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The map label for this gene is argS

Identifier: 88608193

GI number: 88608193

Start: 38541

End: 40253

Strand: Direct

Name: argS

Synonym: NSE_0049

Alternate gene names: 88608193

Gene position: 38541-40253 (Clockwise)

Preceding gene: 88608060

Following gene: 88608576

Centisome position: 4.49

GC content: 41.1

Gene sequence:

>1713_bases
ATGGACTTGTTCTTGAGGTTAGGTAATGTACTGACTGAAGTGGTTACCTCGATTTTCGGTGTGACACTTAGTGAACAAGT
TTTGCTCTGGAACTCTCCAAAAAAAAGAGAGTATGGAGACTTTTCCACGGCCATTTCTTTTCTCATTGCCAAAGAGGTTA
GGCTTTCCTTACATGAGGTAGCTTGTTCTATAGCGGATGGTTTAAGATCTTTTAAGGACCTTTTCAAGAATGTCTCTGTA
GCCTCTGGGGGTTTTATTAACGTTTTTCTTACAAGTGACACATGGTCCGAATTTTTGGCTGCGGTGAGTGATGATGCTGG
TGGTTATGGATTTTCGGATATTGGCCATGCTGTTCCTTTGAACCTAGAGTTTGTGTCAGCGAATCCTACTGGTCCGCTTC
ACTTAGGACATATTAGAGGCGCGGTTCTCTTTGATATCTTTGCAGAGCTGTTGGACAAGTTCGGGTTTTCCCTTACGCGG
GAGTACTACATTAATGACGCCGGAAAACAAATTGATTTACTAGTCTATTCCGTCTTCGTACGGTTTTGCGAGCAGCTGCG
GAAAAAAGAGAGCGATAATTTTCCGAGTAATTGCTATGCCGGCGACTATATAAGGGATATAGCAAGTTATCTTATTTCCA
CGTTTCCTGATTCCGTTAAAGATACTACAGAGTTGAAAAGCTTCTCAGACACTTTCCGGGAAGTGATACTTTCACTAACC
ATGGACATGATAAAGTCCGATTTAGCTAAGTTGGGCATAAGTTACGATTGTTATGTCAGGGAAAAAGAGCTGCATGAGGG
AAATTATATTGAAAAGGTAATAGCAGTCCTTGACGAAAAAGGTTATTTAGATGAGGAAGAATTGCCGTCGCCTAAGGGGA
AGAGTGGGGATTGGGTAGAAAGAAGACAAAAGGTCTTCCTTTCGACGAAGTTTGGTGATGACACGAATAGAGCGCTACAA
AAAGTAGATGGGAGTTGGACTTATTTCGCATCGGATGTTGCATATCACTATCATAAACTTGAACGTGGTTTCAATCATAT
GATTGTTGGTTTAGGTGCTGATCACGCTGGGTATGTTAAGAGGCTTTCTGGTGTAGTCGAGGCACTCTCTGGAGGTGATG
CACGCATCGATATCAAATTGTATAATCTTGTTAACCTTTTCAGAAATGGAAAGCCAGTAAAACTTTCTAAACGCAATGGT
GACCTTATAACGCTCGATGATGTCCTAGAGAGTGGTATTACGGTAAGTGAAATACGATTCGCCATGCTGACTAAAAGTAG
CGAAATCGTGTTGGATTTTGATTTAGATAAATTCGTTCGTGCCTCGTACGATAACCCGCTTTTTTATGTCCAGTACGCGC
ATGCACGTTGCTCTTCCTTACTTAGAAAACGTGGACCTTCAGCTAAGTGTGATGCTGCAATGCTTGTGGAAAAACAGGAG
CTTGATTTGATGGTTACTCTTGCAAAGTTACCTTCTCTTCTTAAAGTGATTGTAGTTTCAGGTGAAGTGCATAAGTTGAC
TTTTTATTTACATGAAGTTGCAGAAAGGTTTCATGCTTTGTGGAACGCAGGTATGATAGAAAACAAGTTCAGATTCATTA
TAGAAGATGAACCAGAGCTCACGAACGCAAGGTTGATATTGGTGAAAGCTGTGAAGAACACACTAGCTTCTGTTCTCAAA
GTGATGAAAATTGAACCTGCAGAAAGAATGTAA

Upstream 100 bases:

>100_bases
TCTATTCTACGGAAGGTCCTTGTTTCTTTGAACATTATCTTTGTTGGCTCTACTCTTTTTGCGTTTGTAGCTGTATTTTA
TAGATTATTTTTTTAGCCTT

Downstream 100 bases:

>100_bases
AGACACCCAGACGACGAGGCCTCACAGCCTAGCAAGGCCATTAAAACAAAAAAGAACGACCTGAATGCCTTGCAAGAGAA
CTCAGCTAAGACTCTCGCAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDLFLRLGNVLTEVVTSIFGVTLSEQVLLWNSPKKREYGDFSTAISFLIAKEVRLSLHEVACSIADGLRSFKDLFKNVSV
ASGGFINVFLTSDTWSEFLAAVSDDAGGYGFSDIGHAVPLNLEFVSANPTGPLHLGHIRGAVLFDIFAELLDKFGFSLTR
EYYINDAGKQIDLLVYSVFVRFCEQLRKKESDNFPSNCYAGDYIRDIASYLISTFPDSVKDTTELKSFSDTFREVILSLT
MDMIKSDLAKLGISYDCYVREKELHEGNYIEKVIAVLDEKGYLDEEELPSPKGKSGDWVERRQKVFLSTKFGDDTNRALQ
KVDGSWTYFASDVAYHYHKLERGFNHMIVGLGADHAGYVKRLSGVVEALSGGDARIDIKLYNLVNLFRNGKPVKLSKRNG
DLITLDDVLESGITVSEIRFAMLTKSSEIVLDFDLDKFVRASYDNPLFYVQYAHARCSSLLRKRGPSAKCDAAMLVEKQE
LDLMVTLAKLPSLLKVIVVSGEVHKLTFYLHEVAERFHALWNAGMIENKFRFIIEDEPELTNARLILVKAVKNTLASVLK
VMKIEPAERM

Sequences:

>Translated_570_residues
MDLFLRLGNVLTEVVTSIFGVTLSEQVLLWNSPKKREYGDFSTAISFLIAKEVRLSLHEVACSIADGLRSFKDLFKNVSV
ASGGFINVFLTSDTWSEFLAAVSDDAGGYGFSDIGHAVPLNLEFVSANPTGPLHLGHIRGAVLFDIFAELLDKFGFSLTR
EYYINDAGKQIDLLVYSVFVRFCEQLRKKESDNFPSNCYAGDYIRDIASYLISTFPDSVKDTTELKSFSDTFREVILSLT
MDMIKSDLAKLGISYDCYVREKELHEGNYIEKVIAVLDEKGYLDEEELPSPKGKSGDWVERRQKVFLSTKFGDDTNRALQ
KVDGSWTYFASDVAYHYHKLERGFNHMIVGLGADHAGYVKRLSGVVEALSGGDARIDIKLYNLVNLFRNGKPVKLSKRNG
DLITLDDVLESGITVSEIRFAMLTKSSEIVLDFDLDKFVRASYDNPLFYVQYAHARCSSLLRKRGPSAKCDAAMLVEKQE
LDLMVTLAKLPSLLKVIVVSGEVHKLTFYLHEVAERFHALWNAGMIENKFRFIIEDEPELTNARLILVKAVKNTLASVLK
VMKIEPAERM
>Mature_570_residues
MDLFLRLGNVLTEVVTSIFGVTLSEQVLLWNSPKKREYGDFSTAISFLIAKEVRLSLHEVACSIADGLRSFKDLFKNVSV
ASGGFINVFLTSDTWSEFLAAVSDDAGGYGFSDIGHAVPLNLEFVSANPTGPLHLGHIRGAVLFDIFAELLDKFGFSLTR
EYYINDAGKQIDLLVYSVFVRFCEQLRKKESDNFPSNCYAGDYIRDIASYLISTFPDSVKDTTELKSFSDTFREVILSLT
MDMIKSDLAKLGISYDCYVREKELHEGNYIEKVIAVLDEKGYLDEEELPSPKGKSGDWVERRQKVFLSTKFGDDTNRALQ
KVDGSWTYFASDVAYHYHKLERGFNHMIVGLGADHAGYVKRLSGVVEALSGGDARIDIKLYNLVNLFRNGKPVKLSKRNG
DLITLDDVLESGITVSEIRFAMLTKSSEIVLDFDLDKFVRASYDNPLFYVQYAHARCSSLLRKRGPSAKCDAAMLVEKQE
LDLMVTLAKLPSLLKVIVVSGEVHKLTFYLHEVAERFHALWNAGMIENKFRFIIEDEPELTNARLILVKAVKNTLASVLK
VMKIEPAERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=625, Percent_Identity=20.16, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1788184, Length=593, Percent_Identity=23.4401349072513, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71985061, Length=623, Percent_Identity=21.8298555377207, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985068, Length=582, Percent_Identity=22.3367697594502, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320548, Length=559, Percent_Identity=23.2558139534884, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321883, Length=553, Percent_Identity=21.880650994575, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_NEOSM (Q2GEZ6)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_505950.1
- ProteinModelPortal:   Q2GEZ6
- STRING:   Q2GEZ6
- GeneID:   3931760
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0049
- TIGR:   NSE_0049
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   NSEN222891:NSE_0049-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64103; Mature: 64103

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFLRLGNVLTEVVTSIFGVTLSEQVLLWNSPKKREYGDFSTAISFLIAKEVRLSLHEV
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ACSIADGLRSFKDLFKNVSVASGGFINVFLTSDTWSEFLAAVSDDAGGYGFSDIGHAVPL
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCHHCCCCCCC
NLEFVSANPTGPLHLGHIRGAVLFDIFAELLDKFGFSLTREYYINDAGKQIDLLVYSVFV
EEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEHHHEECCCCCHHHHHHHHHHH
RFCEQLRKKESDNFPSNCYAGDYIRDIASYLISTFPDSVKDTTELKSFSDTFREVILSLT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MDMIKSDLAKLGISYDCYVREKELHEGNYIEKVIAVLDEKGYLDEEELPSPKGKSGDWVE
HHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHH
RRQKVFLSTKFGDDTNRALQKVDGSWTYFASDVAYHYHKLERGFNHMIVGLGADHAGYVK
HHHHEEEEECCCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
RLSGVVEALSGGDARIDIKLYNLVNLFRNGKPVKLSKRNGDLITLDDVLESGITVSEIRF
HHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHCCCCHHHHHH
AMLTKSSEIVLDFDLDKFVRASYDNPLFYVQYAHARCSSLLRKRGPSAKCDAAMLVEKQE
HHHCCCCCEEEEECHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LDLMVTLAKLPSLLKVIVVSGEVHKLTFYLHEVAERFHALWNAGMIENKFRFIIEDEPEL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
TNARLILVKAVKNTLASVLKVMKIEPAERM
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLFLRLGNVLTEVVTSIFGVTLSEQVLLWNSPKKREYGDFSTAISFLIAKEVRLSLHEV
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ACSIADGLRSFKDLFKNVSVASGGFINVFLTSDTWSEFLAAVSDDAGGYGFSDIGHAVPL
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCHHCCCCCCC
NLEFVSANPTGPLHLGHIRGAVLFDIFAELLDKFGFSLTREYYINDAGKQIDLLVYSVFV
EEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEHHHEECCCCCHHHHHHHHHHH
RFCEQLRKKESDNFPSNCYAGDYIRDIASYLISTFPDSVKDTTELKSFSDTFREVILSLT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MDMIKSDLAKLGISYDCYVREKELHEGNYIEKVIAVLDEKGYLDEEELPSPKGKSGDWVE
HHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHH
RRQKVFLSTKFGDDTNRALQKVDGSWTYFASDVAYHYHKLERGFNHMIVGLGADHAGYVK
HHHHEEEEECCCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
RLSGVVEALSGGDARIDIKLYNLVNLFRNGKPVKLSKRNGDLITLDDVLESGITVSEIRF
HHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHCCCCHHHHHH
AMLTKSSEIVLDFDLDKFVRASYDNPLFYVQYAHARCSSLLRKRGPSAKCDAAMLVEKQE
HHHCCCCCEEEEECHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LDLMVTLAKLPSLLKVIVVSGEVHKLTFYLHEVAERFHALWNAGMIENKFRFIIEDEPEL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
TNARLILVKAVKNTLASVLKVMKIEPAERM
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA