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The map label for this gene is ptsG [H]

Identifier: 88193967

GI number: 88193967

Start: 166663

End: 168660

Strand: Reverse

Name: ptsG [H]

Synonym: SAOUHSC_00155

Alternate gene names: 88193967

Gene position: 168660-166663 (Counterclockwise)

Preceding gene: 88193972

Following gene: 88193965

Centisome position: 5.98

GC content: 37.74

Gene sequence:

>1998_bases
ATGTTACCTGTTGCGATTTTACCAGCAGCTGGTCTGTTATTAGCTATCGGTACAGCTATGCAAGGTGAATCATTACAACA
CTACTTGCCGTTTATACAAAATGGTGGCGTACAAACTGTCGCTAAATTAATGACAGGTGCTGGTGGTATCATTTTTGATA
ACTTGCCTATGATTTTCGCATTAGGTGTCGCAATCGGATTAGCTGGCGGTGATGGCGTAGCAGCTATCGCAGCATTCGTC
GGTTACATAATCATGAACAAAACAATGGGCGACTTTTTACAAGTTACACCTAAGAATATTGGTGATCCAGCGAGTGGTTA
CGCTAGCATTTTAGGTATCCCAACATTACAAACAGGTGTGTTCGGCGGTATTATAATCGGGGCCCTGGCAGCTTGGTGTT
ATAACAAGTTCTATAACATTAACTTACCATCTTATTTAGGTTTCTTCGCTGGTAAGCGTTTCGTACCTATTATGATGGCT
ACAACATCATTTATTTTAGCATTCCCAATGGCATTAATTTGGCCAACGATTCAATCAGGATTAAATGCATTCAGTACAGG
ATTATTAGATTCAAATACTGGTGTTGCCGTATTCTTATTTGGTTTCATCAAGCGTTTATTAATTCCATTCGGTCTACATC
ACATTTTCCACGCACCGTTCTGGTTCGAGTTTGGTTCATGGAAAAATGCAGCTGGTGAAATTATTCACGGTGACCAACGT
ATCTTTATCGAACAAATTCGTGAAGGCGCACATTTGACAGCTGGTAAATTCATGCAAGGTGAATTCCCTGTTATGATGTT
CGGTTTACCTGCAGCAGCTTTAGCAATTTATCACACAGCTAAACCTGAAAATAAGAAAGTAGTAGCAGGTTTAATGGGTT
CTGCTGCTTTAACATCATTCTTAACTGGTATTACAGAACCATTAGAATTCTCATTCTTATTTGTAGCACCATTATTATTC
TTTATTCACGCAGTACTTGATGGTTTATCATTCTTAACATTGTACTTATTAGATCTTCATCTAGGTTATACATTCTCAGG
TGGTTTCATCGACTACTTCTTACTCGGTATACTACCTAATAAGACACAATGGTGGTTAGTCATTCCTGTAGGTCTTGTAT
ACGCAGTTATTTACTACTTCGTATTCCGATTCTTAATTGTAAAATTAAAATACAAAACACCAGGTCGTGAAGATAAACAA
TCACAAGCGGCTACTGCTTCAGCAACTGAATTACCATATGCAGTATTAGAAGCTATGGGTGGCAAAGCAAACATTAAACA
TTTAGACGCTTGTATCACACGTCTACGTGTTGAAGTTAACGACAAATCTAAAGTTGATGTTCCTGGTTTGAAAGATTTAG
GCGCATCTGGTGTATTAGAAGTCGGCAATAATATGCAAGCAATTTTTGGTCCTAAATCTGACCAAATCAAACATGAAATG
CAACAGATTATGAATGGTCAAGTAGTAGAAAATCCTACTACTATGGAAGACGATAAAGACGAAACTGTTGTTGTTGCAGA
AGATAAATCTGCAACAAGCGAATTGAGCCATATCGTGCATGCACCATTAACTGGTGAAGTAACACCATTATCAGAAGTGC
CTGATCAAGTGTTCAGCGAAAAAATGATGGGTGACGGTATCGCTATCAAACCTTCACAAGGTGAAGTTCGTGCACCATTC
AACGGTAAAGTACAAATGATTTTCCCAACAAAACATGCAATTGGTCTTGTATCAGATAGTGGTTTAGAACTATTAATCCA
CATCGGTTTAGACACTGTTAAATTAAACGGAGAAGGCTTTACTTTACATGTTGAGGAAGGTCAAGAAGTTAAACAAGGTG
ATTTATTAATCAACTTTGATTTAGACTACATCCGCAATCATGCAAAGAGTGATATTACGCCTATTATCGTGACACAAGGA
AACATTACAAACCTTGATTTTAAACAAGGTGAACATGGCAACATTTCATTTGGCGATCAATTATTTGAAGCTAAATAA

Upstream 100 bases:

>100_bases
GTCTTTTTTTATTGAATCTTAAATAATAAATACAACTTTGGAGGTTGGACAAGTGAGGAAGAAACTTTTCGGTCAATTGC
AACGTATTGGTAAAGCGCTA

Downstream 100 bases:

>100_bases
TGCTTACTATAAACAGGTGCGTATACCTTCATAAGGTGACGCGCCTGTTTTTTCTTTGCTATTGTATTTTGCAGCATCAT
TGATAGTTCGCTCTCCCCTT

Product: PTS system glucose-specific protein

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFV
GYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMA
TTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQR
IFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLF
FIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQ
SQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEM
QQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPF
NGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQG
NITNLDFKQGEHGNISFGDQLFEAK

Sequences:

>Translated_665_residues
MLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFV
GYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMA
TTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQR
IFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLF
FIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQ
SQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEM
QQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPF
NGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQG
NITNLDFKQGEHGNISFGDQLFEAK
>Mature_665_residues
MLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFV
GYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMA
TTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQR
IFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLF
FIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQ
SQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEM
QQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPF
NGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQG
NITNLDFKQGEHGNISFGDQLFEAK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=487, Percent_Identity=49.4866529774127, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1786894, Length=655, Percent_Identity=38.6259541984733, Blast_Score=397, Evalue=1e-111,
Organism=Escherichia coli, GI1787908, Length=506, Percent_Identity=37.3517786561265, Blast_Score=315, Evalue=6e-87,
Organism=Escherichia coli, GI1788757, Length=143, Percent_Identity=48.2517482517483, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1790159, Length=123, Percent_Identity=46.3414634146341, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 72057; Mature: 72057

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFA
CCCEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCHHHHH
LGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGV
HHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCHHHHHCCCCHHHHH
FGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEECCHH
IFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSF
HHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHH
LTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCCC
KTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMG
CCCEEEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHCCCHHHCCHHHHHHCC
GKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEM
CCCCHHHHHHHHHHHEEEECCCCCCCCCCHHHCCCCCHHHCCCCCEEEECCCHHHHHHHH
QQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSE
HHHHCCEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
KMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGF
HHCCCCEEEECCCCCEECCCCCEEEEEECCCHHEEEECCCCCEEEEEECCEEEEECCCEE
TLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQ
EEEECCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCCCCCCCH
LFEAK
HHCCC
>Mature Secondary Structure
MLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFA
CCCEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCHHHHH
LGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGV
HHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCHHHHHCCCCHHHHH
FGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEECCHH
IFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSF
HHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHH
LTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCCC
KTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMG
CCCEEEEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHCCCHHHCCHHHHHHCC
GKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEM
CCCCHHHHHHHHHHHEEEECCCCCCCCCCHHHCCCCCHHHCCCCCEEEECCCHHHHHHHH
QQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSE
HHHHCCEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
KMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGF
HHCCCCEEEECCCCCEECCCCCEEEEEECCCHHEEEECCCCCEEEEEECCEEEEECCCEE
TLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQ
EEEECCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCCCCCCCH
LFEAK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA