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The map label for this gene is nuoA

Identifier: 88608319

GI number: 88608319

Start: 352330

End: 352785

Strand: Direct

Name: nuoA

Synonym: NSE_0429

Alternate gene names: 88608319

Gene position: 352330-352785 (Clockwise)

Preceding gene: 88608795

Following gene: 88608004

Centisome position: 41.02

GC content: 41.45

Gene sequence:

>456_bases
ATGACACATTGCCATAGCGACAGTATAAAATCGTTACCTAGCTCTATTTATGTGCTCATAAAGATGTTAGAATCCTCAGT
TGTTGGCATAGGAAAGTGGGTAGTGGAGGACTATATTTTCGTTGGTCTCTTCTTTGTTGTGGCGTGCTTCATTAGCTGCG
TAATGCTTGCCTTGCCGGTTTTTATTGCGCCTTCTTCACATGAGAGGCACAAGGGTGATAGCTACGAGTGCGGCTTTGAC
AAATTAAGCTCTACTGGTGAAAGATTTAATGTCCGGTTTTATTTGGTGGGAATACTGTTTATCATCTTCGATCTGGAGAT
AATTTTCCTTTTCCCCTGGGCTGTAAGTGCTAGGGAACTTGGTCCTGCAGCTTTCGTTTCGGTATTAATCTTTCTCATTA
TTTTGACTGTCGGATTTGTGTATGAATTTGTTTCTGGTGCACTAGATTGGAGGTAA

Upstream 100 bases:

>100_bases
CTCAAGAAGCGAGAAGTATAAAAAAGATGATAGCGATCGTATACCTATTCTTCTACTAAAGCAAGAGGGCTAAATCTTAG
TTACAGCGAGCTAAGAACTA

Downstream 100 bases:

>100_bases
ATGACCTGGTTGGGAGATTGGTTGTATCGGTAAAATCTATCTTTAGGCGCAGAGATGTGTTCGACCTGGTATCAGTTATT
GTTTTAGCTTCTTGCATTGG

Product: NADH dehydrogenase I subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTHCHSDSIKSLPSSIYVLIKMLESSVVGIGKWVVEDYIFVGLFFVVACFISCVMLALPVFIAPSSHERHKGDSYECGFD
KLSSTGERFNVRFYLVGILFIIFDLEIIFLFPWAVSARELGPAAFVSVLIFLIILTVGFVYEFVSGALDWR

Sequences:

>Translated_151_residues
MTHCHSDSIKSLPSSIYVLIKMLESSVVGIGKWVVEDYIFVGLFFVVACFISCVMLALPVFIAPSSHERHKGDSYECGFD
KLSSTGERFNVRFYLVGILFIIFDLEIIFLFPWAVSARELGPAAFVSVLIFLIILTVGFVYEFVSGALDWR
>Mature_150_residues
THCHSDSIKSLPSSIYVLIKMLESSVVGIGKWVVEDYIFVGLFFVVACFISCVMLALPVFIAPSSHERHKGDSYECGFDK
LSSTGERFNVRFYLVGILFIIFDLEIIFLFPWAVSARELGPAAFVSVLIFLIILTVGFVYEFVSGALDWR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=109, Percent_Identity=39.4495412844037, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16975; Mature: 16844

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHCHSDSIKSLPSSIYVLIKMLESSVVGIGKWVVEDYIFVGLFFVVACFISCVMLALPV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIAPSSHERHKGDSYECGFDKLSSTGERFNVRFYLVGILFIIFDLEIIFLFPWAVSAREL
HCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPAAFVSVLIFLIILTVGFVYEFVSGALDWR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
THCHSDSIKSLPSSIYVLIKMLESSVVGIGKWVVEDYIFVGLFFVVACFISCVMLALPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIAPSSHERHKGDSYECGFDKLSSTGERFNVRFYLVGILFIIFDLEIIFLFPWAVSAREL
HCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPAAFVSVLIFLIILTVGFVYEFVSGALDWR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA