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The map label for this gene is pgsA

Identifier: 88608412

GI number: 88608412

Start: 8215

End: 8763

Strand: Reverse

Name: pgsA

Synonym: NSE_0009

Alternate gene names: 88608412

Gene position: 8763-8215 (Counterclockwise)

Preceding gene: 88608689

Following gene: 88608655

Centisome position: 1.02

GC content: 39.16

Gene sequence:

>549_bases
ATGAAGGACCTTCCTAACTTACTTACCGCTTTAAGGATAGCCATTATCCCAGTATTCTGCTTAAGTTTTTATATTCAATC
CAGATTTTCTTGGGTGATAACCGTAGGAATTTTCTCAATCGCAAGTCTGACAGACTTTTTTGACGGGTACCTCGCTAGGA
CGCTAAAGGCTCAATCAAAGCTTGGAAAACTTCTTGACCCGATAGCCGATAAAATGATTGTCTCTACAGCTATTGTTATG
TTGGTACATATGCAGTACATAACGGGAGTCCAACTGATTCCCGCAATCATGATCATTTGTAGAGAGCTGTTTATTGCTGG
ACTAAGGGAATATCTTGCTCGTGACAGTGTGGCATTTCCTGTAAATAGATTTGGTAAACTAAAGACAATATCCCAGATGG
TTGCTATACTTCTTTATCTCCTAAACAAGGAATGGATCCCAGATATTCTTCCGACATTTTTCATCTGGATAGCTGGTCTA
ACGAGCATGGCATCGGCATATTTATATCTTCATGAAAACAAGGAAGAACTACTAAAATCCCTTAGCTAA

Upstream 100 bases:

>100_bases
TGGTCAAGGTCTCACAAAAAACTTTCAAGATCAGCAATTAGGTGGTAGGGTTTGTGGCTGTTAAGGAACCTTTGGACTAT
TCTCTATTGCCATTTTCCCT

Downstream 100 bases:

>100_bases
AAATACTGCTGCCCCAACCCTAGCTGGCTGTCCTATAATCAGGTCGTGATTCTTGGATAGCGAAATGAACATATCAAGTT
TGGTAGCACTCTTATTAAAG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKDLPNLLTALRIAIIPVFCLSFYIQSRFSWVITVGIFSIASLTDFFDGYLARTLKAQSKLGKLLDPIADKMIVSTAIVM
LVHMQYITGVQLIPAIMIICRELFIAGLREYLARDSVAFPVNRFGKLKTISQMVAILLYLLNKEWIPDILPTFFIWIAGL
TSMASAYLYLHENKEELLKSLS

Sequences:

>Translated_182_residues
MKDLPNLLTALRIAIIPVFCLSFYIQSRFSWVITVGIFSIASLTDFFDGYLARTLKAQSKLGKLLDPIADKMIVSTAIVM
LVHMQYITGVQLIPAIMIICRELFIAGLREYLARDSVAFPVNRFGKLKTISQMVAILLYLLNKEWIPDILPTFFIWIAGL
TSMASAYLYLHENKEELLKSLS
>Mature_182_residues
MKDLPNLLTALRIAIIPVFCLSFYIQSRFSWVITVGIFSIASLTDFFDGYLARTLKAQSKLGKLLDPIADKMIVSTAIVM
LVHMQYITGVQLIPAIMIICRELFIAGLREYLARDSVAFPVNRFGKLKTISQMVAILLYLLNKEWIPDILPTFFIWIAGL
TSMASAYLYLHENKEELLKSLS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=188, Percent_Identity=38.8297872340425, Blast_Score=110, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6320059, Length=107, Percent_Identity=35.5140186915888, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20626; Mature: 20626

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLPNLLTALRIAIIPVFCLSFYIQSRFSWVITVGIFSIASLTDFFDGYLARTLKAQSK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKLLDPIADKMIVSTAIVMLVHMQYITGVQLIPAIMIICRELFIAGLREYLARDSVAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNRFGKLKTISQMVAILLYLLNKEWIPDILPTFFIWIAGLTSMASAYLYLHENKEELLKS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LS
CC
>Mature Secondary Structure
MKDLPNLLTALRIAIIPVFCLSFYIQSRFSWVITVGIFSIASLTDFFDGYLARTLKAQSK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKLLDPIADKMIVSTAIVMLVHMQYITGVQLIPAIMIICRELFIAGLREYLARDSVAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNRFGKLKTISQMVAILLYLLNKEWIPDILPTFFIWIAGLTSMASAYLYLHENKEELLKS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA