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The map label for this gene is yaeL [C]

Identifier: 88607986

GI number: 88607986

Start: 640403

End: 641503

Strand: Reverse

Name: yaeL [C]

Synonym: NSE_0719

Alternate gene names: 88607986

Gene position: 641503-640403 (Counterclockwise)

Preceding gene: 88608108

Following gene: 88608737

Centisome position: 74.68

GC content: 39.6

Gene sequence:

>1101_bases
ATGGGTGGTTTACTTTTATATCTCGCATCCTTTCTGCTAGTGGTTTCTGTGATCGTCTTCGCGCATGAGTTTGGGCACTA
TATTTTTGCCAAAATGTTTGGTGTGAAAGTAGAGGAGTTTTCTATTGGATTTGGGAAAGAATTATTTGGCTTCAGTGATA
AGTCAGGAACCAGATGGAAGCTCTCTATGATTCCGGCTGGTGGGTATGTGAAAATGTTCGGAGATTTAGACAAGAGCAGT
GCTGTGGATTTTGAGAAAATTCATATGATGGATGATTGCATGAAAGCTCAAACCCTGAATTATAAACCTCTATATCAAAA
AGCACTTGTTATTTTTGGTGGTCCTTTTGCTAATTTTGTTTTTGCCTTTTTGGTTTTGTCTTTCCTATATGGTTATTTTG
GAAAAGTTACGGTTGAGCCAGTTGTAGCATCTGTTATTAGCGATAGTCCGGCAGCACATGCGGGATTCAGAGTTGGGGAC
AGGATCTTAACGATGAACAATAAGCCTATTGCAAGTTTCGACGAAATCAGAAAGTTCATTTACCTGAATCGTGATAGTGC
AGTATCTTTCACTGTGTTAAGGAATGGGGATGAGATATCTATGTCTGTAACTCCAAGGATTGAGGTTGGAGAAGATATAT
TCGGTAATCGTGAAGAGCTACCAAAGCTTGGAATAGAAGCATCAAAGATTCAGCGTAGCGAAATTGGAGTCGTGGGTGCA
ATGCGATTCTCTTTGATTGAGATTGGTAATGTTATTCATTCAACACTAAAGCTGCTCTGGCAGACGATTACAGGGAAAGC
TAAAACCAATGCTATAGGTGGTCCAATAAAAATTGCTAAATACTCCGGACAGTCCATGCGAATGGGATTCACCATGGTTT
TGTGGTTTATGGCAATGTTATCGATCAATCTTGGTTTGTTTAATCTTTTTCCTATACCGATGCTTGATGGTGGGCACCTG
CTTTTCTATTTGATTGAATGGATTAAGGGTGATAGAGTAGCAATTGGCTTTCAGCAATGGGCAGGAAGAGCAGGGATGTT
GTTATTGATAGCTATCCTTGTTTTTGCTGTTTTTAACGATATTCGTTTTGTTCTCAGGTAG

Upstream 100 bases:

>100_bases
TGCTGTCTATTTGGTGCTGGAGAATTATCTTTTCACCCTGTACATGGAATGACACTTCAGTGTAAGGTTTAGTTAGTCCT
GAGGTTAGTTTTAAAATTTT

Downstream 100 bases:

>100_bases
TTGATGCGAAAAAAACTTTTTTTGGTTTGGCTTCTTTTTTTGTCAAGGTTTTGCTTTGCGGATGAGGTAGTCGAAATTAG
AATTTCTGGTAATAAAAGAG

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGGLLLYLASFLLVVSVIVFAHEFGHYIFAKMFGVKVEEFSIGFGKELFGFSDKSGTRWKLSMIPAGGYVKMFGDLDKSS
AVDFEKIHMMDDCMKAQTLNYKPLYQKALVIFGGPFANFVFAFLVLSFLYGYFGKVTVEPVVASVISDSPAAHAGFRVGD
RILTMNNKPIASFDEIRKFIYLNRDSAVSFTVLRNGDEISMSVTPRIEVGEDIFGNREELPKLGIEASKIQRSEIGVVGA
MRFSLIEIGNVIHSTLKLLWQTITGKAKTNAIGGPIKIAKYSGQSMRMGFTMVLWFMAMLSINLGLFNLFPIPMLDGGHL
LFYLIEWIKGDRVAIGFQQWAGRAGMLLLIAILVFAVFNDIRFVLR

Sequences:

>Translated_366_residues
MGGLLLYLASFLLVVSVIVFAHEFGHYIFAKMFGVKVEEFSIGFGKELFGFSDKSGTRWKLSMIPAGGYVKMFGDLDKSS
AVDFEKIHMMDDCMKAQTLNYKPLYQKALVIFGGPFANFVFAFLVLSFLYGYFGKVTVEPVVASVISDSPAAHAGFRVGD
RILTMNNKPIASFDEIRKFIYLNRDSAVSFTVLRNGDEISMSVTPRIEVGEDIFGNREELPKLGIEASKIQRSEIGVVGA
MRFSLIEIGNVIHSTLKLLWQTITGKAKTNAIGGPIKIAKYSGQSMRMGFTMVLWFMAMLSINLGLFNLFPIPMLDGGHL
LFYLIEWIKGDRVAIGFQQWAGRAGMLLLIAILVFAVFNDIRFVLR
>Mature_365_residues
GGLLLYLASFLLVVSVIVFAHEFGHYIFAKMFGVKVEEFSIGFGKELFGFSDKSGTRWKLSMIPAGGYVKMFGDLDKSSA
VDFEKIHMMDDCMKAQTLNYKPLYQKALVIFGGPFANFVFAFLVLSFLYGYFGKVTVEPVVASVISDSPAAHAGFRVGDR
ILTMNNKPIASFDEIRKFIYLNRDSAVSFTVLRNGDEISMSVTPRIEVGEDIFGNREELPKLGIEASKIQRSEIGVVGAM
RFSLIEIGNVIHSTLKLLWQTITGKAKTNAIGGPIKIAKYSGQSMRMGFTMVLWFMAMLSINLGLFNLFPIPMLDGGHLL
FYLIEWIKGDRVAIGFQQWAGRAGMLLLIAILVFAVFNDIRFVLR

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=230, Percent_Identity=33.4782608695652, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40784; Mature: 40653

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGLLLYLASFLLVVSVIVFAHEFGHYIFAKMFGVKVEEFSIGFGKELFGFSDKSGTRWK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCCCCCEEE
LSMIPAGGYVKMFGDLDKSSAVDFEKIHMMDDCMKAQTLNYKPLYQKALVIFGGPFANFV
EEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEEECCHHHHHH
FAFLVLSFLYGYFGKVTVEPVVASVISDSPAAHAGFRVGDRILTMNNKPIASFDEIRKFI
HHHHHHHHHHHHHCCEEHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHE
YLNRDSAVSFTVLRNGDEISMSVTPRIEVGEDIFGNREELPKLGIEASKIQRSEIGVVGA
EECCCCCEEEEEEECCCEEEEEECCCEECCCHHCCCHHHHHHCCCCHHHHHHHHCCCHHH
MRFSLIEIGNVIHSTLKLLWQTITGKAKTNAIGGPIKIAKYSGQSMRMGFTMVLWFMAML
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
SINLGLFNLFPIPMLDGGHLLFYLIEWIKGDRVAIGFQQWAGRAGMLLLIAILVFAVFND
HHCCCHHEECCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHH
IRFVLR
HHHHCC
>Mature Secondary Structure 
GGLLLYLASFLLVVSVIVFAHEFGHYIFAKMFGVKVEEFSIGFGKELFGFSDKSGTRWK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCCCCCEEE
LSMIPAGGYVKMFGDLDKSSAVDFEKIHMMDDCMKAQTLNYKPLYQKALVIFGGPFANFV
EEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEEECCHHHHHH
FAFLVLSFLYGYFGKVTVEPVVASVISDSPAAHAGFRVGDRILTMNNKPIASFDEIRKFI
HHHHHHHHHHHHHCCEEHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHE
YLNRDSAVSFTVLRNGDEISMSVTPRIEVGEDIFGNREELPKLGIEASKIQRSEIGVVGA
EECCCCCEEEEEEECCCEEEEEECCCEECCCHHCCCHHHHHHCCCCHHHHHHHHCCCHHH
MRFSLIEIGNVIHSTLKLLWQTITGKAKTNAIGGPIKIAKYSGQSMRMGFTMVLWFMAML
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
SINLGLFNLFPIPMLDGGHLLFYLIEWIKGDRVAIGFQQWAGRAGMLLLIAILVFAVFND
HHCCCHHEECCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHH
IRFVLR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]