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The map label for this gene is ruvC [H]

Identifier: 88607505

GI number: 88607505

Start: 1361204

End: 1361434

Strand: Reverse

Name: ruvC [H]

Synonym: APH_1294

Alternate gene names: 88607505

Gene position: 1361434-1361204 (Counterclockwise)

Preceding gene: 88606753

Following gene: 88606804

Centisome position: 92.53

GC content: 37.66

Gene sequence:

>231_bases
TTGGGCTGTTGTACTAAAAAACCGTCTGGTTCTCTTTCTCTGATTGACTCCGGCACTATCTGTACTCTTTCTTCTGCTGA
TCTTAATGATAAGCTTTCTTACATCTTCTCTACTCTTACTGATATTATTCAGAAGTTTTCCATCTCTGTGGCTTCTAATG
TTTTTGTTAATTTAAACCCAAGGCCTCTATGTTCCTTTGTTATGCTAGGGCTGTTCCTATCCTTGTTTTGA

Upstream 100 bases:

>100_bases
GGGAATTGCAGGCCTTAGAAGATGGGGGTATGTGAAGTGGTTCAGGTTGGGTAAGCCATAACCACGGGAAATGTACCCTG
TGATGGGTTGAAGACGCGGG

Downstream 100 bases:

>100_bases
AGATTTTCCTTTCATAACACGATGATACATAAACAAGAATTGCATTACACCACCTAACTCCAAAAGACTTCAATACAAGA
CAACAACTGCACGCGCCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 76; Mature: 75

Protein sequence:

>76_residues
MGCCTKKPSGSLSLIDSGTICTLSSADLNDKLSYIFSTLTDIIQKFSISVASNVFVNLNPRPLCSFVMLGLFLSLF

Sequences:

>Translated_76_residues
MGCCTKKPSGSLSLIDSGTICTLSSADLNDKLSYIFSTLTDIIQKFSISVASNVFVNLNPRPLCSFVMLGLFLSLF
>Mature_75_residues
GCCTKKPSGSLSLIDSGTICTLSSADLNDKLSYIFSTLTDIIQKFSISVASNVFVNLNPRPLCSFVMLGLFLSLF

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 8186; Mature: 8054

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCCTKKPSGSLSLIDSGTICTLSSADLNDKLSYIFSTLTDIIQKFSISVASNVFVNLNP
CCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCC
RPLCSFVMLGLFLSLF
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GCCTKKPSGSLSLIDSGTICTLSSADLNDKLSYIFSTLTDIIQKFSISVASNVFVNLNP
CCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCC
RPLCSFVMLGLFLSLF
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA