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The map label for this gene is ctaA

Identifier: 88607965

GI number: 88607965

Start: 756879

End: 757856

Strand: Reverse

Name: ctaA

Synonym: NSE_0855

Alternate gene names: 88607965

Gene position: 757856-756879 (Counterclockwise)

Preceding gene: 88608766

Following gene: 88608255

Centisome position: 88.22

GC content: 38.55

Gene sequence:

>978_bases
ATGTCTTATAGAACATGGCTTGCTGTCTGTATACTTCTGATATTGTCAATGGTGTCAATTGGTGGTTTTACGAGATTAAC
TGAGTCTGGATTATCAATTACTGAATGGAAGCCAGTAACTGGAGTGATTCCACCACTTAGCAAGAATGCATGGCAAAAGG
AGTTTGATAAGTACAAAAATACTCCTGAGTATAAAGTACGTCACTTTTCCATTTCCTACGCTGAGTTTCAGTTCATTTAC
TTGGTAGAATATTTTCACCGGCTTGTTGGAAGGATACTGGGGTTAGTCTTCTTTATAGGTTTGGTTTATTTTTTCGTTGT
AGGTAACCTAGCTAGGGAGTCACGATTAAGACTGTGCTTTGCTTTGGTCCTGGGAGTAATACAAGGATTTGTTGGTTGGT
ACATGGTTAAAAGCGGTTTATTGGATGTGCCAGCTGTTAGTCACTATAGACTTGCTTTGCATCTTTTTTGCGCATCTTTA
CTTTTCATGGTGTTGGTTTATGAATTTCTATCACCGACAGTAATCAAGGGATCTGTGTTCAAATGGCACTTAGTTGGATG
CTCACTTATGTTCCTCTTGAGTATGCAAATTATACTTGGAGGCCTTGTAGCTGGGCTGAAAGCTGGCCTCATATGCAGTA
CATTTCCTCTCATGAATGGAGAATTTTTTCCCGCTGAGATATTTCATGAACTAAGTTTAAATTGTTTCAATGATCCAGTT
GCTGTGCAGTTTTTGCATAGAATGAGTGCTTTCTTACTGACCTTTATATGTCTTGTATGTCTGGTAATTTCATTCTTTTA
TGATAGAGCCTTTCGTGCGAGAGTTTTTTTGGTAGCATCGATGATGTTACTGCAAATGTTTTTCGGTGTTCTAACGCTGC
TTTTCCATATACCAATTGATATTGCGTTGTTGCATCAAATAATGGCTTTCATTCTGCTTGGTATTTGTGTTTCCTTTTTG
AGGGTGCGGTCCGGATAA

Upstream 100 bases:

>100_bases
AGAGCTTGCTTCTCCTTAGGTGTTTGTACGTGCGAACTTTTTCATTGCACAGTTTTATGTGATCATTACTGTCTTGAAGT
TGCTAAAGAGTCTAATTGCG

Downstream 100 bases:

>100_bases
AATTTCGTATTGTCAAGAGCTGTGCCGAAGGGTTGCTGGGTCTCATTTACCTGGGACATACTCATTGAACGTCTTCGTTG
CGATTAAAATCATCACAACG

Product: putative cytochrome oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSYRTWLAVCILLILSMVSIGGFTRLTESGLSITEWKPVTGVIPPLSKNAWQKEFDKYKNTPEYKVRHFSISYAEFQFIY
LVEYFHRLVGRILGLVFFIGLVYFFVVGNLARESRLRLCFALVLGVIQGFVGWYMVKSGLLDVPAVSHYRLALHLFCASL
LFMVLVYEFLSPTVIKGSVFKWHLVGCSLMFLLSMQIILGGLVAGLKAGLICSTFPLMNGEFFPAEIFHELSLNCFNDPV
AVQFLHRMSAFLLTFICLVCLVISFFYDRAFRARVFLVASMMLLQMFFGVLTLLFHIPIDIALLHQIMAFILLGICVSFL
RVRSG

Sequences:

>Translated_325_residues
MSYRTWLAVCILLILSMVSIGGFTRLTESGLSITEWKPVTGVIPPLSKNAWQKEFDKYKNTPEYKVRHFSISYAEFQFIY
LVEYFHRLVGRILGLVFFIGLVYFFVVGNLARESRLRLCFALVLGVIQGFVGWYMVKSGLLDVPAVSHYRLALHLFCASL
LFMVLVYEFLSPTVIKGSVFKWHLVGCSLMFLLSMQIILGGLVAGLKAGLICSTFPLMNGEFFPAEIFHELSLNCFNDPV
AVQFLHRMSAFLLTFICLVCLVISFFYDRAFRARVFLVASMMLLQMFFGVLTLLFHIPIDIALLHQIMAFILLGICVSFL
RVRSG
>Mature_324_residues
SYRTWLAVCILLILSMVSIGGFTRLTESGLSITEWKPVTGVIPPLSKNAWQKEFDKYKNTPEYKVRHFSISYAEFQFIYL
VEYFHRLVGRILGLVFFIGLVYFFVVGNLARESRLRLCFALVLGVIQGFVGWYMVKSGLLDVPAVSHYRLALHLFCASLL
FMVLVYEFLSPTVIKGSVFKWHLVGCSLMFLLSMQIILGGLVAGLKAGLICSTFPLMNGEFFPAEIFHELSLNCFNDPVA
VQFLHRMSAFLLTFICLVCLVISFFYDRAFRARVFLVASMMLLQMFFGVLTLLFHIPIDIALLHQIMAFILLGICVSFLR
VRSG

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=331, Percent_Identity=34.7432024169184, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI17921987, Length=319, Percent_Identity=33.8557993730408, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17536069, Length=330, Percent_Identity=35.7575757575758, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6320989, Length=363, Percent_Identity=35.8126721763085, Blast_Score=189, Evalue=6e-49,
Organism=Drosophila melanogaster, GI19922860, Length=322, Percent_Identity=36.3354037267081, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_NEOSM (Q2GCS4)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506722.1
- STRING:   Q2GCS4
- GeneID:   3931409
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0855
- TIGR:   NSE_0855
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q2GCS4
- ProtClustDB:   CLSK2776142
- BioCyc:   NSEN222891:NSE_0855-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 36979; Mature: 36848

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: BINDING 305-305

Signals:

None

Transmembrane regions:

HASH(0xb523150)-; HASH(0x1147bddc)-; HASH(0x10565078)-; HASH(0x1041d838)-; HASH(0x112c9064)-; HASH(0x11291328)-; HASH(0x1172895c)-;

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRTWLAVCILLILSMVSIGGFTRLTESGLSITEWKPVTGVIPPLSKNAWQKEFDKYKN
CCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
TPEYKVRHFSISYAEFQFIYLVEYFHRLVGRILGLVFFIGLVYFFVVGNLARESRLRLCF
CCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVLGVIQGFVGWYMVKSGLLDVPAVSHYRLALHLFCASLLFMVLVYEFLSPTVIKGSVF
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHH
KWHLVGCSLMFLLSMQIILGGLVAGLKAGLICSTFPLMNGEFFPAEIFHELSLNCFNDPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHH
AVQFLHRMSAFLLTFICLVCLVISFFYDRAFRARVFLVASMMLLQMFFGVLTLLFHIPID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
IALLHQIMAFILLGICVSFLRVRSG
HHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SYRTWLAVCILLILSMVSIGGFTRLTESGLSITEWKPVTGVIPPLSKNAWQKEFDKYKN
CHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC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HHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA