Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 88607956

GI number: 88607956

Start: 363841

End: 364764

Strand: Direct

Name: xerC [H]

Synonym: NSE_0447

Alternate gene names: 88607956

Gene position: 363841-364764 (Clockwise)

Preceding gene: 88608593

Following gene: 88608385

Centisome position: 42.36

GC content: 41.02

Gene sequence:

>924_bases
GTGGAGTGTAAAATTGATCCCTCAGTTTTCACCATTCTTGATGAGTGGACAAGATGGTTAGGTGGTGTAAAGTGCTTTTC
CAGTAATACGTTAGTTGCCTATAGCAGGGATTTAATGGCTTTTTTGGATTTCCTTTCTACTTTCAGAGGGGAACCTGTGC
GTTTTACTAGCTTGGACTGCATAGATAGTAAGGATCTACGTGCCTGGCTTGCAAGCAGAAGAAAGAACTCTATTTCTTTC
CGCACGAATGCGAGGGCTTTGTCTTCAGTAAAGAGTTTTTTTAAGTACCTTGCAAAACATAAGGGAATTATAAACGAAGA
TGTCTTAGGGGTTGTATTGAGGTTCAAGCCAAATACGCTACCACGTTCTCTGACTTTTAAAGAAATAATAGAATTAATCG
AGAAATTTTCTTTTTTAAAGACAAGTTGGATAGTAAAGAGGAATATTGCTCTGTGCTACTTGTTATATGGTTCTGGCTTA
AGGATTAGTGAAGCGTTAAGTCTAACAGTCGCGGACCTTACCAATAGTGAAATCAAGATAATAGGTAAAGGTGGTAGGGA
GAGGATGATCCGCTTGTTACCTATAGTTCGCGTTGCATTATCAGATTACATTGCTTCATGCCCGTTTCAGCCGGATGCCG
GAGGTTTCCTTTTTTTGGATCGAAACGGAAACAAGCTTTGTAGGACCGCTGTAGCAAGAGCCTTTCTCTCAATTCGCAGA
GGATTCAATCTCCCGGATCATATCACGCCGCACGCGCTGAGACACAGCTTTGCTACGCATTTACTTCAGGAAGGTGTTGG
TGTTCGTAAAATACAAGAATTATTAGGGCATGCTTCACTTGCGAGCACTGAGGTCTATACAAAACTTAATGCTGAATCGC
TTATGGAAAAGTATAAGCAATTCTGCTTGAGAGATAGGGATTGA

Upstream 100 bases:

>100_bases
CTTAACCTTAAATACTACTTTACCTGAATTTAACTTTTACTTAGAGCCTATTTGCTTCTTAAAAAAGGTATATCGGTAGT
GCAAGTTTTTCCTGTGAATC

Downstream 100 bases:

>100_bases
ACTCTATCTAAGGGGGCTGAATTATGCAAAGTTAGCTATAATCAGGGTGCTTTTTATTATGATGTCCCTGTTTTTTGCAC
ACTTTTAAGCTTGTATCAAG

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MECKIDPSVFTILDEWTRWLGGVKCFSSNTLVAYSRDLMAFLDFLSTFRGEPVRFTSLDCIDSKDLRAWLASRRKNSISF
RTNARALSSVKSFFKYLAKHKGIINEDVLGVVLRFKPNTLPRSLTFKEIIELIEKFSFLKTSWIVKRNIALCYLLYGSGL
RISEALSLTVADLTNSEIKIIGKGGRERMIRLLPIVRVALSDYIASCPFQPDAGGFLFLDRNGNKLCRTAVARAFLSIRR
GFNLPDHITPHALRHSFATHLLQEGVGVRKIQELLGHASLASTEVYTKLNAESLMEKYKQFCLRDRD

Sequences:

>Translated_307_residues
MECKIDPSVFTILDEWTRWLGGVKCFSSNTLVAYSRDLMAFLDFLSTFRGEPVRFTSLDCIDSKDLRAWLASRRKNSISF
RTNARALSSVKSFFKYLAKHKGIINEDVLGVVLRFKPNTLPRSLTFKEIIELIEKFSFLKTSWIVKRNIALCYLLYGSGL
RISEALSLTVADLTNSEIKIIGKGGRERMIRLLPIVRVALSDYIASCPFQPDAGGFLFLDRNGNKLCRTAVARAFLSIRR
GFNLPDHITPHALRHSFATHLLQEGVGVRKIQELLGHASLASTEVYTKLNAESLMEKYKQFCLRDRD
>Mature_307_residues
MECKIDPSVFTILDEWTRWLGGVKCFSSNTLVAYSRDLMAFLDFLSTFRGEPVRFTSLDCIDSKDLRAWLASRRKNSISF
RTNARALSSVKSFFKYLAKHKGIINEDVLGVVLRFKPNTLPRSLTFKEIIELIEKFSFLKTSWIVKRNIALCYLLYGSGL
RISEALSLTVADLTNSEIKIIGKGGRERMIRLLPIVRVALSDYIASCPFQPDAGGFLFLDRNGNKLCRTAVARAFLSIRR
GFNLPDHITPHALRHSFATHLLQEGVGVRKIQELLGHASLASTEVYTKLNAESLMEKYKQFCLRDRD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=303, Percent_Identity=30.6930693069307, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=30.0341296928328, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34881; Mature: 34881

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECKIDPSVFTILDEWTRWLGGVKCFSSNTLVAYSRDLMAFLDFLSTFRGEPVRFTSLDC
CCCCCCHHHHHHHHHHHHHHCCEEEECCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECC
IDSKDLRAWLASRRKNSISFRTNARALSSVKSFFKYLAKHKGIINEDVLGVVLRFKPNTL
CCCHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCC
PRSLTFKEIIELIEKFSFLKTSWIVKRNIALCYLLYGSGLRISEALSLTVADLTNSEIKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHEECCCCCCEEE
IGKGGRERMIRLLPIVRVALSDYIASCPFQPDAGGFLFLDRNGNKLCRTAVARAFLSIRR
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
GFNLPDHITPHALRHSFATHLLQEGVGVRKIQELLGHASLASTEVYTKLNAESLMEKYKQ
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
FCLRDRD
HHCCCCC
>Mature Secondary Structure
MECKIDPSVFTILDEWTRWLGGVKCFSSNTLVAYSRDLMAFLDFLSTFRGEPVRFTSLDC
CCCCCCHHHHHHHHHHHHHHCCEEEECCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECC
IDSKDLRAWLASRRKNSISFRTNARALSSVKSFFKYLAKHKGIINEDVLGVVLRFKPNTL
CCCHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCC
PRSLTFKEIIELIEKFSFLKTSWIVKRNIALCYLLYGSGLRISEALSLTVADLTNSEIKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHEECCCCCCEEE
IGKGGRERMIRLLPIVRVALSDYIASCPFQPDAGGFLFLDRNGNKLCRTAVARAFLSIRR
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
GFNLPDHITPHALRHSFATHLLQEGVGVRKIQELLGHASLASTEVYTKLNAESLMEKYKQ
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
FCLRDRD
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]