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The map label for this gene is argD

Identifier: 87201153

GI number: 87201153

Start: 3351346

End: 3352539

Strand: Reverse

Name: argD

Synonym: Saro_3141

Alternate gene names: 87201153

Gene position: 3352539-3351346 (Counterclockwise)

Preceding gene: 87201154

Following gene: 87201152

Centisome position: 94.13

GC content: 64.57

Gene sequence:

>1194_bases
ATGTCGATCACTCCGCTGATGCCCGTGTATCCCCGGTGCGGCGTGCGTCCTGTGCGAGGCGAGCATTGCCACCTGATCTC
CGAGGACGGCACCCGCTACCTTGATTTCGCAAGCGGCATCGCGGTGAATCTGCTCGGCCATTCGAACGAACACCTGATCG
GCGCGATCCAGAAGCAGGCGGCGACGCTCATGCACGTGTCGAATCTCTACGGGAGCCCGCAGGGCGAGCATCTGGCCCAG
CGCCTGGTCGACCTGACCTTCGCCGACACGGTGTTCTTCACCAATTCCGGCGCGGAGGCGGTGGAATGCGCGATCAAGAC
CGCGCGCGCATATCACTCGTCGGTGGGCAATGACCACAAGTACGAGCTGATCACCTTCAAGAACGCCTTCCACGGCCGCA
CGATGGCCACGATCAGCGCCTCCAAACAGGAGAAGATGCACAAGGGCTTCCTGCCGCTGCTGGAAGGCTTCAAGTACGTC
GACTTCGACGATCTGGAAGGTGCGAAGGCCGCGATGGGCCCAAACACGGCGGGCTTCCTCGTCGAGCCGATCCAGGGCGA
AGGCGGCATCCGCGATGCCTCTGACGAATTTCTCAAGGGCCTTCGCGCGCTTTGCGACGAACATGACCTCGTGCTGATCT
TCGATGAAGTGCAGTGCGGCGTGGCGCGCACCGGCACGCTCTATGCCTACGAGCAGTACGGCATCACGCCCGACGTGATG
GCGACCGCCAAGGGAATCGGCGGCGGCTTCCCGATCGGCGCCTGCCTTGCCACCGAAAAGGCTGCGCGCGGCATGGTCGC
CGGCACCCACGGCAGCACTTATGGCGGTAACCCGCTGGCCATGGCTGCGGGCGAGGCCGTGCTCGACGTCGTGGCGAACG
AGGAATTTCTCGGCGAAGTGCGGGCCAAGGGCGAACGCCTGCGCGGGCGGATCGAGCAGTTCATCGGCAACTACCCCGAT
CTGTTCATCGGCGTGCGCGGGCGCGGCCTGATGCTCGGCCTGATGATGAAGGTGGAGCCGCGTCCGTTCGTGGCGCACAT
GCGCGACAACCATCAGTTGCTCACTGTCTCGGCCGGTGACAACACCGTGCGCGTGATCCCGCCGCTGGTCATCGACGACA
GCCACATCGACGAATTCATGGAGCGGCTTTCGGCCGCTGCCGCAAGCTATGCGCCGGAGGCGCCGGTCACGTGA

Upstream 100 bases:

>100_bases
CGGGGCCGCCATTTGTCGTTTGCGTTTCCCGAGCTACGCCGGAAAAGGATCAAGGCCGGCGACCCGTTGTTTTCGTTCGT
GAATGAACAGGAGAATGCCA

Downstream 100 bases:

>100_bases
GCCAGGCCCTCAAGCACTTCCTGAACCTGACGGATGCGGGCGGCGATGCCATCGCCGCGATGCTGAACGACGCGCTCGAC
CGCAAGTCCGCGCGCGCTGG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSITPLMPVYPRCGVRPVRGEHCHLISEDGTRYLDFASGIAVNLLGHSNEHLIGAIQKQAATLMHVSNLYGSPQGEHLAQ
RLVDLTFADTVFFTNSGAEAVECAIKTARAYHSSVGNDHKYELITFKNAFHGRTMATISASKQEKMHKGFLPLLEGFKYV
DFDDLEGAKAAMGPNTAGFLVEPIQGEGGIRDASDEFLKGLRALCDEHDLVLIFDEVQCGVARTGTLYAYEQYGITPDVM
ATAKGIGGGFPIGACLATEKAARGMVAGTHGSTYGGNPLAMAAGEAVLDVVANEEFLGEVRAKGERLRGRIEQFIGNYPD
LFIGVRGRGLMLGLMMKVEPRPFVAHMRDNHQLLTVSAGDNTVRVIPPLVIDDSHIDEFMERLSAAAASYAPEAPVT

Sequences:

>Translated_397_residues
MSITPLMPVYPRCGVRPVRGEHCHLISEDGTRYLDFASGIAVNLLGHSNEHLIGAIQKQAATLMHVSNLYGSPQGEHLAQ
RLVDLTFADTVFFTNSGAEAVECAIKTARAYHSSVGNDHKYELITFKNAFHGRTMATISASKQEKMHKGFLPLLEGFKYV
DFDDLEGAKAAMGPNTAGFLVEPIQGEGGIRDASDEFLKGLRALCDEHDLVLIFDEVQCGVARTGTLYAYEQYGITPDVM
ATAKGIGGGFPIGACLATEKAARGMVAGTHGSTYGGNPLAMAAGEAVLDVVANEEFLGEVRAKGERLRGRIEQFIGNYPD
LFIGVRGRGLMLGLMMKVEPRPFVAHMRDNHQLLTVSAGDNTVRVIPPLVIDDSHIDEFMERLSAAAASYAPEAPVT
>Mature_396_residues
SITPLMPVYPRCGVRPVRGEHCHLISEDGTRYLDFASGIAVNLLGHSNEHLIGAIQKQAATLMHVSNLYGSPQGEHLAQR
LVDLTFADTVFFTNSGAEAVECAIKTARAYHSSVGNDHKYELITFKNAFHGRTMATISASKQEKMHKGFLPLLEGFKYVD
FDDLEGAKAAMGPNTAGFLVEPIQGEGGIRDASDEFLKGLRALCDEHDLVLIFDEVQCGVARTGTLYAYEQYGITPDVMA
TAKGIGGGFPIGACLATEKAARGMVAGTHGSTYGGNPLAMAAGEAVLDVVANEEFLGEVRAKGERLRGRIEQFIGNYPDL
FIGVRGRGLMLGLMMKVEPRPFVAHMRDNHQLLTVSAGDNTVRVIPPLVIDDSHIDEFMERLSAAAASYAPEAPVT

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=382, Percent_Identity=32.4607329842932, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI284507298, Length=305, Percent_Identity=34.4262295081967, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI13994255, Length=420, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI188536080, Length=433, Percent_Identity=24.4803695150115, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38679950, Length=433, Percent_Identity=24.4803695150115, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38679946, Length=433, Percent_Identity=24.4803695150115, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI37574042, Length=411, Percent_Identity=24.5742092457421, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI226442705, Length=411, Percent_Identity=24.5742092457421, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=24.5192307692308, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI226442709, Length=331, Percent_Identity=25.0755287009063, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=43.2225063938619, Blast_Score=318, Evalue=3e-88,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=41.7948717948718, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI145693181, Length=361, Percent_Identity=34.3490304709141, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.1658291457286, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=32.8395061728395, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786991, Length=336, Percent_Identity=32.4404761904762, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786349, Length=293, Percent_Identity=31.3993174061433, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=382, Percent_Identity=31.151832460733, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=286, Percent_Identity=30.7692307692308, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564660, Length=448, Percent_Identity=26.5625, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=418, Percent_Identity=27.0334928229665, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=335, Percent_Identity=25.0746268656716, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=154, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=388, Percent_Identity=38.1443298969072, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6323470, Length=389, Percent_Identity=29.5629820051414, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=398, Percent_Identity=26.1306532663317, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=426, Percent_Identity=25.1173708920188, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21357415, Length=370, Percent_Identity=31.8918918918919, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28574759, Length=430, Percent_Identity=29.0697674418605, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI161085790, Length=432, Percent_Identity=28.7037037037037, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21356575, Length=409, Percent_Identity=26.161369193154, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281366494, Length=292, Percent_Identity=26.7123287671233, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667139, Length=292, Percent_Identity=26.7123287671233, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667143, Length=292, Percent_Identity=26.7123287671233, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42811; Mature: 42680

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITPLMPVYPRCGVRPVRGEHCHLISEDGTRYLDFASGIAVNLLGHSNEHLIGAIQKQA
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEHHCCCEEEEECCCCCHHHHHHHHHH
ATLMHVSNLYGSPQGEHLAQRLVDLTFADTVFFTNSGAEAVECAIKTARAYHSSVGNDHK
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCE
YELITFKNAFHGRTMATISASKQEKMHKGFLPLLEGFKYVDFDDLEGAKAAMGPNTAGFL
EEEEEECCCCCCCEEEEEECHHHHHHHHCHHHHHHCCCCCCCCCCCCCCHHCCCCCCCEE
VEPIQGEGGIRDASDEFLKGLRALCDEHDLVLIFDEVQCGVARTGTLYAYEQYGITPDVM
EEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHH
ATAKGIGGGFPIGACLATEKAARGMVAGTHGSTYGGNPLAMAAGEAVLDVVANEEFLGEV
HHHCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHH
RAKGERLRGRIEQFIGNYPDLFIGVRGRGLMLGLMMKVEPRPFVAHMRDNHQLLTVSAGD
HHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEECCCCEEEEECCCCEEEEEECCC
NTVRVIPPLVIDDSHIDEFMERLSAAAASYAPEAPVT
CEEEEECCEEECCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SITPLMPVYPRCGVRPVRGEHCHLISEDGTRYLDFASGIAVNLLGHSNEHLIGAIQKQA
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEHHCCCEEEEECCCCCHHHHHHHHHH
ATLMHVSNLYGSPQGEHLAQRLVDLTFADTVFFTNSGAEAVECAIKTARAYHSSVGNDHK
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCE
YELITFKNAFHGRTMATISASKQEKMHKGFLPLLEGFKYVDFDDLEGAKAAMGPNTAGFL
EEEEEECCCCCCCEEEEEECHHHHHHHHCHHHHHHCCCCCCCCCCCCCCHHCCCCCCCEE
VEPIQGEGGIRDASDEFLKGLRALCDEHDLVLIFDEVQCGVARTGTLYAYEQYGITPDVM
EEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHH
ATAKGIGGGFPIGACLATEKAARGMVAGTHGSTYGGNPLAMAAGEAVLDVVANEEFLGEV
HHHCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHH
RAKGERLRGRIEQFIGNYPDLFIGVRGRGLMLGLMMKVEPRPFVAHMRDNHQLLTVSAGD
HHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEECCCCEEEEECCCCEEEEEECCC
NTVRVIPPLVIDDSHIDEFMERLSAAAASYAPEAPVT
CEEEEECCEEECCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]