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The map label for this gene is gap

Identifier: 88608457

GI number: 88608457

Start: 354191

End: 355207

Strand: Direct

Name: gap

Synonym: NSE_0434

Alternate gene names: 88608457

Gene position: 354191-355207 (Clockwise)

Preceding gene: 88608330

Following gene: 88608445

Centisome position: 41.23

GC content: 41.99

Gene sequence:

>1017_bases
TTGGTTGAACAGATGAGAATAGCAATTAATGGTTTTGGTCGTATAGGTAGGGCCGTTCTAAGGATATTAATAGGTTCTCC
GTGTGATGAATTAGAGATAGTAGCTGTGAATACGCCTAGCGCAGTTGAAAGTTGTCTGCATCTTTTGAGATATGATTCTG
TGCACGGAAAATTTGAGTGTTCGATGTCTTTAGCTGAGGACAACGTAGCTATCCTAAATGGTGTACCAGTTCGATTTTCT
AGCAAGACGGATATATCGCTTCTTGATTGGCGTGCTATAGGTGTTGACATTGTCTTAGAATGTAGCGGGGTTTTTAATTC
TCACACTAAGGCGTCGGGTCACCTTAAGGTTGGTGCGAAAGCTGTTTTAGTTTCTGCACCCGTTTTGGATGCTGATTCTA
TAATAATTTATGGGGTGAATCAGCACGCTTTAACTCCTTCTGATAGAATAATTTCAGTTGGTTCGTGTACCACCAATTGC
CTCGCGCCGCTAATCGAAGTAGTGCATAAGAACTTTGGTGTTGAGGCCGCTTTTATGACTACCATACACTCATATACAAA
TGACCAAAATGTTGTTGACAATAGTCATAGAGATTTACGTCGTGGTAGGGCTTGTGGGACATCAATTATACCGACCACAA
CTGGGGTTACAAAGATTGTAGGGAAAATATTCCCGGAGTTAGCTGGGAAAATTGATGGTGTCGCAGTCAGGGTCCCGACT
CCTAATGTTTCAATGGTGGATTTGACAGTTACCACTTCTAGATCCGTTACTGTTGATGAAGTAAATAGTGCATTTATCAA
AGCAGAATCTTCTTATTTAGGGGGTGTTCTTTCAACTTGTGCTGAACCGCTTGTTTCAGTGGATTTCAACAGGGATCCGC
ATAGTGCGATAGTTGATCTTACTGGCACTTATGTTGTTGAGGGTAGGTTGCTGCGTTTGGGTGCTTGGTATGATAATGAA
TGGGGATTTTCCGCGCGCATGTTGGATGTAGCCAGATTTATCAGCACTAAATTGTAA

Upstream 100 bases:

>100_bases
GATGTGCTGGTTCAAATCCAGTCAAGGGTATTTAGAGTTTTTTAGGTTCCCCTAAGTTTTCCGTTTTATGATTTCTTTGC
TGGTTCCGTGATTTTGTCCT

Downstream 100 bases:

>100_bases
GACCTCGTATCTTCATTCGAGCCGTTCGCGAAATAGTCTGCTTTTGTTATACGCTGATGTAGCAAAAGGGTCGTTTTTGT
GCTTTCAACCAGTTTAGTAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVEQMRIAINGFGRIGRAVLRILIGSPCDELEIVAVNTPSAVESCLHLLRYDSVHGKFECSMSLAEDNVAILNGVPVRFS
SKTDISLLDWRAIGVDIVLECSGVFNSHTKASGHLKVGAKAVLVSAPVLDADSIIIYGVNQHALTPSDRIISVGSCTTNC
LAPLIEVVHKNFGVEAAFMTTIHSYTNDQNVVDNSHRDLRRGRACGTSIIPTTTGVTKIVGKIFPELAGKIDGVAVRVPT
PNVSMVDLTVTTSRSVTVDEVNSAFIKAESSYLGGVLSTCAEPLVSVDFNRDPHSAIVDLTGTYVVEGRLLRLGAWYDNE
WGFSARMLDVARFISTKL

Sequences:

>Translated_338_residues
MVEQMRIAINGFGRIGRAVLRILIGSPCDELEIVAVNTPSAVESCLHLLRYDSVHGKFECSMSLAEDNVAILNGVPVRFS
SKTDISLLDWRAIGVDIVLECSGVFNSHTKASGHLKVGAKAVLVSAPVLDADSIIIYGVNQHALTPSDRIISVGSCTTNC
LAPLIEVVHKNFGVEAAFMTTIHSYTNDQNVVDNSHRDLRRGRACGTSIIPTTTGVTKIVGKIFPELAGKIDGVAVRVPT
PNVSMVDLTVTTSRSVTVDEVNSAFIKAESSYLGGVLSTCAEPLVSVDFNRDPHSAIVDLTGTYVVEGRLLRLGAWYDNE
WGFSARMLDVARFISTKL
>Mature_338_residues
MVEQMRIAINGFGRIGRAVLRILIGSPCDELEIVAVNTPSAVESCLHLLRYDSVHGKFECSMSLAEDNVAILNGVPVRFS
SKTDISLLDWRAIGVDIVLECSGVFNSHTKASGHLKVGAKAVLVSAPVLDADSIIIYGVNQHALTPSDRIISVGSCTTNC
LAPLIEVVHKNFGVEAAFMTTIHSYTNDQNVVDNSHRDLRRGRACGTSIIPTTTGVTKIVGKIFPELAGKIDGVAVRVPT
PNVSMVDLTVTTSRSVTVDEVNSAFIKAESSYLGGVLSTCAEPLVSVDFNRDPHSAIVDLTGTYVVEGRLLRLGAWYDNE
WGFSARMLDVARFISTKL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=40.4761904761905, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI7657116, Length=340, Percent_Identity=39.1176470588235, Blast_Score=242, Evalue=4e-64,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=43.1137724550898, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=39.7590361445783, Blast_Score=257, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17534679, Length=343, Percent_Identity=39.6501457725948, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17534677, Length=343, Percent_Identity=39.3586005830904, Blast_Score=257, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=40.2366863905325, Blast_Score=251, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=40.2366863905325, Blast_Score=251, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=40.8408408408408, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=40.8408408408408, Blast_Score=259, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=39.9399399399399, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=41.9161676646707, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=41.9161676646707, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=41.3173652694611, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=41.3173652694611, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=41.3373860182371, Blast_Score=255, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36373; Mature: 36373

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEQMRIAINGFGRIGRAVLRILIGSPCDELEIVAVNTPSAVESCLHLLRYDSVHGKFEC
CCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEE
SMSLAEDNVAILNGVPVRFSSKTDISLLDWRAIGVDIVLECSGVFNSHTKASGHLKVGAK
EEEECCCCEEEEECCCEEECCCCCCEEEEEEEECEEEEEEECCCCCCCCCCCCEEEECCE
AVLVSAPVLDADSIIIYGVNQHALTPSDRIISVGSCTTNCLAPLIEVVHKNFGVEAAFMT
EEEEECCCCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
TIHSYTNDQNVVDNSHRDLRRGRACGTSIIPTTTGVTKIVGKIFPELAGKIDGVAVRVPT
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
PNVSMVDLTVTTSRSVTVDEVNSAFIKAESSYLGGVLSTCAEPLVSVDFNRDPHSAIVDL
CCCEEEEEEEECCCCEEHHHHCCCEEEECCHHHHHHHHHHHHHHEEEECCCCCCCEEEEE
TGTYVVEGRLLRLGAWYDNEWGFSARMLDVARFISTKL
CCEEEEECEEEEEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEQMRIAINGFGRIGRAVLRILIGSPCDELEIVAVNTPSAVESCLHLLRYDSVHGKFEC
CCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEE
SMSLAEDNVAILNGVPVRFSSKTDISLLDWRAIGVDIVLECSGVFNSHTKASGHLKVGAK
EEEECCCCEEEEECCCEEECCCCCCEEEEEEEECEEEEEEECCCCCCCCCCCCEEEECCE
AVLVSAPVLDADSIIIYGVNQHALTPSDRIISVGSCTTNCLAPLIEVVHKNFGVEAAFMT
EEEEECCCCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
TIHSYTNDQNVVDNSHRDLRRGRACGTSIIPTTTGVTKIVGKIFPELAGKIDGVAVRVPT
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
PNVSMVDLTVTTSRSVTVDEVNSAFIKAESSYLGGVLSTCAEPLVSVDFNRDPHSAIVDL
CCCEEEEEEEECCCCEEHHHHCCCEEEECCHHHHHHHHHHHHHHEEEECCCCCCCEEEEE
TGTYVVEGRLLRLGAWYDNEWGFSARMLDVARFISTKL
CCEEEEECEEEEEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]