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The map label for this gene is coaD

Identifier: 88608096

GI number: 88608096

Start: 857539

End: 858024

Strand: Reverse

Name: coaD

Synonym: NSE_0970

Alternate gene names: 88608096

Gene position: 858024-857539 (Counterclockwise)

Preceding gene: 88608611

Following gene: 88608433

Centisome position: 99.89

GC content: 35.19

Gene sequence:

>486_bases
ATGAGGATCGGAGTATACGCTGGAACATTTGATCCAGTAACACTAGGTCACTTAGATATAATAAAGAAGGCACTCTTAGT
GGTGGACAAGCTTATAATAGCTGTTGCGGAGTGTACATCAAAAGCTCCGACATTTTCAAGTGAAAAGAGAAAGAGCTTCA
TTCAAAATTCTATAGCAGAAATTAAAGGAAAACTTGAGATAAAAACTTTCAAAGGTCTTTTAGTTGATTTTGTTAGGCAA
GAAAAAGGTAACACCATAGTACGAGGCCTAAGAGCCGTATCAGACTTCGAATATGAGTTCCAAATGAGTTGGGTAAATCA
TAAATTGGACGATAGAATAATAACAATATTCCTTCCAGCCTCACACGAAACACAATTTCTCTCATCAACTTTTGTCAAAC
AAGTAGCAATCCTTGGAGGAGACCTTTCTCAATTTTTACCGCATCAAATAATAAATGATGTAAGATCACATCTATTTAAA
CAATAA

Upstream 100 bases:

>100_bases
ACCACTTACTAGGAAAATAGTCATAGCAAATGGTAGTTTTCTAGATAAGAAACTGGATGATGAATTAAAAATCTTAGTAA
TAGAATTAATTGAGTAACAT

Downstream 100 bases:

>100_bases
ACACAAATCATTGGATTTGTGTCCTCTATTTATTCAGGTAAAAAAACATGTTCTCAACAGCAGATCTTGCAGCATCAAAG
ATTGATGGATCTATTTCTAT

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRIGVYAGTFDPVTLGHLDIIKKALLVVDKLIIAVAECTSKAPTFSSEKRKSFIQNSIAEIKGKLEIKTFKGLLVDFVRQ
EKGNTIVRGLRAVSDFEYEFQMSWVNHKLDDRIITIFLPASHETQFLSSTFVKQVAILGGDLSQFLPHQIINDVRSHLFK
Q

Sequences:

>Translated_161_residues
MRIGVYAGTFDPVTLGHLDIIKKALLVVDKLIIAVAECTSKAPTFSSEKRKSFIQNSIAEIKGKLEIKTFKGLLVDFVRQ
EKGNTIVRGLRAVSDFEYEFQMSWVNHKLDDRIITIFLPASHETQFLSSTFVKQVAILGGDLSQFLPHQIINDVRSHLFK
Q
>Mature_161_residues
MRIGVYAGTFDPVTLGHLDIIKKALLVVDKLIIAVAECTSKAPTFSSEKRKSFIQNSIAEIKGKLEIKTFKGLLVDFVRQ
EKGNTIVRGLRAVSDFEYEFQMSWVNHKLDDRIITIFLPASHETQFLSSTFVKQVAILGGDLSQFLPHQIINDVRSHLFK
Q

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=147, Percent_Identity=40.8163265306122, Blast_Score=130, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18192; Mature: 18192

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVYAGTFDPVTLGHLDIIKKALLVVDKLIIAVAECTSKAPTFSSEKRKSFIQNSIAE
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IKGKLEIKTFKGLLVDFVRQEKGNTIVRGLRAVSDFEYEFQMSWVNHKLDDRIITIFLPA
HHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEHHHHCCCCCCEEEEEEECC
SHETQFLSSTFVKQVAILGGDLSQFLPHQIINDVRSHLFKQ
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIGVYAGTFDPVTLGHLDIIKKALLVVDKLIIAVAECTSKAPTFSSEKRKSFIQNSIAE
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IKGKLEIKTFKGLLVDFVRQEKGNTIVRGLRAVSDFEYEFQMSWVNHKLDDRIITIFLPA
HHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEHHHHCCCCCCEEEEEEECC
SHETQFLSSTFVKQVAILGGDLSQFLPHQIINDVRSHLFKQ
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA