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The map label for this gene is rpoB

Identifier: 88608380

GI number: 88608380

Start: 598275

End: 602351

Strand: Reverse

Name: rpoB

Synonym: NSE_0678

Alternate gene names: 88608380

Gene position: 602351-598275 (Counterclockwise)

Preceding gene: 88608716

Following gene: 88608346

Centisome position: 70.12

GC content: 43.41

Gene sequence:

>4077_bases
ATGTCTGAATTTCACAGGTTATACTTCGATGAGCTGCTTTTTGACTTTCCTGATCTGGTGAAAGTCCAAAAGGATTCTTA
TGCTTCGTTTGTAGGTGGAGGTGATACTGTATTTTCAATCAGCGATATTTTTGCATCCGTTTTTCCGGTGAATGATGGAT
ATGGTAGGGCTTCCCTTGAGTTTGTGAGCTGCAGGATGGGTGAGCCTAAGCATGACGAATATGGCTGTGTTGAAAGAGGT
ATTACGTACTCGGCGCCGCTCAGGGCAATACTTAGGCTAGTTGTTTTTGGTGATGAGACATCTGGCGAAGGTAGTGAGGG
GGTGTCAACTGAACCAGCGGTAAAGGATGTACGAGAACAGGAGATATACATGGGTGACATACCCATTATGTCTAAGAACG
GGACGTTCATAATAAATGGTGTGGAAAGGGTTGTCGTATCTCAGATGCATCGTGCACCTGGGGTGTTTTTCGATAATGAC
AAAGCTAGGTCAATCTCCGGCAAGCTCAATTATATTGCGCGTATCATACCTTATAGGGGTTCTTGGTTGGACTTTGAGTT
TGATGCTAAGGACGTATTGTATTTTCGAATAGATAAAAAGAGAAAACTTCCAGTCACTTTTTTGCTTAGGGCTCTGGGGT
TGTCGAATAAGGATATTTTTGCTCAGTTTTGTGAGGTCTCGGAGTGTCGCTTAACGAAAGATGGTAAGTGGACTGTTTGC
TTTGTTCCGGAAAAGTTTAAGGGGGTTCGTCTTCAGTATGATCTTATCAATGCGGAGACAGGTGAGTTAGTTTTGGCAAA
GGGCAACAGGATTTCCATAGTATTGGCGCGAAATCTATATGCGAAAGGGTTACGTTATTGCTACATGGACTTAGAAGTCA
TGAAGGACATGTACCTTGCTGATGATCTTGTCTCGACTAAAGGAGAAGTTCTTCTTCCACATGGTACGAAGTTGACCAAG
GAGCATGTTGCAAAGTTGGAATTTCTTGATGTGGATTCTATTAAGTTGGTTGAACTGAAGGGTAATTATGTATTCAGTAC
TGTTTTGCAGTACGATTGCTCTTATGAAGAAGCAATGCTCTCGATATATAGAGTTGTTCGGCCAGGTGAGATTCCTTCTG
TTGAGTCTGCAGAGAAGCTGTTTGAGTCGCTCTTTTTTTCTCCTGAGAGGTACGATCTCCTGAACGTCGGTAGGATCAGG
CTAAATGCCAAGTTTAATCTAAGTCATGATGAGAGTCTGACTGTTTTGACTAAGGAGGACATTTTTTGCACGGTAAAGGA
GTTGGCCCTTTTACAAAGAGAAGTTGGGGACGTCGATGACATAGATCATCTTGGCAATAGGCGGGTTAGGTCTGTTGGGG
AGTTTATGGATAATCAGTTCCGCATCGGGCTTGTGAGGATGGCCAAGGTTATTGTCGAAAATATGGCGACTGCCGACTTT
GATACGGTGATGCCGTGTGAAATGATAAATTCTAAGATTCTTGGGGCTGTCATTCGTGAATTTTTCATGTCTTCGGCACT
TTCGCAGTTTATGGATCAGACTAACCCACTCTCGGAAATTACGCATAAACGCCGTATATCAGCTTTAGGTCCTGGGGGAT
TGAATAGAGGTAGGGCGGGATTCGAGGTGCGAGATGTGCATACCACGCATTACGGTAGGATCTGTGCAACGGAGACCCCG
GAAGGTGCGACTATTGGGCTGATAAATAGTCTTGCTATATATGCAAAGATTAATAAGTATGGCTTTATAGAGACCCCCTA
CCGCTATGTGCGTGATGGCCGTGTTACCGACGAAGTCACATATCTTTCTGCGATCGATGAAATAAAGGCAAATATTTGTC
AAGCTAGTGTTCGTGTCGATGAAGAAGGCTATATAGTCGACGATTTGGTGTACTGTCGTAGGAATTATGAGAATGTTTTT
ATTCCGCGTAGTGAGGTTCAGTTTGCGGATGTATCGGCTAAGCAAATAGTCTCGGTTGCTGCCTCTTTAATTCCTTTTCT
GGAAAATGATGATGCAAATAGAGCTCTCATGGGTTCCAACATGCAAAGACAAGCTGTACCACTTATCATGCCTGAGGCAC
CATTGGTTGGGACTGGGATGGAAGGCTATGTAGCGCGTGGTTCTGGTGCCGTAATAGTTGCCAAACGTGCAGGTGTTGTG
CAGTATATAGATGCCAGGAATATCGTTGTTGCGTCGGAGTCGAAGGACGATTTCTGGATTGATTCTTATACGTTGTGTAA
ATTCAGAAAGTCGAATCACAATACATGTATACATCAGCGTTGTGTTGTCCATCAGGGACAGCGTGTTAAAAAAGGTGATA
TTCTTGCTGATGGACCAGCGATTCAAAAGGGTGAACTAGCTCTTGGAAGGAATTTGGTGGTGGCTTTTCTCTCGTGGCGT
GGCTACAACTTTGAGGATTCCGTTGTCATTTCAAGTAATGTTGTCCGTGATGATCTTTTCACTTCAGTGCATTTAGAAGG
TTTTGAATGTGTTGTTCGCGATACAAGGTTAGGTCCTGAGGAAATAACAAGGGATGTTTCTGGTGTGGCAGAAGAGTTTT
TACACTGTCTTGATGAGTTTGGCATAGCATGTGTTGGGGCAAACGTCGAGGCTGGAGATGTTCTGGTAGGAAAGGTGACG
CCTAAAAGTAGTTCACCTGTGACACCCGAAGAAAAGTTGCTTCGTGCTATATTTGGAGAGAAAGCGATTGATGTGAAAGA
TTCGTCTCTGTACTTACCACCTGGTGTATCTGGTTGTGTAGTGGATGTAAAAGTACTGCAGCGTCGGGGTATAGAAAAGG
TTGGTAGGGCATTGTTAATAGAGAAACAGGCGATCGATGCCGAAAAAACGAGGCGTGACCATGAGCTTGCGGTGTTGACG
AACTATATTTACTCGCTCCTGAAGGAGATGCTGGTTGGTAAGGTTGCTCTTAGTACTTTAGCACCAATCTCAAAGGGTGA
TTTGATTACAGAAGAGGCTCTTGAAAAGATAGATAGGGAGAATTGGTGGAAGATTAGTGTTGATGGAATCTCTTCGATAA
AGCTTTTGAGGCAAAGGTTTGTTGATCGCTTTGACGAAATTAACAAGACCTATGAGGAGAATTTCGAAAAAATTCGAGGT
GATGATGATTTGGCGCAGGGTGTCCTGATGGTGGTAAAGGTTTTTGTCGCTGTGAAGCATACCCTTCAACCAGGTGATAA
GATGTCTGGTAGGCATGGAAATAAGGGTGTTATTTCCAGGATAGTCCCAGCTGAGGATATGCCTTACTTAGCTGATGGTA
CGCCTGTGGATATCATACTTAACCCTTTGGGTGTGCCTTCAAGAATGAATGTGGGTCAAATTCTCGAGACACATCTTGGT
TGGGCTGCATACAATTTGGGTAAGAAAATCTCGAAATTGCTTGATGAAGGTAACTACTCTGAGGTGAAGTCATTGGTTCT
TGAGATTTACAAGAACGATAGGAAAATGATGGCAAGACTTAATGAGATGACGGATGCTGAAATAGTCGAGTATTCGCGTT
CTTTGAGAGGCGGAGTTCCTGTTGCGGCTTCGGTTTTTGAAGGTCCTAAAACAGACGAGATAGAAAGGCTGTTAGTTCTC
GCAGGAAAAGATCCTTCGGGTCAGGAAGTCTTGTATGATGGTGTAACTGGAGAGAAGTTTGATAGGAAGGTCACTGTTGG
GTGTAAGTATATGCTGAAGTTACATCACTTAGTGAATGATAAGATTCATGCGCGTTCTATCGGTTCCTACAGTTTGATAA
CGCAGCAACCACTCGGAGGAAAATCACATTTTGGTGGACAGCGTTTTGGTGAGATGGAATGCTGGGCGTTGCAAGCTTAT
GGTGCAACATTTGCATTACAGGAGATGCTTACTATCAAATCTGACGATGTGGTAGGTCGCGTCAATGTATATGATTCGAT
AGTGCGTGGTGATAATGATTTTTATTATGGTGTTCCCGAGTCCTTTAATGTAATGATGAATGAGTTAAGGGCCTTATGTT
TGAACGTGGAGTTTTGTTCCGATTTGGAAAAAAAGAAAGATTTTGGTGATCTTGCATTAGCAGCATCGGGACAATAG

Upstream 100 bases:

>100_bases
GGCTGATGCATATGCAAAGATCTTAAAGGAAGCTGAATGTGAGCCTGAATTGAAAGGAGAATAACTCTTCTGCGTAGATC
GTTTTCTTGTTTCTTCTCTT

Downstream 100 bases:

>100_bases
GTGGTTAAAAAGAATATTTGCTTTCGGTTTCTATAGGGGTGGTCCTTTTTGTTTATGGGAGATTTTAGGAGTTTTCGCCA
GAATGGGGGCAGCTCGGTTG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1358; Mature: 1357

Protein sequence:

>1358_residues
MSEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDTVFSISDIFASVFPVNDGYGRASLEFVSCRMGEPKHDEYGCVERG
ITYSAPLRAILRLVVFGDETSGEGSEGVSTEPAVKDVREQEIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDND
KARSISGKLNYIARIIPYRGSWLDFEFDAKDVLYFRIDKKRKLPVTFLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVC
FVPEKFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLADDLVSTKGEVLLPHGTKLTK
EHVAKLEFLDVDSIKLVELKGNYVFSTVLQYDCSYEEAMLSIYRVVRPGEIPSVESAEKLFESLFFSPERYDLLNVGRIR
LNAKFNLSHDESLTVLTKEDIFCTVKELALLQREVGDVDDIDHLGNRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADF
DTVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAGFEVRDVHTTHYGRICATETP
EGATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVTYLSAIDEIKANICQASVRVDEEGYIVDDLVYCRRNYENVF
IPRSEVQFADVSAKQIVSVAASLIPFLENDDANRALMGSNMQRQAVPLIMPEAPLVGTGMEGYVARGSGAVIVAKRAGVV
QYIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVHQGQRVKKGDILADGPAIQKGELALGRNLVVAFLSWR
GYNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPEEITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVT
PKSSSPVTPEEKLLRAIFGEKAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKTRRDHELAVLT
NYIYSLLKEMLVGKVALSTLAPISKGDLITEEALEKIDRENWWKISVDGISSIKLLRQRFVDRFDEINKTYEENFEKIRG
DDDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISRIVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLG
WAAYNLGKKISKLLDEGNYSEVKSLVLEIYKNDRKMMARLNEMTDAEIVEYSRSLRGGVPVAASVFEGPKTDEIERLLVL
AGKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGGKSHFGGQRFGEMECWALQAY
GATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPESFNVMMNELRALCLNVEFCSDLEKKKDFGDLALAASGQ

Sequences:

>Translated_1358_residues
MSEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDTVFSISDIFASVFPVNDGYGRASLEFVSCRMGEPKHDEYGCVERG
ITYSAPLRAILRLVVFGDETSGEGSEGVSTEPAVKDVREQEIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDND
KARSISGKLNYIARIIPYRGSWLDFEFDAKDVLYFRIDKKRKLPVTFLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVC
FVPEKFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLADDLVSTKGEVLLPHGTKLTK
EHVAKLEFLDVDSIKLVELKGNYVFSTVLQYDCSYEEAMLSIYRVVRPGEIPSVESAEKLFESLFFSPERYDLLNVGRIR
LNAKFNLSHDESLTVLTKEDIFCTVKELALLQREVGDVDDIDHLGNRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADF
DTVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAGFEVRDVHTTHYGRICATETP
EGATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVTYLSAIDEIKANICQASVRVDEEGYIVDDLVYCRRNYENVF
IPRSEVQFADVSAKQIVSVAASLIPFLENDDANRALMGSNMQRQAVPLIMPEAPLVGTGMEGYVARGSGAVIVAKRAGVV
QYIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVHQGQRVKKGDILADGPAIQKGELALGRNLVVAFLSWR
GYNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPEEITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVT
PKSSSPVTPEEKLLRAIFGEKAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKTRRDHELAVLT
NYIYSLLKEMLVGKVALSTLAPISKGDLITEEALEKIDRENWWKISVDGISSIKLLRQRFVDRFDEINKTYEENFEKIRG
DDDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISRIVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLG
WAAYNLGKKISKLLDEGNYSEVKSLVLEIYKNDRKMMARLNEMTDAEIVEYSRSLRGGVPVAASVFEGPKTDEIERLLVL
AGKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGGKSHFGGQRFGEMECWALQAY
GATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPESFNVMMNELRALCLNVEFCSDLEKKKDFGDLALAASGQ
>Mature_1357_residues
SEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDTVFSISDIFASVFPVNDGYGRASLEFVSCRMGEPKHDEYGCVERGI
TYSAPLRAILRLVVFGDETSGEGSEGVSTEPAVKDVREQEIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDNDK
ARSISGKLNYIARIIPYRGSWLDFEFDAKDVLYFRIDKKRKLPVTFLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVCF
VPEKFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLADDLVSTKGEVLLPHGTKLTKE
HVAKLEFLDVDSIKLVELKGNYVFSTVLQYDCSYEEAMLSIYRVVRPGEIPSVESAEKLFESLFFSPERYDLLNVGRIRL
NAKFNLSHDESLTVLTKEDIFCTVKELALLQREVGDVDDIDHLGNRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADFD
TVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAGFEVRDVHTTHYGRICATETPE
GATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVTYLSAIDEIKANICQASVRVDEEGYIVDDLVYCRRNYENVFI
PRSEVQFADVSAKQIVSVAASLIPFLENDDANRALMGSNMQRQAVPLIMPEAPLVGTGMEGYVARGSGAVIVAKRAGVVQ
YIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVHQGQRVKKGDILADGPAIQKGELALGRNLVVAFLSWRG
YNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPEEITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVTP
KSSSPVTPEEKLLRAIFGEKAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKTRRDHELAVLTN
YIYSLLKEMLVGKVALSTLAPISKGDLITEEALEKIDRENWWKISVDGISSIKLLRQRFVDRFDEINKTYEENFEKIRGD
DDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISRIVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLGW
AAYNLGKKISKLLDEGNYSEVKSLVLEIYKNDRKMMARLNEMTDAEIVEYSRSLRGGVPVAASVFEGPKTDEIERLLVLA
GKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGGKSHFGGQRFGEMECWALQAYG
ATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPESFNVMMNELRALCLNVEFCSDLEKKKDFGDLALAASGQ

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=264, Percent_Identity=30.6818181818182, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI212286172, Length=264, Percent_Identity=30.6818181818182, Blast_Score=125, Evalue=4e-28,
Organism=Homo sapiens, GI4505941, Length=233, Percent_Identity=33.0472103004292, Blast_Score=115, Evalue=4e-25,
Organism=Homo sapiens, GI238908505, Length=252, Percent_Identity=32.9365079365079, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI238908503, Length=252, Percent_Identity=32.9365079365079, Blast_Score=109, Evalue=2e-23,
Organism=Escherichia coli, GI1790419, Length=1348, Percent_Identity=50.8160237388724, Blast_Score=1320, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=244, Percent_Identity=32.3770491803279, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17506623, Length=231, Percent_Identity=31.6017316017316, Blast_Score=114, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25144348, Length=243, Percent_Identity=31.6872427983539, Blast_Score=109, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324725, Length=320, Percent_Identity=30.9375, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324781, Length=245, Percent_Identity=33.8775510204082, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6325267, Length=98, Percent_Identity=42.8571428571429, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17647877, Length=245, Percent_Identity=32.6530612244898, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136446, Length=262, Percent_Identity=31.2977099236641, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17136444, Length=233, Percent_Identity=31.3304721030043, Blast_Score=104, Evalue=3e-22,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 151786; Mature: 151655

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDTVFSISDIFASVFPVNDGYGRASLE
CCHHHHHHHHHHHHCCHHHHHHCCCCHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCEEE
FVSCRMGEPKHDEYGCVERGITYSAPLRAILRLVVFGDETSGEGSEGVSTEPAVKDVREQ
EEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
EIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDNDKARSISGKLNYIARIIPYRG
HEEECCCEEEECCCCEEECCHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHEEECCCC
SWLDFEFDAKDVLYFRIDKKRKLPVTFLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVC
CEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHCEECCCCCEEEE
FVPEKFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLA
ECCCCCCCEEEEEEEECCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
DDLVSTKGEVLLPHGTKLTKEHVAKLEFLDVDSIKLVELKGNYVFSTVLQYDCSYEEAML
HHHHCCCCCEEECCCCCHHHHHHHHEEEECCCCEEEEEECCCEEEEEHHHHCCCHHHHHH
SIYRVVRPGEIPSVESAEKLFESLFFSPERYDLLNVGRIRLNAKFNLSHDESLTVLTKED
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCEEEEEEEEECCCCCCEEEEECCC
IFCTVKELALLQREVGDVDDIDHLGNRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADF
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
DTVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
FEVRDVHTTHYGRICATETPEGATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVT
CEEEEECCCCCCEEEECCCCCCCEEEHHHHEEEEEEECCCCCCCCCHHHHHCCCCCHHHH
YLSAIDEIKANICQASVRVDEEGYIVDDLVYCRRNYENVFIPRSEVQFADVSAKQIVSVA
HHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCEEEECCCCCEECCCCHHHHHHHH
ASLIPFLENDDANRALMGSNMQRQAVPLIMPEAPLVGTGMEGYVARGSGAVIVAKRAGVV
HHHHHHHCCCCCCCHHHCCCCCCCCCCEEECCCCEECCCCCCEEECCCCEEEEEECCCEE
QYIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVHQGQRVKKGDILADGPA
EEECCCCEEEEECCCCCEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEECCCC
IQKGELALGRNLVVAFLSWRGYNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPE
CCCCCHHHCCCEEEEEEHHCCCCCCCCEEEECCHHHHHHHHHEECCCEEEEEECCCCCHH
EITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVTPKSSSPVTPEEKLLRAIFGE
HHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCC
KAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKTRRDHELAVLT
CCCCCCCCCEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHH
NYIYSLLKEMLVGKVALSTLAPISKGDLITEEALEKIDRENWWKISVDGISSIKLLRQRF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
VDRFDEINKTYEENFEKIRGDDDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
IVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLGWAAYNLGKKISKLLDEGNYS
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EVKSLVLEIYKNDRKMMARLNEMTDAEIVEYSRSLRGGVPVAASVFEGPKTDEIERLLVL
HHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHCCCCCCHHHEEEEEE
AGKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGG
ECCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCC
KSHFGGQRFGEMECWALQAYGATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPE
CCCCCCCCCCCCEEEEEEHHCHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEECCCH
SFNVMMNELRALCLNVEFCSDLEKKKDFGDLALAASGQ
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure 
SEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDTVFSISDIFASVFPVNDGYGRASLE
CHHHHHHHHHHHHCCHHHHHHCCCCHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCEEE
FVSCRMGEPKHDEYGCVERGITYSAPLRAILRLVVFGDETSGEGSEGVSTEPAVKDVREQ
EEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
EIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDNDKARSISGKLNYIARIIPYRG
HEEECCCEEEECCCCEEECCHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHEEECCCC
SWLDFEFDAKDVLYFRIDKKRKLPVTFLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVC
CEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHCEECCCCCEEEE
FVPEKFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLA
ECCCCCCCEEEEEEEECCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
DDLVSTKGEVLLPHGTKLTKEHVAKLEFLDVDSIKLVELKGNYVFSTVLQYDCSYEEAML
HHHHCCCCCEEECCCCCHHHHHHHHEEEECCCCEEEEEECCCEEEEEHHHHCCCHHHHHH
SIYRVVRPGEIPSVESAEKLFESLFFSPERYDLLNVGRIRLNAKFNLSHDESLTVLTKED
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCEEEEEEEEECCCCCCEEEEECCC
IFCTVKELALLQREVGDVDDIDHLGNRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADF
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
DTVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
FEVRDVHTTHYGRICATETPEGATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVT
CEEEEECCCCCCEEEECCCCCCCEEEHHHHEEEEEEECCCCCCCCCHHHHHCCCCCHHHH
YLSAIDEIKANICQASVRVDEEGYIVDDLVYCRRNYENVFIPRSEVQFADVSAKQIVSVA
HHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCEEEECCCCCEECCCCHHHHHHHH
ASLIPFLENDDANRALMGSNMQRQAVPLIMPEAPLVGTGMEGYVARGSGAVIVAKRAGVV
HHHHHHHCCCCCCCHHHCCCCCCCCCCEEECCCCEECCCCCCEEECCCCEEEEEECCCEE
QYIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVHQGQRVKKGDILADGPA
EEECCCCEEEEECCCCCEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEECCCC
IQKGELALGRNLVVAFLSWRGYNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPE
CCCCCHHHCCCEEEEEEHHCCCCCCCCEEEECCHHHHHHHHHEECCCEEEEEECCCCCHH
EITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVTPKSSSPVTPEEKLLRAIFGE
HHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCC
KAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKTRRDHELAVLT
CCCCCCCCCEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHH
NYIYSLLKEMLVGKVALSTLAPISKGDLITEEALEKIDRENWWKISVDGISSIKLLRQRF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
VDRFDEINKTYEENFEKIRGDDDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
IVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLGWAAYNLGKKISKLLDEGNYS
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EVKSLVLEIYKNDRKMMARLNEMTDAEIVEYSRSLRGGVPVAASVFEGPKTDEIERLLVL
HHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHCCCCCCHHHEEEEEE
AGKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGG
ECCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCC
KSHFGGQRFGEMECWALQAYGATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPE
CCCCCCCCCCCCEEEEEEHHCHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEECCCH
SFNVMMNELRALCLNVEFCSDLEKKKDFGDLALAASGQ
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA