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The map label for this gene is ltaA [H]

Identifier: 88194709

GI number: 88194709

Start: 925707

End: 926915

Strand: Reverse

Name: ltaA [H]

Synonym: SAOUHSC_00952

Alternate gene names: 88194709

Gene position: 926915-925707 (Counterclockwise)

Preceding gene: 88194710

Following gene: 88194705

Centisome position: 32.85

GC content: 32.18

Gene sequence:

>1209_bases
ATGGAAAGGTTCCTTTATATGCAAGATTCTTCGTTAAATAATTACGCTAATCATAAAAATTTCATTTTAATGCTTATTAT
CTTATTTTTAATGGAATTTGCGAGAGGCATGTATATCCTAAGCTATATTAATTTCTTGCCAACAGTTACATCCATTGCTG
TAGCAATAACGTCTCTAGCATTTTCAATACATTTTATTGCTGATGCATCTACAAACTTTGTTATAGGATTTTTACTGAAA
AAATTCGGCACAAAAATCGTTTTAACGACTGGATTTATTTTAGCATTTACAAGTTTATTTTTAGTTATTTGGTTTCCAGC
ATCACCTTTTGTAATCATATTTAGTGCTATGATGCTCGGTATTGCAGTTAGTCCTATTTGGGTCATTATGTTATCCAGTG
TTGAAGAAGATAAACGTGGCAAACAAATGGGCTATGTTTATTTTTCATGGTTGTTAGGCCTATTGGTAGGTATGGTTTTT
ATGAATCTACTTATCAAAGTGCACCCAACACGCTTTGCCTTCATGATGTCTTTAGTCGTTTTAATTGCATGGATATTATA
TTATTTTGTCGATGTAAAGTTAACAAATTATAATACTCGTCCAGTTAAAGCTCAATTGAGACAAATTGTTGATGTGACAA
AGCGCCATTTATTGTTGTTCCCTGGTATTCTTTTACAAGGTGCCGCAATTGCTGCCCTAGTTCCTATATTACCAACATAT
GCTACTAAGGTTATTAACGTAAGCACAATTGAATATACTGTTGCAATCATTATTGGTGGTATCGGCTGTGCAGTTTCGAT
GCTATTTTTATCGAAACTAATAGATAACCGCAGCAGAAACTTTATGTATGGTGTTATTCTAAGCGGATTTATTTTATACA
TGATATTAATTTTTACTCTATCTATGATTGTTAATATTCACATCTTGTGGATTATCGCTTTAGCTATCGGTCTAATGTAT
GGCATCTTATTACCAGCATGGAATACCTTTATGGCACGATTTATCAAATCAGATGAACAAGAAGAAACTTGGGGTGTTTT
TAATAGTATCCAAGGATTCGGCTCAATGATAGGGCCATTATTTGGCGGATTAATTACACAATTTACCAACAATTTAAACA
ATACATTTTATTTCTCGGCATTAATCTTTTTAGTCTTAGCTGTATTTTATGGAAGCTACTTTATAGTAAATAGAGAAAAA
GCTAAGTAA

Upstream 100 bases:

>100_bases
ATTAGTACAATGGAACAAGATAAAATTAAGTATGCTACACAGACAATATGTCGAGACTTACTTGATTTAATCGGTCATTC
ATCACAACCACAAGAGATTT

Downstream 100 bases:

>100_bases
GGTTAAAACGTATTTTAAAATAAAGAAAATGGTCATTTTTATTACATTCAATAAAAATGACCATTTTCTTATTAATTCAA
ACATACTACGATTAACAATA

Product: hypothetical protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: Lipoteichoic acid protein A [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLK
KFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVF
MNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTY
ATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHILWIIALAIGLMY
GILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREK
AK

Sequences:

>Translated_402_residues
MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLK
KFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVF
MNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTY
ATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHILWIIALAIGLMY
GILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREK
AK
>Mature_402_residues
MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLK
KFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVF
MNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTY
ATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHILWIIALAIGLMY
GILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREK
AK

Specific function: Probable permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. LtaA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45458; Mature: 45458

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLG
HHHHEEECCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTY
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTL
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SMIVNIHILWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
FGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREKAK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCC
>Mature Secondary Structure
MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLG
HHHHEEECCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTY
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTL
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SMIVNIHILWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
FGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREKAK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA