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The map label for this gene is nuoN [H]

Identifier: 88608391

GI number: 88608391

Start: 625046

End: 626422

Strand: Direct

Name: nuoN [H]

Synonym: NSE_0706

Alternate gene names: 88608391

Gene position: 625046-626422 (Clockwise)

Preceding gene: 88607973

Following gene: 88608002

Centisome position: 72.76

GC content: 42.48

Gene sequence:

>1377_bases
ATGTACCAAACTCTTTTAATCCTAGAGGTGATTTCACCACTGCTTGCCGCGCTCCTGTTAATCTTCTCAAATGCGAAAGT
CTATAAGCGTACGCTCTTGCCTATCGCACAGACGTTTGGTGTTGGCAGCTCAATCGCGATATTTGCACACACCTCACAAG
GAATAAGAATATCACTCACGGTTGGTGGATGGGACTCCATCTACGGAATCGAAGTTGCAGCCAATCACTACACGGCAATT
ATGCTACTTCTCCTCAATACGGTCACAGCCCTGACGGTACTGCACTCATTCCAGAAAGATAGAGAAAGTTTTTTCTACAG
CATCTTGATGCTGTGTCATGCTGGTCTCTCGGGGATGGTAATATCGAACGATCTATTCAATATTTATGTCTTTCTCGAAC
TGTCCTCACTCGCAAGCTACACGCTTGTTGCGACTAAAGGTACACAAGAATCATATAAAGCAGCATTTGAATATCTGATA
ATCGGAACAATTTCTGCAACGTTCTACTTGATTGGAATCGGACTCATATACGCAGTCACTGGACACCTAAATGTTGGAAT
CATCACCTCCATGTCAGACATAATACTGAGTTCACATATCGGTAGGGCAGGTGCAACGCTCGTAGTACTTGGCATAATAG
GCAAATGCGCTTTATTTCCTCTACATTTCTGGTTGGTACGTTGTTATAGTTCTACAAGCACAACCGTAGCAGCATTTTTG
TCGGGAGTGAGCTCAAAAGTCGGGCTGTATCTATTGGCTAAGTTTGTGTACACAATTATTGGTGCACGTGTCTTAGTCCT
TTCTGGATTTCCTTTGAATATAGTGATACTGGTTTTAAGTACATTAGCAATTTTCGTATGCGGTCTGCAGGCAATAACAA
CACAGGATGTAAGGCAAATGCTCAGCTACTCCAGCATTTCACAAATTGGTTACATCTCCTTGACACTTTCACTTGGATCT
GATTACTCCGTTTCAGTTGCAATGCTCCAGATGCTTGCACACGCAGTAACCAAATCAGGGCTGTTCATGCTAGCCGGAGG
AGCAATACATCAGACTGAAAGAAGACACAAGCAGTCAGCCATGAGAAAGATCTATCTTCTTGTTGCGACACTCAGCTTAG
CTGGAATCCCCCTGACATCAGGATTTCTAGGAAAGCTCGAGCTCCTTCTTCTCACGGTACACATGCACCACTATTTAACT
CTGTTGATCCTGATAATTGGAAGCATTATCACTGCAATCTATAGCTGGAAGATTTTCAATGCATTACATAAATTTGAAGC
AGGAAATTCGATCCTATATCACATATCAATGTCGGCGCTCTCTCTGATAAACATTGCCATTCCATTAACAAGTGGATTCT
TTTTGAAACTAATTTAG

Upstream 100 bases:

>100_bases
TAGGAGTCACTGATTTTAGAGAGTGTAGCGGTGGACATAAGTATATTGCTTCTCAAAGTTGATTTAACATATCGCACATG
CAAGAAGAGTTGATCTAAGA

Downstream 100 bases:

>100_bases
CTGTCTAAGAGCCTGATCCAGATCCTTAGGAAAAGGCTGGGATCCCTCAGCGCCTAATCTTCTCAAATGGATCAGAATTG
ACACAATTGCAGCAGGTGTA

Product: NADH-ubiquinone/plastoquinone oxidoreductase family protein

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MYQTLLILEVISPLLAALLLIFSNAKVYKRTLLPIAQTFGVGSSIAIFAHTSQGIRISLTVGGWDSIYGIEVAANHYTAI
MLLLLNTVTALTVLHSFQKDRESFFYSILMLCHAGLSGMVISNDLFNIYVFLELSSLASYTLVATKGTQESYKAAFEYLI
IGTISATFYLIGIGLIYAVTGHLNVGIITSMSDIILSSHIGRAGATLVVLGIIGKCALFPLHFWLVRCYSSTSTTVAAFL
SGVSSKVGLYLLAKFVYTIIGARVLVLSGFPLNIVILVLSTLAIFVCGLQAITTQDVRQMLSYSSISQIGYISLTLSLGS
DYSVSVAMLQMLAHAVTKSGLFMLAGGAIHQTERRHKQSAMRKIYLLVATLSLAGIPLTSGFLGKLELLLLTVHMHHYLT
LLILIIGSIITAIYSWKIFNALHKFEAGNSILYHISMSALSLINIAIPLTSGFFLKLI

Sequences:

>Translated_458_residues
MYQTLLILEVISPLLAALLLIFSNAKVYKRTLLPIAQTFGVGSSIAIFAHTSQGIRISLTVGGWDSIYGIEVAANHYTAI
MLLLLNTVTALTVLHSFQKDRESFFYSILMLCHAGLSGMVISNDLFNIYVFLELSSLASYTLVATKGTQESYKAAFEYLI
IGTISATFYLIGIGLIYAVTGHLNVGIITSMSDIILSSHIGRAGATLVVLGIIGKCALFPLHFWLVRCYSSTSTTVAAFL
SGVSSKVGLYLLAKFVYTIIGARVLVLSGFPLNIVILVLSTLAIFVCGLQAITTQDVRQMLSYSSISQIGYISLTLSLGS
DYSVSVAMLQMLAHAVTKSGLFMLAGGAIHQTERRHKQSAMRKIYLLVATLSLAGIPLTSGFLGKLELLLLTVHMHHYLT
LLILIIGSIITAIYSWKIFNALHKFEAGNSILYHISMSALSLINIAIPLTSGFFLKLI
>Mature_458_residues
MYQTLLILEVISPLLAALLLIFSNAKVYKRTLLPIAQTFGVGSSIAIFAHTSQGIRISLTVGGWDSIYGIEVAANHYTAI
MLLLLNTVTALTVLHSFQKDRESFFYSILMLCHAGLSGMVISNDLFNIYVFLELSSLASYTLVATKGTQESYKAAFEYLI
IGTISATFYLIGIGLIYAVTGHLNVGIITSMSDIILSSHIGRAGATLVVLGIIGKCALFPLHFWLVRCYSSTSTTVAAFL
SGVSSKVGLYLLAKFVYTIIGARVLVLSGFPLNIVILVLSTLAIFVCGLQAITTQDVRQMLSYSSISQIGYISLTLSLGS
DYSVSVAMLQMLAHAVTKSGLFMLAGGAIHQTERRHKQSAMRKIYLLVATLSLAGIPLTSGFLGKLELLLLTVHMHHYLT
LLILIIGSIITAIYSWKIFNALHKFEAGNSILYHISMSALSLINIAIPLTSGFFLKLI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=364, Percent_Identity=27.1978021978022, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788831, Length=287, Percent_Identity=27.8745644599303, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788614, Length=464, Percent_Identity=24.7844827586207, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788613, Length=380, Percent_Identity=25, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788827, Length=303, Percent_Identity=26.4026402640264, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788829, Length=315, Percent_Identity=24.4444444444444, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49658; Mature: 49658

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQTLLILEVISPLLAALLLIFSNAKVYKRTLLPIAQTFGVGSSIAIFAHTSQGIRISLT
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEE
VGGWDSIYGIEVAANHYTAIMLLLLNTVTALTVLHSFQKDRESFFYSILMLCHAGLSGMV
ECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ISNDLFNIYVFLELSSLASYTLVATKGTQESYKAAFEYLIIGTISATFYLIGIGLIYAVT
EECCCEEEEEEEEEHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHLNVGIITSMSDIILSSHIGRAGATLVVLGIIGKCALFPLHFWLVRCYSSTSTTVAAFL
CCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGVSSKVGLYLLAKFVYTIIGARVLVLSGFPLNIVILVLSTLAIFVCGLQAITTQDVRQM
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYSSISQIGYISLTLSLGSDYSVSVAMLQMLAHAVTKSGLFMLAGGAIHQTERRHKQSA
HHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHH
MRKIYLLVATLSLAGIPLTSGFLGKLELLLLTVHMHHYLTLLILIIGSIITAIYSWKIFN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALHKFEAGNSILYHISMSALSLINIAIPLTSGFFLKLI
HHHHHCCCCEEEEEEHHHHHHHHHHEEECCCCEEEEEC
>Mature Secondary Structure
MYQTLLILEVISPLLAALLLIFSNAKVYKRTLLPIAQTFGVGSSIAIFAHTSQGIRISLT
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEE
VGGWDSIYGIEVAANHYTAIMLLLLNTVTALTVLHSFQKDRESFFYSILMLCHAGLSGMV
ECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ISNDLFNIYVFLELSSLASYTLVATKGTQESYKAAFEYLIIGTISATFYLIGIGLIYAVT
EECCCEEEEEEEEEHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHLNVGIITSMSDIILSSHIGRAGATLVVLGIIGKCALFPLHFWLVRCYSSTSTTVAAFL
CCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGVSSKVGLYLLAKFVYTIIGARVLVLSGFPLNIVILVLSTLAIFVCGLQAITTQDVRQM
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYSSISQIGYISLTLSLGSDYSVSVAMLQMLAHAVTKSGLFMLAGGAIHQTERRHKQSA
HHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHH
MRKIYLLVATLSLAGIPLTSGFLGKLELLLLTVHMHHYLTLLILIIGSIITAIYSWKIFN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALHKFEAGNSILYHISMSALSLINIAIPLTSGFFLKLI
HHHHHCCCCEEEEEEHHHHHHHHHHEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA