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The map label for this gene is iscU [H]

Identifier: 88607576

GI number: 88607576

Start: 696821

End: 697213

Strand: Direct

Name: iscU [H]

Synonym: APH_0675

Alternate gene names: 88607576

Gene position: 696821-697213 (Clockwise)

Preceding gene: 88606709

Following gene: 88607054

Centisome position: 47.36

GC content: 44.53

Gene sequence:

>393_bases
ATGAGTTATAGTGATGCTGTATTAAATCGCTGCAAGGCTCCTCAGAATGTGGGTTCGCTACCTAAGGATGATATTTCTGT
TGGTACGGGCTTGGTGGGTGCGCCGAGTTGTGGTGACGTGATGAAGTTGCAAATTAGGGTGGACGAGAACGGGAAGATAG
TCGATGCCAAGTTCAAGACCTTTGGATGTGGAGCAGCAATAGCAGCGAGTGAATTGGCTACTGAGAGGATAATGGGTAAG
ACTATAGACGAGGCATCTTTGTTGAAGAATACTGTTCTTGCTAAGGAGCTTTCTCTTCCTCCGGTAAAGATACATTGCTC
TATATTGGCTGAAGATGCTGTGAAGGCTGCTATTAATGATTATCGTAAAAAGCAAGAAGCGGTAGGCAATTAA

Upstream 100 bases:

>100_bases
TGTACGCAGGCTGAGGGATATTAGTCCTTTATGGGAGATGGTGCAGGAAGGTACTAACCTGAGTACGATTAAGTGGGATG
TATAGTAAGTAGAGGTTTTT

Downstream 100 bases:

>100_bases
TATGGATAATAGCGCTGTTCAGAATATGGATGATAAAGGCAGGGAGGTTCCTGTTGTTATTACTGATGCCGCGCTCCGTA
GAATGAAGGAATTACTGCTT

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MSYSDAVLNRCKAPQNVGSLPKDDISVGTGLVGAPSCGDVMKLQIRVDENGKIVDAKFKTFGCGAAIAASELATERIMGK
TIDEASLLKNTVLAKELSLPPVKIHCSILAEDAVKAAINDYRKKQEAVGN

Sequences:

>Translated_130_residues
MSYSDAVLNRCKAPQNVGSLPKDDISVGTGLVGAPSCGDVMKLQIRVDENGKIVDAKFKTFGCGAAIAASELATERIMGK
TIDEASLLKNTVLAKELSLPPVKIHCSILAEDAVKAAINDYRKKQEAVGN
>Mature_129_residues
SYSDAVLNRCKAPQNVGSLPKDDISVGTGLVGAPSCGDVMKLQIRVDENGKIVDAKFKTFGCGAAIAASELATERIMGKT
IDEASLLKNTVLAKELSLPPVKIHCSILAEDAVKAAINDYRKKQEAVGN

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=124, Percent_Identity=67.741935483871, Blast_Score=176, Evalue=5e-45,
Organism=Homo sapiens, GI24307953, Length=123, Percent_Identity=68.2926829268293, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788878, Length=127, Percent_Identity=62.2047244094488, Blast_Score=172, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17543474, Length=123, Percent_Identity=69.1056910569106, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6325122, Length=124, Percent_Identity=62.0967741935484, Blast_Score=157, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6324800, Length=124, Percent_Identity=59.6774193548387, Blast_Score=152, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355597, Length=124, Percent_Identity=70.9677419354839, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 13718; Mature: 13587

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSDAVLNRCKAPQNVGSLPKDDISVGTGLVGAPSCGDVMKLQIRVDENGKIVDAKFKT
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCC
FGCGAAIAASELATERIMGKTIDEASLLKNTVLAKELSLPPVKIHCSILAEDAVKAAIND
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
YRKKQEAVGN
HHHHHHHCCC
>Mature Secondary Structure 
SYSDAVLNRCKAPQNVGSLPKDDISVGTGLVGAPSCGDVMKLQIRVDENGKIVDAKFKT
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCC
FGCGAAIAASELATERIMGKTIDEASLLKNTVLAKELSLPPVKIHCSILAEDAVKAAIND
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
YRKKQEAVGN
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]