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The map label for this gene is spa

Identifier: 88193885

GI number: 88193885

Start: 73429

End: 74979

Strand: Reverse

Name: spa

Synonym: SAOUHSC_00069

Alternate gene names: 88193885

Gene position: 74979-73429 (Counterclockwise)

Preceding gene: 88193886

Following gene: 88193881

Centisome position: 2.66

GC content: 38.17

Gene sequence:

>1551_bases
TTGAAAAAGAAAAACATTTATTCAATTCGTAAACTAGGTGTAGGTATTGCATCTGTAACTTTAGGTACATTACTTATATC
TGGTGGCGTAACACCTGCTGCAAATGCTGCGCAACACGATGAAGCTCAACAAAATGCTTTTTATCAAGTCTTAAATATGC
CTAACTTAAATGCTGATCAACGCAATGGTTTTATCCAAAGCCTTAAAGATGATCCAAGCCAAAGTGCTAACGTTTTAGGT
GAAGCTCAAAAACTTAATGACTCTCAAGCTCCAAAAGCTGATGCGCAACAAAATAACTTCAACAAAGATCAACAAAGCGC
CTTCTATGAAATCTTGAACATGCCTAACTTAAACGAAGCGCAACGTAACGGCTTCATTCAAAGTCTTAAAGACGACCCAA
GCCAAAGCACTAACGTTTTAGGTGAAGCTAAAAAATTAAACGAATCTCAAGCACCGAAAGCTGATAACAATTTCAACAAA
GAACAACAAAATGCTTTCTATGAAATCTTGAATATGCCTAACTTAAACGAAGAACAACGCAATGGTTTCATCCAAAGCTT
AAAAGATGACCCAAGCCAAAGTGCTAACCTATTGTCAGAAGCTAAAAAGTTAAATGAATCTCAAGCACCGAAAGCGGATA
ACAAATTCAACAAAGAACAACAAAATGCTTTCTATGAAATCTTACATTTACCTAACTTAAACGAAGAACAACGCAATGGT
TTCATCCAAAGCCTAAAAGATGACCCAAGCCAAAGCGCTAACCTTTTAGCAGAAGCTAAAAAGCTAAATGATGCTCAAGC
ACCAAAAGCTGACAACAAATTCAACAAAGAACAACAAAATGCTTTCTATGAAATTTTACATTTACCTAACTTAACTGAAG
AACAACGTAACGGCTTCATCCAAAGCCTTAAAGACGATCCTTCAGTGAGCAAAGAAATTTTAGCAGAAGCTAAAAAGCTA
AACGATGCTCAAGCACCAAAAGAGGAAGACAATAACAAGCCTGGCAAAGAAGACAATAACAAGCCTGGCAAAGAAGACAA
CAACAAGCCTGGTAAAGAAGACAACAACAAGCCTGGTAAAGAAGACAACAACAAGCCTGGCAAAGAAGACGGCAACAAGC
CTGGTAAAGAAGACAACAAAAAACCTGGTAAAGAAGATGGCAACAAGCCTGGTAAAGAAGACAACAAAAAACCTGGTAAA
GAAGACGGCAACAAGCCTGGCAAAGAAGATGGCAACAAACCTGGTAAAGAAGATGGTAACGGAGTACATGTCGTTAAACC
TGGTGATACAGTAAATGACATTGCAAAAGCAAACGGCACTACTGCTGACAAAATTGCTGCAGATAACAAATTAGCTGATA
AAAACATGATCAAACCTGGTCAAGAACTTGTTGTTGATAAGAAGCAACCAGCAAACCATGCAGATGCTAACAAAGCTCAA
GCATTACCAGAAACTGGTGAAGAAAATCCATTCATCGGTACAACTGTATTTGGTGGATTATCATTAGCCTTAGGTGCAGC
GTTATTAGCTGGACGTCGTCGCGAACTATAA

Upstream 100 bases:

>100_bases
AACTTACCTTTAAATTTAATTATAAATATAGATTTTAGTATTGCAATACATAATTCGTTATATTATGATGACTTTACAAA
TACATACAGGGGGTATTAAT

Downstream 100 bases:

>100_bases
AAACAAACAATACACAACGATAGATATCATTTTATCCAAACCAATTTTAACTTATATACGTTGATTAACACATTCTTATT
TGAAATGATAAGAATCATCT

Product: protein A

Products: NA

Alternate protein names: IgG-binding protein A; Staphylococcal protein A

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLG
EAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNK
EQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNG
FIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKL
NDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGK
EDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQ
ALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL

Sequences:

>Translated_516_residues
MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLG
EAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNK
EQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNG
FIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKL
NDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGK
EDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQ
ALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL
>Mature_516_residues
MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLG
EAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNK
EQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNG
FIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKL
NDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGK
EDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQ
ALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat

Homologues:

Organism=Homo sapiens, GI118722349, Length=99, Percent_Identity=34.3434343434343, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPA_STAA8 (P02976)

Other databases:

- EMBL:   J01786
- EMBL:   CP000253
- EMBL:   V01287
- PIR:   A58531
- RefSeq:   YP_498670.1
- PDB:   1DEE
- PDBsum:   1DEE
- ProteinModelPortal:   P02976
- MINT:   MINT-1206155
- STRING:   P02976
- EnsemblBacteria:   EBSTAT00000029248
- GeneID:   3919448
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_00069
- eggNOG:   NOG135867
- GeneTree:   EBGT00050000023692
- HOGENOM:   HBG692912
- OMA:   KHAREAG
- ProtClustDB:   CLSK884404
- BioCyc:   SAUR93061:SAOUHSC_00069-MONOMER
- GO:   GO:0016020
- GO:   GO:0009405
- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR009063
- InterPro:   IPR019931
- InterPro:   IPR005038
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003132
- InterPro:   IPR001899
- SMART:   SM00257
- TIGRFAMs:   TIGR01167
- TIGRFAMs:   TIGR01168

Pfam domain/function: PF02216 B; PF00746 Gram_pos_anchor; PF01476 LysM; PF03373 Octapeptide; PF04650 YSIRK_signal; SSF46997 Bac_Ig/alb_bind

EC number: NA

Molecular weight: Translated: 56438; Mature: 56438

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQ
CCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
RNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEA
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCHH
QRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYEILNMPNLNEEQR
HHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
NGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNG
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
FIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFI
HHHHHHCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
QSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGK
HHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQ
EEEEECCCCHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCHHHEECCCCCCCCCCCHHHH
ALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQ
CCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
RNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEA
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCHH
QRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYEILNMPNLNEEQR
HHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
NGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNG
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
FIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFI
HHHHHHCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
QSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGK
HHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQ
EEEEECCCCHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCHHHEECCCCCCCCCCCHHHH
ALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6319407; 6338496