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The map label for this gene is atpD

Identifier: 88608676

GI number: 88608676

Start: 679044

End: 680468

Strand: Reverse

Name: atpD

Synonym: NSE_0763

Alternate gene names: 88608676

Gene position: 680468-679044 (Counterclockwise)

Preceding gene: 88608801

Following gene: 88608001

Centisome position: 79.22

GC content: 44.35

Gene sequence:

>1425_bases
ATGCCAGTAAGTATAGGAAAAATAGTTCGAGTCGTTGGTCCGACAGTTGATGTAAAGTTCGAAGACGGCACATTGCCAAA
AATAGAGAATGCTCTTACCTGTGACAATAATGGAAAGATCCTATACTTAGAAGTTGCACAGCAATTGGGAGATGGAATAG
TCCGCGCTGTAGCAATGGATTCGACGGATGGTTTGACAAGAGATAAAGTCGTTAAAGATACTGGGAAACCGATCTGTGTG
CCAGTCGGTAGACAGACTCTTGGGCGAATCTTTAATGTAGTTGGGGAAATCATAGATGGTGGTGGCCCTGTACCAGAACC
TAATAAAGTTTCTTCGATATATGCAGAGCCTCCTAGGTTTGATATGCAGAGTACCTCCTCTGAAATTTTGGAGACGGGGA
TCAAAGTAATCGACCTACTTGCACCCTATTCCAAGGGAGGTAAGGTTGGTCTCTTTGGTGGTGCAGGAGTTGGAAAGACT
GTCCTTATTATGGAACTTATCAACAATATCGCTAAGGCCTATGGAGGTTTCTCAGTCTTTGCAGGTGTTGGTGAGCGAAC
CAGAGAGGGGAATGATCTTTACAGCGAAATGGTTGAGTCTGGGGTGATCGACAAGGAACATCCTGAGAAATCTAAGGTTG
TCCTGGTTTATGGTCAGATGAACGAGCCTCCTGGTGCACGTGCGAAGGTTGCTATGAGTGCTCTTACCATGGCTGAATAT
TTTCGTGACAAAGAGGGGCAGGATGTGCTTTTCTTTGTGGATAATATCTTTAGATTCACTCAAGCGGGCGCAGAACTTTC
TACTTTGTTGGGAAGAATCCCGTCGGCGGTAGGCTATCAGCCAACCCTTGCAACGGATATGGGAAGGCTTCAGGAGCGTA
TTACCTCCACTAAAAACGGTTCTATTACTTCTGTTCAGGCAATATATGTTCCTGCTGATGACATTACCGACCCGGCTCCG
GCTACCTCTTTTGCTCACCTAGATTCTACAACTGTTCTGTCAAGACAAGTTGCTGAAGCCGGTATATATCCTGCAGTTGA
TGCGCTTGCTTCTAGTGCACAGATTCTTTCTCCGGAAGTGTTAGGTCAAGAACATTACGAAGTTGCACAAAAGGTGAAGG
GAATTCTTCAAAGTTATAAATCCCTTCAAGATATCATTGCGATTTTGGGCATGGAAGAGCTTTCTGAGGAAGATAAGCTT
ACGGTTTATAGGGCAAGAAAAATTGAGAAATTTTTATCTCAGCCGTTTCATGTAGCAGAGGTCTTTACAGGTCAGCCAGG
CAAATTCGTGAGCCTTAAAGATACAATCGCCGGTTTCAAGGAGTTAGTTGAGGGCAAATGTGATGATATGCCTGAAGCTG
CTTTTTATATGGTTGGTAACATGAACGAGGCGAGAGAAAAGGCCATTAGTCTAAGGGAGAAATAG

Upstream 100 bases:

>100_bases
TGTTGGATTTTGTGCAAAGTTGCTGTGTGTCACAGGGATTTGAAAAAGTTTGTGTATACTTTACAATGTGATCCTGAGTG
ATCTCTGAGTAAGTCTTTTG

Downstream 100 bases:

>100_bases
ATGTCCACTTTTGAGCTTGGTATTTTTACTCCTCTTGAGTGCAGAAAGTTACACGTCGTGAGTTTAGGGGGTGATACAGA
TAGTGGGAGATTCGTTGTTC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MPVSIGKIVRVVGPTVDVKFEDGTLPKIENALTCDNNGKILYLEVAQQLGDGIVRAVAMDSTDGLTRDKVVKDTGKPICV
PVGRQTLGRIFNVVGEIIDGGGPVPEPNKVSSIYAEPPRFDMQSTSSEILETGIKVIDLLAPYSKGGKVGLFGGAGVGKT
VLIMELINNIAKAYGGFSVFAGVGERTREGNDLYSEMVESGVIDKEHPEKSKVVLVYGQMNEPPGARAKVAMSALTMAEY
FRDKEGQDVLFFVDNIFRFTQAGAELSTLLGRIPSAVGYQPTLATDMGRLQERITSTKNGSITSVQAIYVPADDITDPAP
ATSFAHLDSTTVLSRQVAEAGIYPAVDALASSAQILSPEVLGQEHYEVAQKVKGILQSYKSLQDIIAILGMEELSEEDKL
TVYRARKIEKFLSQPFHVAEVFTGQPGKFVSLKDTIAGFKELVEGKCDDMPEAAFYMVGNMNEAREKAISLREK

Sequences:

>Translated_474_residues
MPVSIGKIVRVVGPTVDVKFEDGTLPKIENALTCDNNGKILYLEVAQQLGDGIVRAVAMDSTDGLTRDKVVKDTGKPICV
PVGRQTLGRIFNVVGEIIDGGGPVPEPNKVSSIYAEPPRFDMQSTSSEILETGIKVIDLLAPYSKGGKVGLFGGAGVGKT
VLIMELINNIAKAYGGFSVFAGVGERTREGNDLYSEMVESGVIDKEHPEKSKVVLVYGQMNEPPGARAKVAMSALTMAEY
FRDKEGQDVLFFVDNIFRFTQAGAELSTLLGRIPSAVGYQPTLATDMGRLQERITSTKNGSITSVQAIYVPADDITDPAP
ATSFAHLDSTTVLSRQVAEAGIYPAVDALASSAQILSPEVLGQEHYEVAQKVKGILQSYKSLQDIIAILGMEELSEEDKL
TVYRARKIEKFLSQPFHVAEVFTGQPGKFVSLKDTIAGFKELVEGKCDDMPEAAFYMVGNMNEAREKAISLREK
>Mature_473_residues
PVSIGKIVRVVGPTVDVKFEDGTLPKIENALTCDNNGKILYLEVAQQLGDGIVRAVAMDSTDGLTRDKVVKDTGKPICVP
VGRQTLGRIFNVVGEIIDGGGPVPEPNKVSSIYAEPPRFDMQSTSSEILETGIKVIDLLAPYSKGGKVGLFGGAGVGKTV
LIMELINNIAKAYGGFSVFAGVGERTREGNDLYSEMVESGVIDKEHPEKSKVVLVYGQMNEPPGARAKVAMSALTMAEYF
RDKEGQDVLFFVDNIFRFTQAGAELSTLLGRIPSAVGYQPTLATDMGRLQERITSTKNGSITSVQAIYVPADDITDPAPA
TSFAHLDSTTVLSRQVAEAGIYPAVDALASSAQILSPEVLGQEHYEVAQKVKGILQSYKSLQDIIAILGMEELSEEDKLT
VYRARKIEKFLSQPFHVAEVFTGQPGKFVSLKDTIAGFKELVEGKCDDMPEAAFYMVGNMNEAREKAISLREK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=471, Percent_Identity=68.3651804670913, Blast_Score=645, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=368, Percent_Identity=25.8152173913043, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI19913426, Length=442, Percent_Identity=24.4343891402715, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI19913424, Length=303, Percent_Identity=28.0528052805281, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI50345984, Length=322, Percent_Identity=25.1552795031056, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4757810, Length=322, Percent_Identity=25.1552795031056, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1790170, Length=469, Percent_Identity=64.818763326226, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1788251, Length=314, Percent_Identity=30.5732484076433, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790172, Length=309, Percent_Identity=26.537216828479, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144756, Length=469, Percent_Identity=67.8038379530917, Blast_Score=640, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=396, Percent_Identity=26.010101010101, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=383, Percent_Identity=25.065274151436, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=306, Percent_Identity=28.7581699346405, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=319, Percent_Identity=25.0783699059561, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988063, Length=319, Percent_Identity=25.0783699059561, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988074, Length=361, Percent_Identity=23.2686980609418, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=70.0873362445415, Blast_Score=648, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=397, Percent_Identity=25.6926952141058, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=373, Percent_Identity=24.3967828418231, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320016, Length=238, Percent_Identity=26.890756302521, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24638766, Length=466, Percent_Identity=69.7424892703863, Blast_Score=652, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=467, Percent_Identity=66.3811563169165, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI281361666, Length=407, Percent_Identity=25.0614250614251, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646341, Length=407, Percent_Identity=25.0614250614251, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136796, Length=407, Percent_Identity=25.0614250614251, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI20129479, Length=309, Percent_Identity=27.1844660194175, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24583992, Length=308, Percent_Identity=27.9220779220779, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583988, Length=305, Percent_Identity=28.1967213114754, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583986, Length=305, Percent_Identity=28.1967213114754, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583984, Length=305, Percent_Identity=28.1967213114754, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=58.2417582417582, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658560, Length=322, Percent_Identity=25.776397515528, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_NEOSM (Q2GD08)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506638.1
- ProteinModelPortal:   Q2GD08
- SMR:   Q2GD08
- STRING:   Q2GD08
- GeneID:   3931569
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0763
- TIGR:   NSE_0763
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q2GD08
- ProtClustDB:   PRK09280
- BioCyc:   NSEN222891:NSE_0763-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51168; Mature: 51037

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSIGKIVRVVGPTVDVKFEDGTLPKIENALTCDNNGKILYLEVAQQLGDGIVRAVAMD
CCCCHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCCCCEEEHHHHHHHHHHHHHHHEEC
STDGLTRDKVVKDTGKPICVPVGRQTLGRIFNVVGEIIDGGGPVPEPNKVSSIYAEPPRF
CCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCC
DMQSTSSEILETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVLIMELINNIAKAYGGFSVF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHH
AGVGERTREGNDLYSEMVESGVIDKEHPEKSKVVLVYGQMNEPPGARAKVAMSALTMAEY
HCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
FRDKEGQDVLFFVDNIFRFTQAGAELSTLLGRIPSAVGYQPTLATDMGRLQERITSTKNG
HHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCC
SITSVQAIYVPADDITDPAPATSFAHLDSTTVLSRQVAEAGIYPAVDALASSAQILSPEV
CEEEEEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHCHHHCCHHH
LGQEHYEVAQKVKGILQSYKSLQDIIAILGMEELSEEDKLTVYRARKIEKFLSQPFHVAE
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCCEEHH
VFTGQPGKFVSLKDTIAGFKELVEGKCDDMPEAAFYMVGNMNEAREKAISLREK
HHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PVSIGKIVRVVGPTVDVKFEDGTLPKIENALTCDNNGKILYLEVAQQLGDGIVRAVAMD
CCCHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCCCCEEEHHHHHHHHHHHHHHHEEC
STDGLTRDKVVKDTGKPICVPVGRQTLGRIFNVVGEIIDGGGPVPEPNKVSSIYAEPPRF
CCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCC
DMQSTSSEILETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVLIMELINNIAKAYGGFSVF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHH
AGVGERTREGNDLYSEMVESGVIDKEHPEKSKVVLVYGQMNEPPGARAKVAMSALTMAEY
HCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
FRDKEGQDVLFFVDNIFRFTQAGAELSTLLGRIPSAVGYQPTLATDMGRLQERITSTKNG
HHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCC
SITSVQAIYVPADDITDPAPATSFAHLDSTTVLSRQVAEAGIYPAVDALASSAQILSPEV
CEEEEEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHCHHHCCHHH
LGQEHYEVAQKVKGILQSYKSLQDIIAILGMEELSEEDKLTVYRARKIEKFLSQPFHVAE
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCCEEHH
VFTGQPGKFVSLKDTIAGFKELVEGKCDDMPEAAFYMVGNMNEAREKAISLREK
HHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA