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The map label for this gene is groES

Identifier: 88608649

GI number: 88608649

Start: 563368

End: 563664

Strand: Reverse

Name: groES

Synonym: NSE_0643

Alternate gene names: 88608649

Gene position: 563664-563368 (Counterclockwise)

Preceding gene: 88608853

Following gene: 88608250

Centisome position: 65.62

GC content: 42.09

Gene sequence:

>297_bases
ATGAAAGTTGGATTAAAGATGTTACATGATCAGGTCCTTATTAGGCCTCATGAAGAAAAGGATGGTGCTGGTGGGATATA
TATTCCTGATTCAGCAAAGAAGAAGCCAACAATGGGTCTTGTTGTAGCTGTTGGAGCAGGTGCGAAAAACTCAAACGGCA
CTTTTCAGCCTGTGTGTGTCAAAGAGGGAGATATTGTTCTTTACAGAAAATGGGCAGGCAGTGAAGTGGAGCATGACGGT
GTTGAGTACGTCGTGATGAAGGAGACTGATATTATTGCTATTAAGGAGGGTAAATAA

Upstream 100 bases:

>100_bases
ACATGTGATGTAGGTCTTGAAAAATATCACAGCGATTACGATATTTGATTCTGTAGGTCATTAGAATGGTTAATCGAGAT
TGATAGGAGAGAAGATACTT

Downstream 100 bases:

>100_bases
TGGCGAACGAAGTAATAAGTGGTGAACAGTTGCAGAGAGTTATCCGTGATGCAGCTGACTTGGTTGTATCAAGTGCTGGT
GTAACACTTGGGCCTGAGGG

Product: 10 kDa chaperonin

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MKVGLKMLHDQVLIRPHEEKDGAGGIYIPDSAKKKPTMGLVVAVGAGAKNSNGTFQPVCVKEGDIVLYRKWAGSEVEHDG
VEYVVMKETDIIAIKEGK

Sequences:

>Translated_98_residues
MKVGLKMLHDQVLIRPHEEKDGAGGIYIPDSAKKKPTMGLVVAVGAGAKNSNGTFQPVCVKEGDIVLYRKWAGSEVEHDG
VEYVVMKETDIIAIKEGK
>Mature_98_residues
MKVGLKMLHDQVLIRPHEEKDGAGGIYIPDSAKKKPTMGLVVAVGAGAKNSNGTFQPVCVKEGDIVLYRKWAGSEVEHDG
VEYVVMKETDIIAIKEGK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=42.1052631578947, Blast_Score=64, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358317, Length=89, Percent_Identity=44.9438202247191, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_EHRSE (O32605)

Other databases:

- EMBL:   U88092
- ProteinModelPortal:   O32605
- SMR:   O32605
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10621; Mature: 10621

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGLKMLHDQVLIRPHEEKDGAGGIYIPDSAKKKPTMGLVVAVGAGAKNSNGTFQPVCV
CCCCCEEECCEEEEECCCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEEEE
KEGDIVLYRKWAGSEVEHDGVEYVVMKETDIIAIKEGK
CCCCEEEEEECCCCCCCCCCEEEEEEECCCEEEEECCC
>Mature Secondary Structure
MKVGLKMLHDQVLIRPHEEKDGAGGIYIPDSAKKKPTMGLVVAVGAGAKNSNGTFQPVCV
CCCCCEEECCEEEEECCCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEEEE
KEGDIVLYRKWAGSEVEHDGVEYVVMKETDIIAIKEGK
CCCCEEEEEECCCCCCCCCCEEEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9215585