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The map label for this gene is coaD [H]

Identifier: 88607052

GI number: 88607052

Start: 673178

End: 673684

Strand: Direct

Name: coaD [H]

Synonym: APH_0650

Alternate gene names: 88607052

Gene position: 673178-673684 (Clockwise)

Preceding gene: 88607316

Following gene: 88607815

Centisome position: 45.75

GC content: 40.24

Gene sequence:

>507_bases
GTGACTAAGAGATTAGGGATATATCCCGGGACTTTTGATCCCATAACTTTTGGACATATAGATATAATCAAGAGAGCATG
TACTCTTGTTGATGAGTTGGTTATTGGTGTAGCAAGGAGTGTACAGAAGAGCACTATTTTTTCAGCAGAATTGCGTGCCG
AAATGATACAGCGCGAGATGCACGTTTTGGAATGCAAGAGCGTTGTGAAGGTTGAGGTTTTCGATGGTTTGTTAACTGCG
TTTGCCAAACAAAAAAAGGCTCTAATGATCATTAGAGGGTTACGTGCAGTTACAGATTTTGATTATGAATTTCAGATGAG
CTGGATAAATTACAAATTGACACCAGGTATCGAGACTGTTTTCCTCCCCGCGGCAGAGGAGACTCAGTTTATCTCTTCGA
GTTTTGTCAAGGAAGTTGCAAGATTAGGAGGAGATGTGAGTGTATTTGTGCCACATAATGTTCATGAGCACCTGAGAGAT
TTCTATAATAATTCTTCTGCGAAGTAA

Upstream 100 bases:

>100_bases
TATATGCTCAAGCATCAGCATTCAAGAAAAATAAACTTGAAAAATAGGTAGATAATTCTTTTATCATCCTGGATAATAGT
AACTCTGTGGAGTTAAAGCC

Downstream 100 bases:

>100_bases
GTAATAGTATCTAGAATAACAACACTATTTTTTCAGCAGAATTGCGTGCCGAAATGATACAGCGCGAGATGCACGTTTTG
GAATGCAAGAGCGTTGTGAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTKRLGIYPGTFDPITFGHIDIIKRACTLVDELVIGVARSVQKSTIFSAELRAEMIQREMHVLECKSVVKVEVFDGLLTA
FAKQKKALMIIRGLRAVTDFDYEFQMSWINYKLTPGIETVFLPAAEETQFISSSFVKEVARLGGDVSVFVPHNVHEHLRD
FYNNSSAK

Sequences:

>Translated_168_residues
MTKRLGIYPGTFDPITFGHIDIIKRACTLVDELVIGVARSVQKSTIFSAELRAEMIQREMHVLECKSVVKVEVFDGLLTA
FAKQKKALMIIRGLRAVTDFDYEFQMSWINYKLTPGIETVFLPAAEETQFISSSFVKEVARLGGDVSVFVPHNVHEHLRD
FYNNSSAK
>Mature_167_residues
TKRLGIYPGTFDPITFGHIDIIKRACTLVDELVIGVARSVQKSTIFSAELRAEMIQREMHVLECKSVVKVEVFDGLLTAF
AKQKKALMIIRGLRAVTDFDYEFQMSWINYKLTPGIETVFLPAAEETQFISSSFVKEVARLGGDVSVFVPHNVHEHLRDF
YNNSSAK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=48.1012658227848, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 19002; Mature: 18871

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRLGIYPGTFDPITFGHIDIIKRACTLVDELVIGVARSVQKSTIFSAELRAEMIQREM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVLECKSVVKVEVFDGLLTAFAKQKKALMIIRGLRAVTDFDYEFQMSWINYKLTPGIETV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEE
FLPAAEETQFISSSFVKEVARLGGDVSVFVPHNVHEHLRDFYNNSSAK
EECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKRLGIYPGTFDPITFGHIDIIKRACTLVDELVIGVARSVQKSTIFSAELRAEMIQREM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVLECKSVVKVEVFDGLLTAFAKQKKALMIIRGLRAVTDFDYEFQMSWINYKLTPGIETV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEE
FLPAAEETQFISSSFVKEVARLGGDVSVFVPHNVHEHLRDFYNNSSAK
EECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA