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The map label for this gene is mcpA [H]

Identifier: 87201060

GI number: 87201060

Start: 3263390

End: 3265195

Strand: Reverse

Name: mcpA [H]

Synonym: Saro_3048

Alternate gene names: 87201060

Gene position: 3265195-3263390 (Counterclockwise)

Preceding gene: 87201066

Following gene: 87201059

Centisome position: 91.68

GC content: 67.77

Gene sequence:

>1806_bases
ATGCGAAAAATGCGGCACTTGCATGCCGGAAGATCATACCCGGAGCGGAGGCAGCCGATGCTGCAAGGGCAGTCGATCAC
CAGGAAAGTCATGGCCGGATGCCTGATCCTTGGCCTCGGCGCCATGGCGTCCACGGGCCTCGGCCTGGCCGGGACCGTGC
GGCTGGAGGCGGCTATGGAGAAGCTCAATGCCGCGACCGCCCTGCTGCGTGCGCACATGGAGGCCGACATGGGGCACGAC
GCAATCCGGAGCGAAGTGGTTAGCATCGTCGCATCCAGGCAGACGGCGGCCATCGACGGGCTTGCGGCGGGTCGCGAACT
GGCCGACAGGCTGGTCGAGTTCGAGAAGAACATGGAACCGACCGCCAAGGTCGAGGATGCGCCGGAAGTGAGCGCCGCGC
GCGCGGCAGCCGACCCTGCGTTCAGGGCCTATGTGGCGATCGGCCGCGAAGTTTCGGCTGCCGCAGAACGCGGCGCTGTG
CCGGGCGATGCCGAACTGCAGAGGTTCCAGCATCTGTTCACGCAACTTGAAGCGGATATGTCGAAGATCTCCGACGCGGT
CGAGGCGCATTCGAGCGAGACGGTCGCAGAGGCAAGCTCTGCCGCCGCTCAGGCGCGCGTGCTTGGCATCGGCAGCCTGT
TCGTACTGCTTGGCATTCTCGCCGCGGTGGTCCGGTTTGCCCGCCGCGATCTCGTCGACCCGGTCATCGCCATTGCCGGA
AGGGTCCGGGCCATGTCCGACGGGCGGCTCGACGTGGAAATGGACGGGGCCCGACGGGCCGACGAGATTGGCGACCTTGC
GCGCTCGGTCGTGGCCCTGCGCGACAACCTCGCCCAGGCGCGGGCCGAGACCGCCGGGCAGGCGGAAGCGATCGTGGCTT
CGATCGGGGCTGGGCTGAGCCAGCTTGCTTCCGGCAACGTCGGATATCGAATTCGCGAGACGCTCGCCGGTCCGTTCCAG
AAGCTGCGCGACGATTTCAACCGCGCCATGGACGAGATGGCTTCCGCCCTGTGCGCGGTGCAGACGGCTACCGCGACGCT
CGATGCGGTCGCGCGCGATATCGGCGGTGCGGCGGGGGACCTGTCCAACCGCAACGCCAACCAGGCCGCCAGCCTGCAGG
AAACCGCGGCCGCCATCGCCAGCCTTGCCCAGCGCGTCGCTGGATCGTCCGAGGCCGTCACGGCCGCACGGGCAGCCGTC
GGCCACGTCGGCAGCGAGGTCAGCCGGGGCGGCGGCGTCATCGACGACGCGGAGCAGGCAATGGATCGGATAGAGATCGC
CTCACAGGAAATCGGCACGATCGTGGGCGTCATCGACGGCATCGCCTTCCAGACCAACCTGCTCGCCCTGAACGCCGGGG
TGGAGGCCGCGCGCGCGGGTGAATCGGGCAAGGGCTTTGCCGTTGTCGCCAGCGAGGTTCGCGCGCTTGCCCAGCGCAGC
GCCGACGCGGCGCGGGAGATCAAGCAACTTATCGCCAACTCCTCGTCCGAGATCGGTGACGGTGTTCGGCTGGTGCGCGA
TGCCGGCAGCAGCTTGCGCGCGATCAGCGCGCAGATGGACGAGATCAACCGCGTGATGGAGGTCGTGGAGGCGGGCGCCA
GCGACCAGGACGTTTCGCTGCGCTCCATCGACGAGACGTCGCGCCAGATGGAACAGATAACCCAGAGCAACAGCGCGGTC
GCGGAACAGGTCGGCAATGCGAGCCATGCCGTCGTCTCTGCGATCGAGGACGTGCTGCGGCAGTTGCAGCGTTTCGAGAT
CGGTGAGGCCCGGCGCCCTGCACAAATCCAGGCGCTTGCCGCATGA

Upstream 100 bases:

>100_bases
GAGGCAAGGCGGCGCGCATGGATAAAGCCGATCCAGTCCCCCAAGTGGCATTACCTAAGGCCGTCCTTGCGCCAATTTCA
CCGATGCCAGGGCACAGGGG

Downstream 100 bases:

>100_bases
TCGGGCGTCGGACATCGCATATCGGCCTTGCGGCACTCGCACTCGCGCTTGCGCTTGCGCTTCCGGCCGCCCCGGCCTTC
GCCGAGGAGGAGGGACCGAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MRKMRHLHAGRSYPERRQPMLQGQSITRKVMAGCLILGLGAMASTGLGLAGTVRLEAAMEKLNAATALLRAHMEADMGHD
AIRSEVVSIVASRQTAAIDGLAAGRELADRLVEFEKNMEPTAKVEDAPEVSAARAAADPAFRAYVAIGREVSAAAERGAV
PGDAELQRFQHLFTQLEADMSKISDAVEAHSSETVAEASSAAAQARVLGIGSLFVLLGILAAVVRFARRDLVDPVIAIAG
RVRAMSDGRLDVEMDGARRADEIGDLARSVVALRDNLAQARAETAGQAEAIVASIGAGLSQLASGNVGYRIRETLAGPFQ
KLRDDFNRAMDEMASALCAVQTATATLDAVARDIGGAAGDLSNRNANQAASLQETAAAIASLAQRVAGSSEAVTAARAAV
GHVGSEVSRGGGVIDDAEQAMDRIEIASQEIGTIVGVIDGIAFQTNLLALNAGVEAARAGESGKGFAVVASEVRALAQRS
ADAAREIKQLIANSSSEIGDGVRLVRDAGSSLRAISAQMDEINRVMEVVEAGASDQDVSLRSIDETSRQMEQITQSNSAV
AEQVGNASHAVVSAIEDVLRQLQRFEIGEARRPAQIQALAA

Sequences:

>Translated_601_residues
MRKMRHLHAGRSYPERRQPMLQGQSITRKVMAGCLILGLGAMASTGLGLAGTVRLEAAMEKLNAATALLRAHMEADMGHD
AIRSEVVSIVASRQTAAIDGLAAGRELADRLVEFEKNMEPTAKVEDAPEVSAARAAADPAFRAYVAIGREVSAAAERGAV
PGDAELQRFQHLFTQLEADMSKISDAVEAHSSETVAEASSAAAQARVLGIGSLFVLLGILAAVVRFARRDLVDPVIAIAG
RVRAMSDGRLDVEMDGARRADEIGDLARSVVALRDNLAQARAETAGQAEAIVASIGAGLSQLASGNVGYRIRETLAGPFQ
KLRDDFNRAMDEMASALCAVQTATATLDAVARDIGGAAGDLSNRNANQAASLQETAAAIASLAQRVAGSSEAVTAARAAV
GHVGSEVSRGGGVIDDAEQAMDRIEIASQEIGTIVGVIDGIAFQTNLLALNAGVEAARAGESGKGFAVVASEVRALAQRS
ADAAREIKQLIANSSSEIGDGVRLVRDAGSSLRAISAQMDEINRVMEVVEAGASDQDVSLRSIDETSRQMEQITQSNSAV
AEQVGNASHAVVSAIEDVLRQLQRFEIGEARRPAQIQALAA
>Mature_601_residues
MRKMRHLHAGRSYPERRQPMLQGQSITRKVMAGCLILGLGAMASTGLGLAGTVRLEAAMEKLNAATALLRAHMEADMGHD
AIRSEVVSIVASRQTAAIDGLAAGRELADRLVEFEKNMEPTAKVEDAPEVSAARAAADPAFRAYVAIGREVSAAAERGAV
PGDAELQRFQHLFTQLEADMSKISDAVEAHSSETVAEASSAAAQARVLGIGSLFVLLGILAAVVRFARRDLVDPVIAIAG
RVRAMSDGRLDVEMDGARRADEIGDLARSVVALRDNLAQARAETAGQAEAIVASIGAGLSQLASGNVGYRIRETLAGPFQ
KLRDDFNRAMDEMASALCAVQTATATLDAVARDIGGAAGDLSNRNANQAASLQETAAAIASLAQRVAGSSEAVTAARAAV
GHVGSEVSRGGGVIDDAEQAMDRIEIASQEIGTIVGVIDGIAFQTNLLALNAGVEAARAGESGKGFAVVASEVRALAQRS
ADAAREIKQLIANSSSEIGDGVRLVRDAGSSLRAISAQMDEINRVMEVVEAGASDQDVSLRSIDETSRQMEQITQSNSAV
AEQVGNASHAVVSAIEDVLRQLQRFEIGEARRPAQIQALAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=210, Percent_Identity=46.1904761904762, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788194, Length=211, Percent_Identity=40.7582938388626, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1788195, Length=212, Percent_Identity=42.4528301886792, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1787690, Length=228, Percent_Identity=38.1578947368421, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1789453, Length=201, Percent_Identity=40.2985074626866, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62679; Mature: 62679

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKMRHLHAGRSYPERRQPMLQGQSITRKVMAGCLILGLGAMASTGLGLAGTVRLEAAME
CCCHHHHHCCCCCCHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KLNAATALLRAHMEADMGHDAIRSEVVSIVASRQTAAIDGLAAGRELADRLVEFEKNMEP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TAKVEDAPEVSAARAAADPAFRAYVAIGREVSAAAERGAVPGDAELQRFQHLFTQLEADM
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SKISDAVEAHSSETVAEASSAAAQARVLGIGSLFVLLGILAAVVRFARRDLVDPVIAIAG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVRAMSDGRLDVEMDGARRADEIGDLARSVVALRDNLAQARAETAGQAEAIVASIGAGLS
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLASGNVGYRIRETLAGPFQKLRDDFNRAMDEMASALCAVQTATATLDAVARDIGGAAGD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LSNRNANQAASLQETAAAIASLAQRVAGSSEAVTAARAAVGHVGSEVSRGGGVIDDAEQA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MDRIEIASQEIGTIVGVIDGIAFQTNLLALNAGVEAARAGESGKGFAVVASEVRALAQRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
ADAAREIKQLIANSSSEIGDGVRLVRDAGSSLRAISAQMDEINRVMEVVEAGASDQDVSL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
RSIDETSRQMEQITQSNSAVAEQVGNASHAVVSAIEDVLRQLQRFEIGEARRPAQIQALA
HHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCC
A
C
>Mature Secondary Structure
MRKMRHLHAGRSYPERRQPMLQGQSITRKVMAGCLILGLGAMASTGLGLAGTVRLEAAME
CCCHHHHHCCCCCCHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KLNAATALLRAHMEADMGHDAIRSEVVSIVASRQTAAIDGLAAGRELADRLVEFEKNMEP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TAKVEDAPEVSAARAAADPAFRAYVAIGREVSAAAERGAVPGDAELQRFQHLFTQLEADM
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SKISDAVEAHSSETVAEASSAAAQARVLGIGSLFVLLGILAAVVRFARRDLVDPVIAIAG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVRAMSDGRLDVEMDGARRADEIGDLARSVVALRDNLAQARAETAGQAEAIVASIGAGLS
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLASGNVGYRIRETLAGPFQKLRDDFNRAMDEMASALCAVQTATATLDAVARDIGGAAGD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LSNRNANQAASLQETAAAIASLAQRVAGSSEAVTAARAAVGHVGSEVSRGGGVIDDAEQA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MDRIEIASQEIGTIVGVIDGIAFQTNLLALNAGVEAARAGESGKGFAVVASEVRALAQRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
ADAAREIKQLIANSSSEIGDGVRLVRDAGSSLRAISAQMDEINRVMEVVEAGASDQDVSL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
RSIDETSRQMEQITQSNSAVAEQVGNASHAVVSAIEDVLRQLQRFEIGEARRPAQIQALA
HHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]