTCTACAACATTTTTTGCTGTACTACCGAAGCTTTCACTCATCGTGGTGTTAGTTTCACTTATCTCT
AACTTAGAACCTATTACATACGATGGATCTACTCACCCTACTGAGCTAATAAAGAATTCTCAGTATCTTAGGAACATATT
ATTTATTTCTGGCATTCTATCCATTGCTTTTGGTACTTTTTCTGCATTTGGACAAAAGAATATCAAGAGATTTATAGGAT
TTGCATCTGTCACACACGTGGGTTATATGCTGCTTGGGGTAAGTAGCTCAGCAAGTCTATCGTTTGGAAATCCAGGAGTT
GCATATGCTCTGGTATATTCCTTTACAAACCTTGGCATTCTTTCTGTCGTATTGATGCTAAAAGACAAACATATCACTTC
TCTGAAAAAGCTTAGATGCTCGAATAACTTGGTTGCTCTCGCATTTGTGCTCTTGCTCTTCTCCTCCGCTGGAGTACCAC
CGTTTATAGGGTTCTGGAGCAAGGCATATGTAGTGAAGACTCTCGTTGAAACAGATCATGTTCCCACAGCCCTTTTTTCA
ATGCTTGCTGGCGTGATTTCTGCTTTCTACTACGCAAGAATAGCTAAGGAAACCTACTTTACAAACATAGCAGAAGAGGG
CATCAAAGTAAGCTTGGGACATAATACACTTCTCACGTCGATAGTCGTTTTGTGTGCACTGTTCTCAACATTTGGGTTTG
TACTTCTGATCTGCTAA

Upstream 100 bases:

>100_bases
TTCAAGATATTCACCTACACGAGTCTATACCACTCATTACTTTAATCATCCTAGTGATGTTTCTGGGTCTCCGCCCGAGC
TTTCTTCTTAATTTTTTGAG

Downstream 100 bases:

>100_bases
TCCGTGTCATTATCATTCCTAACATCAGTTTCTTGTACACAGGAGTTGCTACTGCGTCTGTATGGTCGTAGCCAGGATTA
CAATTGTACCGCGTACATAC

Product: NADH dehydrogenase I subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNQYLFLLPEITLFTLSCLLLFLKSRNEFGLIAVLIALAATFFSQTYASAEILNGMLLISPFTQTVKLVILAFACIFFIQ
AIAVKQSYSKNFSVLVLLSLLGMLLSVSSNTLASLYLAVELHSIGQYILACIKHKSIKSAEAGVKYTLLGTFMSAVMIYG
ISLIFMVSGDLSLKSLFIADNKIHSIGVLLFISGLMFKIAATPFHSWVGDIYEGSPTVSTTFFAVLPKLSLIVVLVSLIS
NLEPITYDGSTHPTELIKNSQYLRNILFISGILSIAFGTFSAFGQKNIKRFIGFASVTHVGYMLLGVSSSASLSFGNPGV
AYALVYSFTNLGILSVVLMLKDKHITSLKKLRCSNNLVALAFVLLLFSSAGVPPFIGFWSKAYVVKTLVETDHVPTALFS
MLAGVISAFYYARIAKETYFTNIAEEGIKVSLGHNTLLTSIVVLCALFSTFGFVLLIC

Sequences:

>Translated_458_residues
MNQYLFLLPEITLFTLSCLLLFLKSRNEFGLIAVLIALAATFFSQTYASAEILNGMLLISPFTQTVKLVILAFACIFFIQ
AIAVKQSYSKNFSVLVLLSLLGMLLSVSSNTLASLYLAVELHSIGQYILACIKHKSIKSAEAGVKYTLLGTFMSAVMIYG
ISLIFMVSGDLSLKSLFIADNKIHSIGVLLFISGLMFKIAATPFHSWVGDIYEGSPTVSTTFFAVLPKLSLIVVLVSLIS
NLEPITYDGSTHPTELIKNSQYLRNILFISGILSIAFGTFSAFGQKNIKRFIGFASVTHVGYMLLGVSSSASLSFGNPGV
AYALVYSFTNLGILSVVLMLKDKHITSLKKLRCSNNLVALAFVLLLFSSAGVPPFIGFWSKAYVVKTLVETDHVPTALFS
MLAGVISAFYYARIAKETYFTNIAEEGIKVSLGHNTLLTSIVVLCALFSTFGFVLLIC
>Mature_458_residues
MNQYLFLLPEITLFTLSCLLLFLKSRNEFGLIAVLIALAATFFSQTYASAEILNGMLLISPFTQTVKLVILAFACIFFIQ
AIAVKQSYSKNFSVLVLLSLLGMLLSVSSNTLASLYLAVELHSIGQYILACIKHKSIKSAEAGVKYTLLGTFMSAVMIYG
ISLIFMVSGDLSLKSLFIADNKIHSIGVLLFISGLMFKIAATPFHSWVGDIYEGSPTVSTTFFAVLPKLSLIVVLVSLIS
NLEPITYDGSTHPTELIKNSQYLRNILFISGILSIAFGTFSAFGQKNIKRFIGFASVTHVGYMLLGVSSSASLSFGNPGV
AYALVYSFTNLGILSVVLMLKDKHITSLKKLRCSNNLVALAFVLLLFSSAGVPPFIGFWSKAYVVKTLVETDHVPTALFS
MLAGVISAFYYARIAKETYFTNIAEEGIKVSLGHNTLLTSIVVLCALFSTFGFVLLIC

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=382, Percent_Identity=29.8429319371728, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49818; Mature: 49818

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQYLFLLPEITLFTLSCLLLFLKSRNEFGLIAVLIALAATFFSQTYASAEILNGMLLIS
CCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
PFTQTVKLVILAFACIFFIQAIAVKQSYSKNFSVLVLLSLLGMLLSVSSNTLASLYLAVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LHSIGQYILACIKHKSIKSAEAGVKYTLLGTFMSAVMIYGISLIFMVSGDLSLKSLFIAD
HHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
NKIHSIGVLLFISGLMFKIAATPFHSWVGDIYEGSPTVSTTFFAVLPKLSLIVVLVSLIS
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NLEPITYDGSTHPTELIKNSQYLRNILFISGILSIAFGTFSAFGQKNIKRFIGFASVTHV
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYMLLGVSSSASLSFGNPGVAYALVYSFTNLGILSVVLMLKDKHITSLKKLRCSNNLVAL
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHH
AFVLLLFSSAGVPPFIGFWSKAYVVKTLVETDHVPTALFSMLAGVISAFYYARIAKETYF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TNIAEEGIKVSLGHNTLLTSIVVLCALFSTFGFVLLIC
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQYLFLLPEITLFTLSCLLLFLKSRNEFGLIAVLIALAATFFSQTYASAEILNGMLLIS
CCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
PFTQTVKLVILAFACIFFIQAIAVKQSYSKNFSVLVLLSLLGMLLSVSSNTLASLYLAVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LHSIGQYILACIKHKSIKSAEAGVKYTLLGTFMSAVMIYGISLIFMVSGDLSLKSLFIAD
HHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
NKIHSIGVLLFISGLMFKIAATPFHSWVGDIYEGSPTVSTTFFAVLPKLSLIVVLVSLIS
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NLEPITYDGSTHPTELIKNSQYLRNILFISGILSIAFGTFSAFGQKNIKRFIGFASVTHV
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYMLLGVSSSASLSFGNPGVAYALVYSFTNLGILSVVLMLKDKHITSLKKLRCSNNLVAL
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHH
AFVLLLFSSAGVPPFIGFWSKAYVVKTLVETDHVPTALFSMLAGVISAFYYARIAKETYF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TNIAEEGIKVSLGHNTLLTSIVVLCALFSTFGFVLLIC
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA