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The map label for this gene is lysK

Identifier: 88608230

GI number: 88608230

Start: 688535

End: 690052

Strand: Reverse

Name: lysK

Synonym: NSE_0773

Alternate gene names: 88608230

Gene position: 690052-688535 (Counterclockwise)

Preceding gene: 88608501

Following gene: 88608229

Centisome position: 80.33

GC content: 41.63

Gene sequence:

>1518_bases
ATGGAAACACAAACTGCCTGGCCAATAGAAGAGGCAAAGAAACTACTACCTAGGATAAAAGATGGCAAGATAATACTTTT
TGAAACTGGATATGGTCCTTCAGGTTTACCTCATATAGGAACATTCGGAGAAGTGGTGCGAACCATAATGGTTATGAAAG
CACTGCAATATCTTTCTCCTGATGTAAAAATGAAACTTATCTGTTTCTCTGATGATATGGATGGACTAAGAAAGGTGCCT
GACAATGTCCCCAACCCCGACGAAGTAAGGAAATACCTTGGATACGCACTGACTTCAATTCCAGATCCCTTTGGTACGCA
TGAGAGTTATGGTGCGCATATGAATGCAAGGCTGATGTCCTTTTTGGATCTTTTCGGTTTTGAATATGAGTTTAAAAGTT
CCACTGAGTGCTATAAATCTGGTCTGTTCAATGAACAATTACTCCTTGCATTAAAGCATAACCAAGAGCTTCTGAACTTA
ATAAAGCCAACACTTGGTGATGAACGACAACAGACATATAGTCCATTTCTTCCGGTCAGGGATGGTAAAGTGCTTCAAGC
GGAAGTTGTCGAACTTAAAGAAGATAGCATTGTGTACAAAGATCCGGAGTGCGGAAAATTGTTTGAATCTCCTGTAACTG
GAGGTAACTGCAAGTTGCAGTGGAAGGTGGACTGGGGGATGCGTTGGGCAGCACTTGGCGTGGATTTTGAATTTCATGGA
AAAGACTTAACTCCTTCTGCGGTTTTGTCCGCAAGAGTTGCGCGCATACTAGGTGCTGAACCCCCAGAACTTTCTGTTTA
TGAACTCTTTCTCGATGAAGAAGGCAAAAAAATCTCGAAGTCCAAAGGTAATGGTTTGACGATAGAGGAATGGCTTAAAT
ACGCTCCTTGGGAGAGTTTAGCGTTTTTTATGTTTCAGAATCCCAAGAGGGCGAAGCGTCTGTATTTCGATGTTATTCCA
CGAAGTGTTGACGATTACTTGCGTTTTTCTGAGTCTTTCGAGGAGGGTGATCTGACAAATCCTCTTAGCTTCATTGATGC
AAAGGACCGAAACATAACAAAGGGAATTAGCTATTCGTTGCTTTTGAATCTTGCTTCTGCATGTAATCCTGAGAATTCCA
GTGTACTTTGGGGTTTTATACAACGTTACAGTCCAGCTGCGACGCCTGAAAATGATTCTTTACTGGGAAGGTTGGTCGAT
CATGCAATTGCATATTATAGAGACTTCGTAGGTTCAAATAAGATTTACAGAGTAGCAACTGACAGTGAGGCAAAGGCATT
GCTTGCCCTATCTCGGGAACTAAGTAAAATTCCTTCCGATGCTACAGCGGATGACATACAACGTGTTGTATACCTTGTTG
GCAAGGAAGAAGGGTATTCTTCAGACATAAAAGGATGGTTTCAGGTGCTGTATCAGATATTGCTTGGTCAGAACGAGGGA
CCAAGAATAGGATCATTTTTTGCGCTATATGGCTTAAATAACGCCATCGCCATGATAAAAAGTGTAGCTACAAGATAA

Upstream 100 bases:

>100_bases
AAAATTCCAACTAATTTGGAAGAGTGTTCTCACTAGATGCGGCTACCGTTTTTTGTGCTAACATTAATGCTTCAGTCCGG
AAGCTCCTTACCAATTGGAA

Downstream 100 bases:

>100_bases
AGCTCCGTTAGGTGAGTACTTTTAGCTACTCTAATGTTATACTCCTGGTGATTTAGGGTTGCTGTGGCGCTTTTAGAAGC
CTGACTATTTCGAATGTGTG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
METQTAWPIEEAKKLLPRIKDGKIILFETGYGPSGLPHIGTFGEVVRTIMVMKALQYLSPDVKMKLICFSDDMDGLRKVP
DNVPNPDEVRKYLGYALTSIPDPFGTHESYGAHMNARLMSFLDLFGFEYEFKSSTECYKSGLFNEQLLLALKHNQELLNL
IKPTLGDERQQTYSPFLPVRDGKVLQAEVVELKEDSIVYKDPECGKLFESPVTGGNCKLQWKVDWGMRWAALGVDFEFHG
KDLTPSAVLSARVARILGAEPPELSVYELFLDEEGKKISKSKGNGLTIEEWLKYAPWESLAFFMFQNPKRAKRLYFDVIP
RSVDDYLRFSESFEEGDLTNPLSFIDAKDRNITKGISYSLLLNLASACNPENSSVLWGFIQRYSPAATPENDSLLGRLVD
HAIAYYRDFVGSNKIYRVATDSEAKALLALSRELSKIPSDATADDIQRVVYLVGKEEGYSSDIKGWFQVLYQILLGQNEG
PRIGSFFALYGLNNAIAMIKSVATR

Sequences:

>Translated_505_residues
METQTAWPIEEAKKLLPRIKDGKIILFETGYGPSGLPHIGTFGEVVRTIMVMKALQYLSPDVKMKLICFSDDMDGLRKVP
DNVPNPDEVRKYLGYALTSIPDPFGTHESYGAHMNARLMSFLDLFGFEYEFKSSTECYKSGLFNEQLLLALKHNQELLNL
IKPTLGDERQQTYSPFLPVRDGKVLQAEVVELKEDSIVYKDPECGKLFESPVTGGNCKLQWKVDWGMRWAALGVDFEFHG
KDLTPSAVLSARVARILGAEPPELSVYELFLDEEGKKISKSKGNGLTIEEWLKYAPWESLAFFMFQNPKRAKRLYFDVIP
RSVDDYLRFSESFEEGDLTNPLSFIDAKDRNITKGISYSLLLNLASACNPENSSVLWGFIQRYSPAATPENDSLLGRLVD
HAIAYYRDFVGSNKIYRVATDSEAKALLALSRELSKIPSDATADDIQRVVYLVGKEEGYSSDIKGWFQVLYQILLGQNEG
PRIGSFFALYGLNNAIAMIKSVATR
>Mature_505_residues
METQTAWPIEEAKKLLPRIKDGKIILFETGYGPSGLPHIGTFGEVVRTIMVMKALQYLSPDVKMKLICFSDDMDGLRKVP
DNVPNPDEVRKYLGYALTSIPDPFGTHESYGAHMNARLMSFLDLFGFEYEFKSSTECYKSGLFNEQLLLALKHNQELLNL
IKPTLGDERQQTYSPFLPVRDGKVLQAEVVELKEDSIVYKDPECGKLFESPVTGGNCKLQWKVDWGMRWAALGVDFEFHG
KDLTPSAVLSARVARILGAEPPELSVYELFLDEEGKKISKSKGNGLTIEEWLKYAPWESLAFFMFQNPKRAKRLYFDVIP
RSVDDYLRFSESFEEGDLTNPLSFIDAKDRNITKGISYSLLLNLASACNPENSSVLWGFIQRYSPAATPENDSLLGRLVD
HAIAYYRDFVGSNKIYRVATDSEAKALLALSRELSKIPSDATADDIQRVVYLVGKEEGYSSDIKGWFQVLYQILLGQNEG
PRIGSFFALYGLNNAIAMIKSVATR

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 56890; Mature: 56890

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQTAWPIEEAKKLLPRIKDGKIILFETGYGPSGLPHIGTFGEVVRTIMVMKALQYLSP
CCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
DVKMKLICFSDDMDGLRKVPDNVPNPDEVRKYLGYALTSIPDPFGTHESYGAHMNARLMS
CCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
FLDLFGFEYEFKSSTECYKSGLFNEQLLLALKHNQELLNLIKPTLGDERQQTYSPFLPVR
HHHHHCCCEECCCCHHHHHCCCCCHHHHEEECCCHHHHHHHCCCCCCCHHHHCCCCCCCC
DGKVLQAEVVELKEDSIVYKDPECGKLFESPVTGGNCKLQWKVDWGMRWAALGVDFEFHG
CCCCHHHHHHHHCCCCEEECCCCHHHHHCCCCCCCCEEEEEEECCCCEEEEEECEEEECC
KDLTPSAVLSARVARILGAEPPELSVYELFLDEEGKKISKSKGNGLTIEEWLKYAPWESL
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHCCCCCCCCHHHHHHHCCHHHH
AFFMFQNPKRAKRLYFDVIPRSVDDYLRFSESFEEGDLTNPLSFIDAKDRNITKGISYSL
EEHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHCCHHHH
LLNLASACNPENSSVLWGFIQRYSPAATPENDSLLGRLVDHAIAYYRDFVGSNKIYRVAT
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DSEAKALLALSRELSKIPSDATADDIQRVVYLVGKEEGYSSDIKGWFQVLYQILLGQNEG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
PRIGSFFALYGLNNAIAMIKSVATR
CCHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
METQTAWPIEEAKKLLPRIKDGKIILFETGYGPSGLPHIGTFGEVVRTIMVMKALQYLSP
CCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
DVKMKLICFSDDMDGLRKVPDNVPNPDEVRKYLGYALTSIPDPFGTHESYGAHMNARLMS
CCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
FLDLFGFEYEFKSSTECYKSGLFNEQLLLALKHNQELLNLIKPTLGDERQQTYSPFLPVR
HHHHHCCCEECCCCHHHHHCCCCCHHHHEEECCCHHHHHHHCCCCCCCHHHHCCCCCCCC
DGKVLQAEVVELKEDSIVYKDPECGKLFESPVTGGNCKLQWKVDWGMRWAALGVDFEFHG
CCCCHHHHHHHHCCCCEEECCCCHHHHHCCCCCCCCEEEEEEECCCCEEEEEECEEEECC
KDLTPSAVLSARVARILGAEPPELSVYELFLDEEGKKISKSKGNGLTIEEWLKYAPWESL
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHCCCCCCCCHHHHHHHCCHHHH
AFFMFQNPKRAKRLYFDVIPRSVDDYLRFSESFEEGDLTNPLSFIDAKDRNITKGISYSL
EEHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHCCHHHH
LLNLASACNPENSSVLWGFIQRYSPAATPENDSLLGRLVDHAIAYYRDFVGSNKIYRVAT
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DSEAKALLALSRELSKIPSDATADDIQRVVYLVGKEEGYSSDIKGWFQVLYQILLGQNEG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
PRIGSFFALYGLNNAIAMIKSVATR
CCHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA