Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 88608053

GI number: 88608053

Start: 581656

End: 582111

Strand: Reverse

Name: fabZ

Synonym: NSE_0663

Alternate gene names: 88608053

Gene position: 582111-581656 (Counterclockwise)

Preceding gene: 88608882

Following gene: 88608202

Centisome position: 67.77

GC content: 43.86

Gene sequence:

>456_bases
ATGGGTGCTGGGGATGTCTTGTTATCTCGTGAGGAGATAAAAAAGAGGATCCCTCATAGGGATCCTTTCCTTTTTTTGGA
CGAAGTAGTTAAAATTGACAGGGAGTCTCAGTCTATAGTTTGTCGTTGGAAGCCTGCTTCTAATGCTTGGTTTTTTCAAG
GGCACTTTCCTGGTTTCCCAATCACCCCGGGTGTATTGCTCATTGAGGCGCTTGCTCAGGCTGCTGGTGTATACGCTATG
ATGACTGTCGAGGAGAAATACCATAAGAAGCCGTTCTTTTTTGCCTCCATTGAGAAAGCGAAGTTCAAGAAGCCTGTTTT
GCCGGACACTCAACTTCTCCTAAATGCAACTTTATTAAAGAAATCAATGAATTTCTGGAAGTTTGAAGCTGGGGCTTATA
TAGCTGATGAGCTCTGTGTAGAGGCGACAATTATGGCGACAATCCAGTCAGAATGA

Upstream 100 bases:

>100_bases
CTCTGCACCTTCTGATATAAAATCCGATGTCAAAGGCAGTCCCTCTGAGCAGGCTGATTCAGGAACGAAGTCAGCTAAAT
CTAAGAAAAAGTAGACTGTG

Downstream 100 bases:

>100_bases
TGAATGCAATAAATTGTTCGTTCTCTTAATTTATTTGAACAAACAGGTATGTTATTCAGGTGCGCTTCTTCGTTTGAGCG
AGCTTTTCACAAGTGTCTGA

Product: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MGAGDVLLSREEIKKRIPHRDPFLFLDEVVKIDRESQSIVCRWKPASNAWFFQGHFPGFPITPGVLLIEALAQAAGVYAM
MTVEEKYHKKPFFFASIEKAKFKKPVLPDTQLLLNATLLKKSMNFWKFEAGAYIADELCVEATIMATIQSE

Sequences:

>Translated_151_residues
MGAGDVLLSREEIKKRIPHRDPFLFLDEVVKIDRESQSIVCRWKPASNAWFFQGHFPGFPITPGVLLIEALAQAAGVYAM
MTVEEKYHKKPFFFASIEKAKFKKPVLPDTQLLLNATLLKKSMNFWKFEAGAYIADELCVEATIMATIQSE
>Mature_150_residues
GAGDVLLSREEIKKRIPHRDPFLFLDEVVKIDRESQSIVCRWKPASNAWFFQGHFPGFPITPGVLLIEALAQAAGVYAMM
TVEEKYHKKPFFFASIEKAKFKKPVLPDTQLLLNATLLKKSMNFWKFEAGAYIADELCVEATIMATIQSE

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=144, Percent_Identity=38.1944444444444, Blast_Score=105, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17139; Mature: 17008

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGDVLLSREEIKKRIPHRDPFLFLDEVVKIDRESQSIVCRWKPASNAWFFQGHFPGFP
CCCCCCEECHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCC
ITPGVLLIEALAQAAGVYAMMTVEEKYHKKPFFFASIEKAKFKKPVLPDTQLLLNATLLK
CCHHHHHHHHHHHHCCEEEEEEEHHHHCCCCEEEEECCHHHCCCCCCCCHHHHHHHHHHH
KSMNFWKFEAGAYIADELCVEATIMATIQSE
HCCCCEEECCCCHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure 
GAGDVLLSREEIKKRIPHRDPFLFLDEVVKIDRESQSIVCRWKPASNAWFFQGHFPGFP
CCCCCEECHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCC
ITPGVLLIEALAQAAGVYAMMTVEEKYHKKPFFFASIEKAKFKKPVLPDTQLLLNATLLK
CCHHHHHHHHHHHHCCEEEEEEEHHHHCCCCEEEEECCHHHCCCCCCCCHHHHHHHHHHH
KSMNFWKFEAGAYIADELCVEATIMATIQSE
HCCCCEEECCCCHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA