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The map label for this gene is rpoC

Identifier: 88608346

GI number: 88608346

Start: 594093

End: 598220

Strand: Reverse

Name: rpoC

Synonym: NSE_0677

Alternate gene names: 88608346

Gene position: 598220-594093 (Counterclockwise)

Preceding gene: 88608380

Following gene: 88608839

Centisome position: 69.64

GC content: 44.23

Gene sequence:

>4128_bases
ATGGGAGATTTTAGGAGTTTTCGCCAGAATGGGGGCAGCTCGGTTGATTTTGATGGTATCAAGATTTCCCTTGCGAGTGC
TGATAAGATACGGTCTCTTTCTTATGGGGAGGTCACTAAGCCCGAGACTATCAATTACAGGACATTCAAGCCAGAAAAAA
ATGGTCTTTTCTGCGCAAAAATTTTTGGTCCTACAAAGAGTTACGAGTGTCTTTGTGGGAAATATAAAAAGATTAAGTAC
AGTGGGGTAATTTGCGAGAGGTGTGGTGTAGAGGTTACTTCCTCAAGAGTACGCCGTGAGCGTATGGGGCATATAGAGCT
GGCTAGTCCTGTTGCACATATATGGTTTTTAAAATCTCTTCCATCGAAGATTTGCATTTTGCTGGACTTGACGCTTAAAA
ATGTGGAGAAAGTGCTCTACTTTGAGTTGTATATAGTAATCGATCCGGGTGTTACTACATTTACTAAAAACGAGCTCATC
ACTGATGAAGCCTATATGAATGCAGTTCGTGAATACGGTCCCGACTCGTTTACTGCGATGATAGGTGCCGAGGCTATTAG
ACATATGCTTGCTTCACTGGATCTGGAAAAGATGGCAGTGAAATTACGCTCTCAGGCAGCTGCAACGAATTCTGAAGTAA
AGAAAAAAAAGATCATTAAGACGCTCCGTCTAGTAGAACAATTTCTTGGATCAGACAGTAGGCCGGTTGATATGATTTTA
GATGTCATACCAGTAATGCCACCTGATCTTAGGCCGCTTGTTATGTTGGATGGTGGAAGGTTTGCGACCTCTGATTTGAA
TGCGTTGTACAGATCAGTGATCAACCGGAACAATAGATTGAAGAGTCTGATCTATCTGAAAGCGCCCAATATTATCATAA
ATAACGAAAGACGGATGTTACAGGAAGCTGTAGATGCACTTTTCGATAATGGGCGTCGTGCAAAAGTTATTAAGGGTAGT
AACAAGCGACCTTACAAATCCATTAGTGATATGCTTAAGGGGAAACAAGGTAGGTTCCGGCAGAATCTCCTTGGCAAACG
CGTAGACTATTCTGGGAGATCCGTGATAGTTGTTGGTCCGGCCCTAGAGCTTCATCAGTGTGGGCTGCCTAAAAAAATTG
CGCTGGAGTTGTTCAAACCTTTCATATATTCCAAACTGGAACTTTATGGAATTGCTCCGACGATCAAGACTGCTCGGAGG
ATGGTACAAAATGAACAGCCAGAAGTCTGGGATGTACTTGCTAAGGTTATTCATCAGCACCCTGTTTTCTTGAATAGAGC
ACCTACCCTTCATAGGCTGAGTGTCCAAGCGTTCGAGCCAGTTCTTATTGAAGGTAAAGCAATACAATTGCATCCGTTAG
TTTGCACTGCATTCAACGCTGATTTTGACGGTGATCAGATGTCTGTGCACGTTCCTTTGTCTATTGAGGCACAAGTTGAA
GCTAGGTTGCTTGTTATGTCGACGAATAATGTCCTCAATCCAGCCAATTCACGCCCGATTATTGTCCCATCTAAGGACAT
AGTTTTAGGCGTGTATTATCTTAGCCTCGAGGAGAAAGGGGGCGTTGTCCATCCGGTGACTTTTTGTGCTACATGGGAGG
CTGAGCATGCTTTCGCAAATGGTGATATTGGGCTTCATACTAAGATCAGATGCGGAATTGAGCTAGAAGATGGGGTAAAA
GTTTATACAACGACTTTTGGTAGATTACAGTTGCTCAAAATTCTTCCAAAGGGTGTGCCGTTTGAAAGTATAAACATGGT
GCTTACGGTTAGAGATATAAGCAATCTTGTTGATTTGGTATATAAGACTTGCGGTCATGGTAAAACTGTTGAGTTTGCAG
ATGGCATCATGGAATTGGGTTTTAGGTATGCGACGCTCTCGGGTATTTCCTTTGGGAAAGATGATATGGTTGTACCTCCA
ACAAAATCGGAGCATGTGAGAAGAGCAAACGAAGAGGTTAAGGAGTACGAATTTCAGTATCAAGAGGGTTTGATCACCAA
ACACGAAAAATACAATAAGGTTGTTGATGCGTGGCAGAAATGTACGGACCTTGTCGCAAAAGACATGATGGATGGAATTT
CTGGGTATGAAAGCGTTGCGGAGATGAATTCCATCTTTATGATGGCACAATCTGGTGCTAGGGGTTCCGCCGCGCAGATA
AAGCAGCTTGCTGGAATGCGGGGGCTGATGGCGAAGCCATCCGGTGAGATTATCCCGAATCCAATCATATCAAATTTAAG
GGAAGGACAGGGCGTTTTAGAGTACTTTAACTCTACGCATGGCGCACGTAAGGGACTTGCAGATACAGCATTAAAAACTG
CGAACTCTGGTTATCTGACTCGTAGGCTAGTTGATGTAGCACAGGATTCTATTATCGTTGAAGAGGATTGCGGCTCCTCC
AATGGGTTAGTGGTTCGCGCCACCGTTGAGGGTGGTGTGGTGATTATACCGCTCAGTGATAGTATATTTAGTAGAGTTTC
TGCGACTGATATTATAGACCCATCGGATGGTTCCGTGATAGTGCGTGCAGGAGAGATGTTCGATGATAAGTCCATTGAAA
GAATAGAGTCGCTTGGTATAGATTCGGTTCGGATTCGTTCGGTTCTCACATGCAAAAGTAAACACGGTATATGTCGCAAG
TGCTATGGTGCGGATCTTTCAAATAGGAAGTTGGTTGCCCTTGGTGAAGCAGTAGGTGTAATTGCTGCCCAGTCGGTGGG
TGAACCTGGCACACAGCTCACAATGAGGACATTCCACGTTGGTGGTGCAGCGACGCGCAGAGTGGAAAACTCGAGTATGG
TTGCGTTTTGTGGGGGTAAGGTTAAGTTTACGAACGCGAACTTGATTACGGACCGTGATGGCAACTATGTTGTCTTGAGT
AGGTCGTTTGAGATCTTGCTTGTTGATTCTCTTGGTATAGAGCACTTTCAAGGTAGGGTGCAGTATGGTGGGACCGTATA
TGTCAAAGAGGGTGAAGTTGTTCCAATTGGGAAGAAGTTAGCAGACTGGGATTTGTACACTGTACCTATAGTAGCAGAGG
CGTCTGGCACGGTATCTTATGCGGATATGATAGAAGGTGTCTCGTACAATGAGGTTCATGATGAAAGTACCGGCATTCTA
AATAGAATGGTTGTTGATTGGCGTCAAGCAGAGTCCTCTTCGGGGTTGCGTCCACGTGTTGAGATACTCGATGAGAGTGG
TTCAGTTGCAAAGTGTCAGTACTCTAAAGATGCGGTTTATCTACTGCCGCTTGGAGCGATACTCAATGTGTCGAACGGCG
ATGTTGTTAAAGCTGGGGATGTGATTGCGAAGATCACGAAAGAGTCAACAACTACCCGTGATATTACTGGTGGTCTGCCT
CGCGTGATCGAGCTGTTTGAAGCAAGGAAAGCTAAAGTTAACGCAGTGATTAGTGAAATTGATGGCTACGTTGAATTCGC
AAAGGATTACTATAAATCAAAAAGAAAAGTTATTGTCAGGTCGCGTGAAGATAAGGAACGGATTTATGAGTACCTTGTAC
CAAAAGGTAGACATTTGATTGTTAGTGAGGGGGATTTTATTAGAAGGGGTGAGCCCCTTATGGATGGTGATCCAGATTTG
CACGAGATTCTCAGGGTGCTTGGTTTGGAGGCCCTTGCGGAGTATATGATTAGCGAGATACAACGCGTCTACAGGTTGCA
GGGGGTTAAAATCAATAATAAACACATAGAAGTTATAATTCGTAAGATGCTGCAAAAAGTTGAGATCACTGATGCTGGTG
ATACAACTTTCCTTATTGGGGAGCAGATTGATAAGTCTCGTGTAGAGCGGATCAATGAGGTTATGGCGTCACAGGGGTTG
AGATGCTGTTCTTATGTACCGGTCCTGTTAGGTATTACAAGGGCAAGTTTGCAGACAGAGTCGTTTATTTCAGCAGCCTC
ATTCCAGGAAACTACTAAGGTGTTAACTGAGGCTGCGGTTGCCGGTAAGGTTGACAGACTAAGAGGTCTGAAAGAGAATA
TTATAGCAGGCAGGTTGTTACCTGTTGGCGCTGGGTATTTTATCGATAAATTAAAGCGCGAGTTTACTGGCGAACGGCAA
GGTAAACAAGTGTCTGTTGGCGTAGGTGGTGATTTGACCTCCACCTAG

Upstream 100 bases:

>100_bases
AAAGAAAGATTTTGGTGATCTTGCATTAGCAGCATCGGGACAATAGGTGGTTAAAAAGAATATTTGCTTTCGGTTTCTAT
AGGGGTGGTCCTTTTTGTTT

Downstream 100 bases:

>100_bases
TGAGCTGTTTATTGTTTTTCGAGGTGTAGTTGAATATGAGTAAAGGTGCTTTCCATGTTTTGAGTCCTAGTCCTTGGCCT
ATTTTTACAGCTGCTTCTTC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1375; Mature: 1374

Protein sequence:

>1375_residues
MGDFRSFRQNGGSSVDFDGIKISLASADKIRSLSYGEVTKPETINYRTFKPEKNGLFCAKIFGPTKSYECLCGKYKKIKY
SGVICERCGVEVTSSRVRRERMGHIELASPVAHIWFLKSLPSKICILLDLTLKNVEKVLYFELYIVIDPGVTTFTKNELI
TDEAYMNAVREYGPDSFTAMIGAEAIRHMLASLDLEKMAVKLRSQAAATNSEVKKKKIIKTLRLVEQFLGSDSRPVDMIL
DVIPVMPPDLRPLVMLDGGRFATSDLNALYRSVINRNNRLKSLIYLKAPNIIINNERRMLQEAVDALFDNGRRAKVIKGS
NKRPYKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPALELHQCGLPKKIALELFKPFIYSKLELYGIAPTIKTARR
MVQNEQPEVWDVLAKVIHQHPVFLNRAPTLHRLSVQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMSVHVPLSIEAQVE
ARLLVMSTNNVLNPANSRPIIVPSKDIVLGVYYLSLEEKGGVVHPVTFCATWEAEHAFANGDIGLHTKIRCGIELEDGVK
VYTTTFGRLQLLKILPKGVPFESINMVLTVRDISNLVDLVYKTCGHGKTVEFADGIMELGFRYATLSGISFGKDDMVVPP
TKSEHVRRANEEVKEYEFQYQEGLITKHEKYNKVVDAWQKCTDLVAKDMMDGISGYESVAEMNSIFMMAQSGARGSAAQI
KQLAGMRGLMAKPSGEIIPNPIISNLREGQGVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDSIIVEEDCGSS
NGLVVRATVEGGVVIIPLSDSIFSRVSATDIIDPSDGSVIVRAGEMFDDKSIERIESLGIDSVRIRSVLTCKSKHGICRK
CYGADLSNRKLVALGEAVGVIAAQSVGEPGTQLTMRTFHVGGAATRRVENSSMVAFCGGKVKFTNANLITDRDGNYVVLS
RSFEILLVDSLGIEHFQGRVQYGGTVYVKEGEVVPIGKKLADWDLYTVPIVAEASGTVSYADMIEGVSYNEVHDESTGIL
NRMVVDWRQAESSSGLRPRVEILDESGSVAKCQYSKDAVYLLPLGAILNVSNGDVVKAGDVIAKITKESTTTRDITGGLP
RVIELFEARKAKVNAVISEIDGYVEFAKDYYKSKRKVIVRSREDKERIYEYLVPKGRHLIVSEGDFIRRGEPLMDGDPDL
HEILRVLGLEALAEYMISEIQRVYRLQGVKINNKHIEVIIRKMLQKVEITDAGDTTFLIGEQIDKSRVERINEVMASQGL
RCCSYVPVLLGITRASLQTESFISAASFQETTKVLTEAAVAGKVDRLRGLKENIIAGRLLPVGAGYFIDKLKREFTGERQ
GKQVSVGVGGDLTST

Sequences:

>Translated_1375_residues
MGDFRSFRQNGGSSVDFDGIKISLASADKIRSLSYGEVTKPETINYRTFKPEKNGLFCAKIFGPTKSYECLCGKYKKIKY
SGVICERCGVEVTSSRVRRERMGHIELASPVAHIWFLKSLPSKICILLDLTLKNVEKVLYFELYIVIDPGVTTFTKNELI
TDEAYMNAVREYGPDSFTAMIGAEAIRHMLASLDLEKMAVKLRSQAAATNSEVKKKKIIKTLRLVEQFLGSDSRPVDMIL
DVIPVMPPDLRPLVMLDGGRFATSDLNALYRSVINRNNRLKSLIYLKAPNIIINNERRMLQEAVDALFDNGRRAKVIKGS
NKRPYKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPALELHQCGLPKKIALELFKPFIYSKLELYGIAPTIKTARR
MVQNEQPEVWDVLAKVIHQHPVFLNRAPTLHRLSVQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMSVHVPLSIEAQVE
ARLLVMSTNNVLNPANSRPIIVPSKDIVLGVYYLSLEEKGGVVHPVTFCATWEAEHAFANGDIGLHTKIRCGIELEDGVK
VYTTTFGRLQLLKILPKGVPFESINMVLTVRDISNLVDLVYKTCGHGKTVEFADGIMELGFRYATLSGISFGKDDMVVPP
TKSEHVRRANEEVKEYEFQYQEGLITKHEKYNKVVDAWQKCTDLVAKDMMDGISGYESVAEMNSIFMMAQSGARGSAAQI
KQLAGMRGLMAKPSGEIIPNPIISNLREGQGVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDSIIVEEDCGSS
NGLVVRATVEGGVVIIPLSDSIFSRVSATDIIDPSDGSVIVRAGEMFDDKSIERIESLGIDSVRIRSVLTCKSKHGICRK
CYGADLSNRKLVALGEAVGVIAAQSVGEPGTQLTMRTFHVGGAATRRVENSSMVAFCGGKVKFTNANLITDRDGNYVVLS
RSFEILLVDSLGIEHFQGRVQYGGTVYVKEGEVVPIGKKLADWDLYTVPIVAEASGTVSYADMIEGVSYNEVHDESTGIL
NRMVVDWRQAESSSGLRPRVEILDESGSVAKCQYSKDAVYLLPLGAILNVSNGDVVKAGDVIAKITKESTTTRDITGGLP
RVIELFEARKAKVNAVISEIDGYVEFAKDYYKSKRKVIVRSREDKERIYEYLVPKGRHLIVSEGDFIRRGEPLMDGDPDL
HEILRVLGLEALAEYMISEIQRVYRLQGVKINNKHIEVIIRKMLQKVEITDAGDTTFLIGEQIDKSRVERINEVMASQGL
RCCSYVPVLLGITRASLQTESFISAASFQETTKVLTEAAVAGKVDRLRGLKENIIAGRLLPVGAGYFIDKLKREFTGERQ
GKQVSVGVGGDLTST
>Mature_1374_residues
GDFRSFRQNGGSSVDFDGIKISLASADKIRSLSYGEVTKPETINYRTFKPEKNGLFCAKIFGPTKSYECLCGKYKKIKYS
GVICERCGVEVTSSRVRRERMGHIELASPVAHIWFLKSLPSKICILLDLTLKNVEKVLYFELYIVIDPGVTTFTKNELIT
DEAYMNAVREYGPDSFTAMIGAEAIRHMLASLDLEKMAVKLRSQAAATNSEVKKKKIIKTLRLVEQFLGSDSRPVDMILD
VIPVMPPDLRPLVMLDGGRFATSDLNALYRSVINRNNRLKSLIYLKAPNIIINNERRMLQEAVDALFDNGRRAKVIKGSN
KRPYKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPALELHQCGLPKKIALELFKPFIYSKLELYGIAPTIKTARRM
VQNEQPEVWDVLAKVIHQHPVFLNRAPTLHRLSVQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMSVHVPLSIEAQVEA
RLLVMSTNNVLNPANSRPIIVPSKDIVLGVYYLSLEEKGGVVHPVTFCATWEAEHAFANGDIGLHTKIRCGIELEDGVKV
YTTTFGRLQLLKILPKGVPFESINMVLTVRDISNLVDLVYKTCGHGKTVEFADGIMELGFRYATLSGISFGKDDMVVPPT
KSEHVRRANEEVKEYEFQYQEGLITKHEKYNKVVDAWQKCTDLVAKDMMDGISGYESVAEMNSIFMMAQSGARGSAAQIK
QLAGMRGLMAKPSGEIIPNPIISNLREGQGVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDSIIVEEDCGSSN
GLVVRATVEGGVVIIPLSDSIFSRVSATDIIDPSDGSVIVRAGEMFDDKSIERIESLGIDSVRIRSVLTCKSKHGICRKC
YGADLSNRKLVALGEAVGVIAAQSVGEPGTQLTMRTFHVGGAATRRVENSSMVAFCGGKVKFTNANLITDRDGNYVVLSR
SFEILLVDSLGIEHFQGRVQYGGTVYVKEGEVVPIGKKLADWDLYTVPIVAEASGTVSYADMIEGVSYNEVHDESTGILN
RMVVDWRQAESSSGLRPRVEILDESGSVAKCQYSKDAVYLLPLGAILNVSNGDVVKAGDVIAKITKESTTTRDITGGLPR
VIELFEARKAKVNAVISEIDGYVEFAKDYYKSKRKVIVRSREDKERIYEYLVPKGRHLIVSEGDFIRRGEPLMDGDPDLH
EILRVLGLEALAEYMISEIQRVYRLQGVKINNKHIEVIIRKMLQKVEITDAGDTTFLIGEQIDKSRVERINEVMASQGLR
CCSYVPVLLGITRASLQTESFISAASFQETTKVLTEAAVAGKVDRLRGLKENIIAGRLLPVGAGYFIDKLKREFTGERQG
KQVSVGVGGDLTST

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=838, Percent_Identity=24.9403341288783, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI39725938, Length=651, Percent_Identity=24.5775729646697, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI103471997, Length=770, Percent_Identity=23.8961038961039, Blast_Score=117, Evalue=8e-26,
Organism=Escherichia coli, GI2367335, Length=1382, Percent_Identity=54.4138929088278, Blast_Score=1494, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=897, Percent_Identity=24.4147157190635, Blast_Score=166, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25145495, Length=320, Percent_Identity=30.9375, Blast_Score=137, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=883, Percent_Identity=23.7825594563986, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=349, Percent_Identity=30.3724928366762, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281360912, Length=838, Percent_Identity=26.3723150357995, Blast_Score=187, Evalue=4e-47,
Organism=Drosophila melanogaster, GI17530899, Length=827, Percent_Identity=23.9419588875453, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI17647875, Length=324, Percent_Identity=25.9259259259259, Blast_Score=106, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_NEOSM (Q2GD91)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506555.1
- ProteinModelPortal:   Q2GD91
- SMR:   Q2GD91
- STRING:   Q2GD91
- GeneID:   3931848
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0677
- TIGR:   NSE_0677
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   IQAFHPV
- PhylomeDB:   Q2GD91
- BioCyc:   NSEN222891:NSE_0677-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 152092; Mature: 151961

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDFRSFRQNGGSSVDFDGIKISLASADKIRSLSYGEVTKPETINYRTFKPEKNGLFCAK
CCCHHHHHHCCCCEEECCCEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEE
IFGPTKSYECLCGKYKKIKYSGVICERCGVEVTSSRVRRERMGHIELASPVAHIWFLKSL
ECCCCCCCHHHHCCCCEEEECCEEHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHC
PSKICILLDLTLKNVEKVLYFELYIVIDPGVTTFTKNELITDEAYMNAVREYGPDSFTAM
CCCEEEEEEEHHHHHHHEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHH
IGAEAIRHMLASLDLEKMAVKLRSQAAATNSEVKKKKIIKTLRLVEQFLGSDSRPVDMIL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DVIPVMPPDLRPLVMLDGGRFATSDLNALYRSVINRNNRLKSLIYLKAPNIIINNERRML
HHHCCCCCCCCEEEEECCCEECHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCHHHHH
QEAVDALFDNGRRAKVIKGSNKRPYKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
ALELHQCGLPKKIALELFKPFIYSKLELYGIAPTIKTARRMVQNEQPEVWDVLAKVIHQH
CHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHC
PVFLNRAPTLHRLSVQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMSVHVPLSIEAQVE
CCEECCCCCCEEEEHHHCCCEEEECCEEEEEEEEEEEECCCCCCCEEEEEEEEEEEEEEE
ARLLVMSTNNVLNPANSRPIIVPSKDIVLGVYYLSLEEKGGVVHPVTFCATWEAEHAFAN
EEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCEECEEEEEEEECCCCCCCC
GDIGLHTKIRCGIELEDGVKVYTTTFGRLQLLKILPKGVPFESINMVLTVRDISNLVDLV
CCCCEEEEEEEEEEECCCCEEEEECHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHH
YKTCGHGKTVEFADGIMELGFRYATLSGISFGKDDMVVPPTKSEHVRRANEEVKEYEFQY
HHHCCCCCEEHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
QEGLITKHEKYNKVVDAWQKCTDLVAKDMMDGISGYESVAEMNSIFMMAQSGARGSAAQI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
KQLAGMRGLMAKPSGEIIPNPIISNLREGQGVLEYFNSTHGARKGLADTALKTANSGYLT
HHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCHHHCCHHHHHHHCCCCCHHH
RRLVDVAQDSIIVEEDCGSSNGLVVRATVEGGVVIIPLSDSIFSRVSATDIIDPSDGSVI
HHHHHHHHCCEEEECCCCCCCCEEEEEEECCCEEEEECCHHHHHHCCCCCCCCCCCCCEE
VRAGEMFDDKSIERIESLGIDSVRIRSVLTCKSKHGICRKCYGADLSNRKLVALGEAVGV
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECHHHHH
IAAQSVGEPGTQLTMRTFHVGGAATRRVENSSMVAFCGGKVKFTNANLITDRDGNYVVLS
HHHHCCCCCCCEEEEEEEECCCHHHEEECCCCEEEEECCEEEEECCEEEEECCCCEEEEE
RSFEILLVDSLGIEHFQGRVQYGGTVYVKEGEVVPIGKKLADWDLYTVPIVAEASGTVSY
CCEEEEEEECCCHHHHCCEEEECCEEEEECCCEEECCCCCCCCCEEEEEEEEECCCCEEH
ADMIEGVSYNEVHDESTGILNRMVVDWRQAESSSGLRPRVEILDESGSVAKCQYSKDAVY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCEEE
LLPLGAILNVSNGDVVKAGDVIAKITKESTTTRDITGGLPRVIELFEARKAKVNAVISEI
EEEECCEEECCCCCEEECCHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
DGYVEFAKDYYKSKRKVIVRSREDKERIYEYLVPKGRHLIVSEGDFIRRGEPLMDGDPDL
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCCH
HEILRVLGLEALAEYMISEIQRVYRLQGVKINNKHIEVIIRKMLQKVEITDAGDTTFLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHEECCCCCCEEEEEC
EQIDKSRVERINEVMASQGLRCCSYVPVLLGITRASLQTESFISAASFQETTKVLTEAAV
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKVDRLRGLKENIIAGRLLPVGAGYFIDKLKREFTGERQGKQVSVGVGGDLTST
HCCHHHHHCHHHHHHHCCEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
GDFRSFRQNGGSSVDFDGIKISLASADKIRSLSYGEVTKPETINYRTFKPEKNGLFCAK
CCHHHHHHCCCCEEECCCEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEE
IFGPTKSYECLCGKYKKIKYSGVICERCGVEVTSSRVRRERMGHIELASPVAHIWFLKSL
ECCCCCCCHHHHCCCCEEEECCEEHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHC
PSKICILLDLTLKNVEKVLYFELYIVIDPGVTTFTKNELITDEAYMNAVREYGPDSFTAM
CCCEEEEEEEHHHHHHHEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHH
IGAEAIRHMLASLDLEKMAVKLRSQAAATNSEVKKKKIIKTLRLVEQFLGSDSRPVDMIL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DVIPVMPPDLRPLVMLDGGRFATSDLNALYRSVINRNNRLKSLIYLKAPNIIINNERRML
HHHCCCCCCCCEEEEECCCEECHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCHHHHH
QEAVDALFDNGRRAKVIKGSNKRPYKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
ALELHQCGLPKKIALELFKPFIYSKLELYGIAPTIKTARRMVQNEQPEVWDVLAKVIHQH
CHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHC
PVFLNRAPTLHRLSVQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMSVHVPLSIEAQVE
CCEECCCCCCEEEEHHHCCCEEEECCEEEEEEEEEEEECCCCCCCEEEEEEEEEEEEEEE
ARLLVMSTNNVLNPANSRPIIVPSKDIVLGVYYLSLEEKGGVVHPVTFCATWEAEHAFAN
EEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCEECEEEEEEEECCCCCCCC
GDIGLHTKIRCGIELEDGVKVYTTTFGRLQLLKILPKGVPFESINMVLTVRDISNLVDLV
CCCCEEEEEEEEEEECCCCEEEEECHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHH
YKTCGHGKTVEFADGIMELGFRYATLSGISFGKDDMVVPPTKSEHVRRANEEVKEYEFQY
HHHCCCCCEEHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
QEGLITKHEKYNKVVDAWQKCTDLVAKDMMDGISGYESVAEMNSIFMMAQSGARGSAAQI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
KQLAGMRGLMAKPSGEIIPNPIISNLREGQGVLEYFNSTHGARKGLADTALKTANSGYLT
HHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCHHHCCHHHHHHHCCCCCHHH
RRLVDVAQDSIIVEEDCGSSNGLVVRATVEGGVVIIPLSDSIFSRVSATDIIDPSDGSVI
HHHHHHHHCCEEEECCCCCCCCEEEEEEECCCEEEEECCHHHHHHCCCCCCCCCCCCCEE
VRAGEMFDDKSIERIESLGIDSVRIRSVLTCKSKHGICRKCYGADLSNRKLVALGEAVGV
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECHHHHH
IAAQSVGEPGTQLTMRTFHVGGAATRRVENSSMVAFCGGKVKFTNANLITDRDGNYVVLS
HHHHCCCCCCCEEEEEEEECCCHHHEEECCCCEEEEECCEEEEECCEEEEECCCCEEEEE
RSFEILLVDSLGIEHFQGRVQYGGTVYVKEGEVVPIGKKLADWDLYTVPIVAEASGTVSY
CCEEEEEEECCCHHHHCCEEEECCEEEEECCCEEECCCCCCCCCEEEEEEEEECCCCEEH
ADMIEGVSYNEVHDESTGILNRMVVDWRQAESSSGLRPRVEILDESGSVAKCQYSKDAVY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCEEE
LLPLGAILNVSNGDVVKAGDVIAKITKESTTTRDITGGLPRVIELFEARKAKVNAVISEI
EEEECCEEECCCCCEEECCHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHH
DGYVEFAKDYYKSKRKVIVRSREDKERIYEYLVPKGRHLIVSEGDFIRRGEPLMDGDPDL
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCCH
HEILRVLGLEALAEYMISEIQRVYRLQGVKINNKHIEVIIRKMLQKVEITDAGDTTFLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHEECCCCCCEEEEEC
EQIDKSRVERINEVMASQGLRCCSYVPVLLGITRASLQTESFISAASFQETTKVLTEAAV
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKVDRLRGLKENIIAGRLLPVGAGYFIDKLKREFTGERQGKQVSVGVGGDLTST
HCCHHHHHCHHHHHHHCCEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA