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The map label for this gene is dcd

Identifier: 88608088

GI number: 88608088

Start: 850940

End: 851497

Strand: Reverse

Name: dcd

Synonym: NSE_0964

Alternate gene names: 88608088

Gene position: 851497-850940 (Counterclockwise)

Preceding gene: 88608433

Following gene: 88608125

Centisome position: 99.13

GC content: 40.32

Gene sequence:

>558_bases
ATGCCCGTAATGCCTGATCAATGGATAAAGTCCAAGGCTTTAGAATCTAGGATGATAGAGCCGTTTGTGTCGTCCAAAAT
CTCTACTGGTGTTATTTCTTATGGGCTTTCCTCATACGGATACGATGCGAGAGTATCAAATAAATTCAAGATTTTTACGA
ATCTTGCAGTTTCGCAGGTCGATCCAAAAAACTTTGACGAATCAATGCTCATAGAGAGGACAGGAGATTTCTGTATTATT
CCACCGAACAGCTTTGCACTAGGGTGTACGATCGAATATTTTAGAGTTCCTCGTGGTGTCATAGTCATCTGTTTGGGGAA
GTCTACATATGCTAGGTGCGGAATAATAGTAAATGTAACGCCCCTTGAGCCTGAATGGGAAGGTCATGTTACCCTTGAGT
TTTCCAACACTACACCATTACCGGCAAAGATTTACTCAAACGAGGGTGTGTGTCAGATGATTTTTCTAAAGGGTAGCACT
AATTGTGATGTTTCATATAAAGATGCAAAAGGCAAATATATGGGTCAAGCTGGCATTACGCTTCCTATAGTAAAATAA

Upstream 100 bases:

>100_bases
AATAAAATTTGTGTGAGTCACATAAAGCCAGTTTGTATGGAGGTTTTAGTCATATTGATGTATAAGAGTTAGGTTACTTC
TAGGAACTTCAAACCTTAAA

Downstream 100 bases:

>100_bases
TACTCATTCTTTTTAATTTCTGCATGGACTTCTTTTCGAAAGCTATGAGAGTGCTAGACTTTTGTGGCTGTGATTACACA
CTCCTCTCTTGTAAAGTGAG

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MPVMPDQWIKSKALESRMIEPFVSSKISTGVISYGLSSYGYDARVSNKFKIFTNLAVSQVDPKNFDESMLIERTGDFCII
PPNSFALGCTIEYFRVPRGVIVICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYSNEGVCQMIFLKGST
NCDVSYKDAKGKYMGQAGITLPIVK

Sequences:

>Translated_185_residues
MPVMPDQWIKSKALESRMIEPFVSSKISTGVISYGLSSYGYDARVSNKFKIFTNLAVSQVDPKNFDESMLIERTGDFCII
PPNSFALGCTIEYFRVPRGVIVICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYSNEGVCQMIFLKGST
NCDVSYKDAKGKYMGQAGITLPIVK
>Mature_184_residues
PVMPDQWIKSKALESRMIEPFVSSKISTGVISYGLSSYGYDARVSNKFKIFTNLAVSQVDPKNFDESMLIERTGDFCIIP
PNSFALGCTIEYFRVPRGVIVICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYSNEGVCQMIFLKGSTN
CDVSYKDAKGKYMGQAGITLPIVK

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_NEOSM (Q2GCG8)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506828.1
- ProteinModelPortal:   Q2GCG8
- SMR:   Q2GCG8
- STRING:   Q2GCG8
- GeneID:   3931900
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0964
- TIGR:   NSE_0964
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- PhylomeDB:   Q2GCG8
- ProtClustDB:   PRK00416
- BioCyc:   NSEN222891:NSE_0964-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20470; Mature: 20339

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMPDQWIKSKALESRMIEPFVSSKISTGVISYGLSSYGYDARVSNKFKIFTNLAVSQV
CCCCCCHHHHHHHHHHHHHCHHHHCCCCCHHEECCCCCCCCCEEECCEEEEEEEEEEECC
DPKNFDESMLIERTGDFCIIPPNSFALGCTIEYFRVPRGVIVICLGKSTYARCGIIVNVT
CCCCCCCEEEEECCCCEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEEEEEE
PLEPEWEGHVTLEFSNTTPLPAKIYSNEGVCQMIFLKGSTNCDVSYKDAKGKYMGQAGIT
CCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEEEEECCCCCCEEEECCCCCEECCCCEE
LPIVK
EEEEC
>Mature Secondary Structure 
PVMPDQWIKSKALESRMIEPFVSSKISTGVISYGLSSYGYDARVSNKFKIFTNLAVSQV
CCCCCHHHHHHHHHHHHHCHHHHCCCCCHHEECCCCCCCCCEEECCEEEEEEEEEEECC
DPKNFDESMLIERTGDFCIIPPNSFALGCTIEYFRVPRGVIVICLGKSTYARCGIIVNVT
CCCCCCCEEEEECCCCEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEEEEEE
PLEPEWEGHVTLEFSNTTPLPAKIYSNEGVCQMIFLKGSTNCDVSYKDAKGKYMGQAGIT
CCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEEEEECCCCCCEEEECCCCCEECCCCEE
LPIVK
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA