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The map label for this gene is pdxJ

Identifier: 88607034

GI number: 88607034

Start: 829692

End: 830393

Strand: Reverse

Name: pdxJ

Synonym: APH_0790

Alternate gene names: 88607034

Gene position: 830393-829692 (Counterclockwise)

Preceding gene: 88607801

Following gene: 88607295

Centisome position: 56.44

GC content: 43.73

Gene sequence:

>702_bases
GTGCAGCTTGGTGTCAACGTTGATCATGTGGCAACACTTCGCAATCTCAGGGGCACAACATATCCCAGTATAGTTGAGTT
GGCGAATATAGCGGTAGAACATGGCGCAGATTTCATCACTGTGCATTTGAGAGAAGATAGACGACATGTTCGAGATGATG
ATCTGTATGCGTTGAAGAAGCATGTGAATGTGCCTATAAACTTAGAAATGGCAGCTACTGAAGAAATGCTGGCCATAGCC
AAAGAATTATCTCCAGAATTTGTATGTCTGGTTCCGGAGAAAAGGGAAGAGGTGACTACGGAATCCGGTCTGGATACTAA
ATTACTTTATGACACCCGTTTATTTATTATTAGTGAGCTGCAAAGGCATGGCATAAAAGTAACGTTGTTTCTCGATCCTA
GCGAAGAAGACATTGCCTGTGCGAAAAGAATGAACGTTGACAAGATAGAGCTTCATGTCGGTGCGTATTGTATCAGTCGT
GCCCCGCAGGAGTTGGAAATGATTACACGCGCAGCGCAACTAGTACACGAAGCAGGGATGATATGTCACGCAGGACATGG
CATAGATTATGAATGTGCCGCAGCTATATCAAAGGTGAAGCATATCACCGCAATAAATGTTGGCCATTTTCTTGTTTGTG
AGGCTATAACACAGGGTATGGGGAATGCGGTACGGAAAATGAAGGATATAATAACATCCTGA

Upstream 100 bases:

>100_bases
ATGTTTATATTACGTTGTGTTGCGATAATCGTGTAACATATTTATGTGTAGTTCTTAAAGTCTTTAGGTTACTTAAGCAG
TATTTTCAAGGAGGATTTCA

Downstream 100 bases:

>100_bases
TAGAAATGCTTAGAGAGGAAGTGTAACATCAAGTAAAATGAGATGTGGGGGAACTGTGAAGTCTGGGTGCGTAAATGCTG
AGTTGTACGGTATGCTGACG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MQLGVNVDHVATLRNLRGTTYPSIVELANIAVEHGADFITVHLREDRRHVRDDDLYALKKHVNVPINLEMAATEEMLAIA
KELSPEFVCLVPEKREEVTTESGLDTKLLYDTRLFIISELQRHGIKVTLFLDPSEEDIACAKRMNVDKIELHVGAYCISR
APQELEMITRAAQLVHEAGMICHAGHGIDYECAAAISKVKHITAINVGHFLVCEAITQGMGNAVRKMKDIITS

Sequences:

>Translated_233_residues
MQLGVNVDHVATLRNLRGTTYPSIVELANIAVEHGADFITVHLREDRRHVRDDDLYALKKHVNVPINLEMAATEEMLAIA
KELSPEFVCLVPEKREEVTTESGLDTKLLYDTRLFIISELQRHGIKVTLFLDPSEEDIACAKRMNVDKIELHVGAYCISR
APQELEMITRAAQLVHEAGMICHAGHGIDYECAAAISKVKHITAINVGHFLVCEAITQGMGNAVRKMKDIITS
>Mature_233_residues
MQLGVNVDHVATLRNLRGTTYPSIVELANIAVEHGADFITVHLREDRRHVRDDDLYALKKHVNVPINLEMAATEEMLAIA
KELSPEFVCLVPEKREEVTTESGLDTKLLYDTRLFIISELQRHGIKVTLFLDPSEEDIACAKRMNVDKIELHVGAYCISR
APQELEMITRAAQLVHEAGMICHAGHGIDYECAAAISKVKHITAINVGHFLVCEAITQGMGNAVRKMKDIITS

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=46.3519313304721, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_ANAPZ (Q2GJT4)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505367.1
- ProteinModelPortal:   Q2GJT4
- SMR:   Q2GJT4
- STRING:   Q2GJT4
- GeneID:   3930823
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0790
- NMPDR:   fig|212042.5.peg.756
- TIGR:   APH_0790
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- PhylomeDB:   Q2GJT4
- ProtClustDB:   PRK05265
- BioCyc:   APHA212042:APH_0790-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 25963; Mature: 25963

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: ACT_SITE 42-42 ACT_SITE 69-69 ACT_SITE 186-186 BINDING 6-6 BINDING 17-17 BINDING 44-44 BINDING 49-49 BINDING 99-99 BINDING 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLGVNVDHVATLRNLRGTTYPSIVELANIAVEHGADFITVHLREDRRHVRDDDLYALKK
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
HVNVPINLEMAATEEMLAIAKELSPEFVCLVPEKREEVTTESGLDTKLLYDTRLFIISEL
HCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHH
QRHGIKVTLFLDPSEEDIACAKRMNVDKIELHVGAYCISRAPQELEMITRAAQLVHEAGM
HHCCEEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
ICHAGHGIDYECAAAISKVKHITAINVGHFLVCEAITQGMGNAVRKMKDIITS
EEECCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLGVNVDHVATLRNLRGTTYPSIVELANIAVEHGADFITVHLREDRRHVRDDDLYALKK
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
HVNVPINLEMAATEEMLAIAKELSPEFVCLVPEKREEVTTESGLDTKLLYDTRLFIISEL
HCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHH
QRHGIKVTLFLDPSEEDIACAKRMNVDKIELHVGAYCISRAPQELEMITRAAQLVHEAGM
HHCCEEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
ICHAGHGIDYECAAAISKVKHITAINVGHFLVCEAITQGMGNAVRKMKDIITS
EEECCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA