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The map label for this gene is holB [H]

Identifier: 88608630

GI number: 88608630

Start: 311189

End: 311989

Strand: Reverse

Name: holB [H]

Synonym: NSE_0377

Alternate gene names: 88608630

Gene position: 311989-311189 (Counterclockwise)

Preceding gene: 88608503

Following gene: 88608095

Centisome position: 36.32

GC content: 39.2

Gene sequence:

>801_bases
ATGTATAAGGCTCAAAAAAAGGTTCTGCTATCTGGGTACCAAAAGTCTCGTGCGTGGCTTCTTACTGGCCCAGGCTTAGA
TGACATGTTTGAAATTGCGATCAGATACGCAAAGTGGATCCTTAAATCTGATGAAGCAATTGGAGATTTAATGATCATCC
AGGAAAGATCTATCAAAGTCGCTCACATACAAAGGATACACGATTTCCTGAATCTGACCAGCAATTTCTCTAACCAGAAG
ATTATCATCATCAGTCACTTTGAGATAATGACAGCTGGTGCGGCAAACGCACTCTTGAAAGTGCTAGAAGAAGGAAAACA
GACAGCGACACTTATCCTGATAGCTAGATACTTACAGCAAATTACAAATACAGTCCGTTCACGTTGCTTTCACCTTTATT
TTCCACCCTTAAAAGAAAATACAGAAATAGAGAAATTAATTGCGCATTATAAAAATCTCTTAGAAAAATCTATAGGGGAA
GAAGCAAAGGATTCTCTTCCAACTCTAGGCAGACTCGATCGGGGTCTAACAACACAATTCCAGATAGCTCAAAAATTTTC
CGAGGCATCACTAAAGGATCTGCTATGCTTTGCGTTCAACCGGATCATTAAATTTCACCACGGAGTTCTAGAAAAAGAAA
GCTTCTTTGGCGAAAGAACTTTACTAGAAAAATTAGGACAATCAGCCATTTTTTGGCACAACAGGTGGCTGCAAATTAGC
GAGGTACTCTCAACACCCAAAGAGCTTTACATAGAAAAAAATCACCTACTAAGGATTGCACTAACTACAAGGGAGATTTA
G

Upstream 100 bases:

>100_bases
AAGTCTATGCCATGCGGATACCAAAGTCTAATATGCAGCGAATGGACTAAGAAAAAAAACACTGTAGAATCGTGGATGTC
CAGCCCACTACTATTCCTGC

Downstream 100 bases:

>100_bases
GTTTCTCCTTATCAAGCCACCAAGATAATAGACACACGCAGGCCACGCTCACAGCTGACCTTTCCAAAAAACTACTCATA
AAACACTAACTGAAAAGCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MYKAQKKVLLSGYQKSRAWLLTGPGLDDMFEIAIRYAKWILKSDEAIGDLMIIQERSIKVAHIQRIHDFLNLTSNFSNQK
IIIISHFEIMTAGAANALLKVLEEGKQTATLILIARYLQQITNTVRSRCFHLYFPPLKENTEIEKLIAHYKNLLEKSIGE
EAKDSLPTLGRLDRGLTTQFQIAQKFSEASLKDLLCFAFNRIIKFHHGVLEKESFFGERTLLEKLGQSAIFWHNRWLQIS
EVLSTPKELYIEKNHLLRIALTTREI

Sequences:

>Translated_266_residues
MYKAQKKVLLSGYQKSRAWLLTGPGLDDMFEIAIRYAKWILKSDEAIGDLMIIQERSIKVAHIQRIHDFLNLTSNFSNQK
IIIISHFEIMTAGAANALLKVLEEGKQTATLILIARYLQQITNTVRSRCFHLYFPPLKENTEIEKLIAHYKNLLEKSIGE
EAKDSLPTLGRLDRGLTTQFQIAQKFSEASLKDLLCFAFNRIIKFHHGVLEKESFFGERTLLEKLGQSAIFWHNRWLQIS
EVLSTPKELYIEKNHLLRIALTTREI
>Mature_266_residues
MYKAQKKVLLSGYQKSRAWLLTGPGLDDMFEIAIRYAKWILKSDEAIGDLMIIQERSIKVAHIQRIHDFLNLTSNFSNQK
IIIISHFEIMTAGAANALLKVLEEGKQTATLILIARYLQQITNTVRSRCFHLYFPPLKENTEIEKLIAHYKNLLEKSIGE
EAKDSLPTLGRLDRGLTTQFQIAQKFSEASLKDLLCFAFNRIIKFHHGVLEKESFFGERTLLEKLGQSAIFWHNRWLQIS
EVLSTPKELYIEKNHLLRIALTTREI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 30757; Mature: 30757

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKAQKKVLLSGYQKSRAWLLTGPGLDDMFEIAIRYAKWILKSDEAIGDLMIIQERSIKV
CCCHHHHHHHHCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCHH
AHIQRIHDFLNLTSNFSNQKIIIISHFEIMTAGAANALLKVLEEGKQTATLILIARYLQQ
HHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ITNTVRSRCFHLYFPPLKENTEIEKLIAHYKNLLEKSIGEEAKDSLPTLGRLDRGLTTQF
HHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCCCHHH
QIAQKFSEASLKDLLCFAFNRIIKFHHGVLEKESFFGERTLLEKLGQSAIFWHNRWLQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHH
EVLSTPKELYIEKNHLLRIALTTREI
HHHCCHHHHEECCCCEEEEEEECCCC
>Mature Secondary Structure
MYKAQKKVLLSGYQKSRAWLLTGPGLDDMFEIAIRYAKWILKSDEAIGDLMIIQERSIKV
CCCHHHHHHHHCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCHH
AHIQRIHDFLNLTSNFSNQKIIIISHFEIMTAGAANALLKVLEEGKQTATLILIARYLQQ
HHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ITNTVRSRCFHLYFPPLKENTEIEKLIAHYKNLLEKSIGEEAKDSLPTLGRLDRGLTTQF
HHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCCCHHH
QIAQKFSEASLKDLLCFAFNRIIKFHHGVLEKESFFGERTLLEKLGQSAIFWHNRWLQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHH
EVLSTPKELYIEKNHLLRIALTTREI
HHHCCHHHHEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]