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The map label for this gene is ald1 [H]

Identifier: 88195172

GI number: 88195172

Start: 1409132

End: 1410250

Strand: Reverse

Name: ald1 [H]

Synonym: SAOUHSC_01452

Alternate gene names: 88195172

Gene position: 1410250-1409132 (Counterclockwise)

Preceding gene: 88195173

Following gene: 88195171

Centisome position: 49.98

GC content: 35.3

Gene sequence:

>1119_bases
ATGTTAGTTGCAGTAGTCAAAGAATTAAAACAAGGTGAAGGACGTGTAGCTTGCACACCCGAAAATGTGCGTAAGTTAAC
GGATGCAGGACATAAAGTAATTGTTGAAAAAAATGCTGGCATTGGTTCAGGATTTTCTAACGATATGTATGAAAAAGAAG
GCGCTAAGATCGTAACTCACGAACAAGCATGGGAAGCTGATCTTGTTATCAAAGTAAAAGAACCTCATGAAAGCGAATAT
CAATATTTCAAAAAGAATCAAATTATCTGGGGATTTTTACATCTAGCATCTTCAAAAGAAATAGTAGAAAAAATGCAAGA
AGTTGGTGTAACTGCGATTAGTGGTGAAACCATTATAAAAAATGGAAAAGCAGAATTATTAGCGCCAATGAGTGCTATAG
CAGGTCAACGCTCAGCAATTATGGGAGCTTACTACTCTGAAGCACAACATGGTGGTCAAGGTACTTTAGTGACTGGTGTA
CATGAAAATGTGGATATACCTGGTAGTACATATGTGATTTTCGGTGGTGGAGTAGCAGCAACAAATGCAGCAAATGTTGC
CTTGGGACTAAATGCTAAAGTAATCATTATCGAGTTAAACGATGACCGCATTAAATATCTTGAAGATATGTATGCAGAAA
AAGATGTCACAGTAGTCAAATCAACACCAGAAAATTTAGCAGAACAAATTAAGAAAGCAGATGTATTTATTTCTACAATT
TTAATTTCAGGTGCGAAACCGCCAAAATTGGTTACTCGTGAGATGGTTAAATCAATGAAAAAAGGTTCAGTATTAATCGA
TATAGCTATTGACCAAGGTGGAACTATTGAAACAATTAGACCAACTACAATTTCTGATCCAGTGTATGAAGAAGAAGGTG
TGATTCATTATGGTGTACCAAATCAACCAGGAGCAGTCCCAAGAACTTCAACAATGGCATTAGCACAAGGAAATATTGAT
TATATATTAGAAATTTGTGACAAAGGCTTAGAACAAGCAATTAAAGATAATGAAGCCTTAAGTACTGGTGTAAACATTTA
CCAAGGACAAGTGACAAATCAAGGATTAGCTTCATCACATGACCTAGATTATAAAGAAATATTAAATGTTATCGAATAG

Upstream 100 bases:

>100_bases
TAGATAAAATATGAATAATTAATTAATGGTATTTACATATTCATAACCAAAGGATAAAATAATTGTGAAATTATTCACAA
ATGAAAGAGGAGTGTTGCAA

Downstream 100 bases:

>100_bases
ATAGTAATTTAAATGAAATTGAGTGAAATGAATATTTTAAATATAGCATTATAGTTTGGACTAAAAATTTACAAAACGGA
AGGATGTAATTATTATGACA

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LISGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE

Sequences:

>Translated_372_residues
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LISGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE
>Mature_372_residues
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LISGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=359, Percent_Identity=29.8050139275766, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI122939153, Length=359, Percent_Identity=29.8050139275766, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1787887, Length=352, Percent_Identity=29.2613636363636, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17550456, Length=346, Percent_Identity=29.7687861271676, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 40225; Mature: 40225

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTH
CHHHHHHHHHCCCCCEEECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCCEEEEE
EQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIK
CCCCCCEEEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEECCCCEEE
NGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
TNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHEEHH
LISGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVP
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCC
NQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCCCCCC
DLDYKEILNVIE
CCCHHHHHHHHC
>Mature Secondary Structure
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTH
CHHHHHHHHHCCCCCEEECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCCEEEEE
EQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIK
CCCCCCEEEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEECCCCEEE
NGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
TNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHEEHH
LISGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVP
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCC
NQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCCCCCC
DLDYKEILNVIE
CCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA