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The map label for this gene is gph [H]

Identifier: 87200852

GI number: 87200852

Start: 3065219

End: 3065875

Strand: Direct

Name: gph [H]

Synonym: Saro_2839

Alternate gene names: 87200852

Gene position: 3065219-3065875 (Clockwise)

Preceding gene: 87200851

Following gene: 87200853

Centisome position: 86.06

GC content: 67.73

Gene sequence:

>657_bases
ATGAGACTGGCGATTTTCGATTGCGACGGCACGCTGGTCGACAGCCAGGCCGACATCTGCGCGGCGATGGACGCGGCGTT
TGCCGCAGCCGGGCTTGTCCCGCCCGAACGCCACGCGACGCGACGGGTGGTCGGGCTTTCGCTGCACGAGGCAATGCGCC
AGCTTCACCCCGCAGGCGCGCATGAGGACCATGCCAGCCTGACCGAGCTGTACAAGGATGCCTTCCGCGCGCGCAGGGCG
GCGGGCGCCGTGGCCGAGCCGCTCTATGAAGGCATCGCTGGACTGGTAGAGCAACTGGCGGCCGAGGGCTGGCAGCTTGC
CGTGGCGACGGGCAAGTCGGACCGGGGACTGGCGCATTGTCTTGCGACGCATGGCCTGACCCGCCACTTCGTGTCGTTGC
AGACGGCCGACCGGCATCCTTCGAAACCCGACCCTTCGATGATCGAACAATGCATCGCGGACGCGGGCGCGGACCGGCAT
CGCACGGCGATGATCGGCGACACCGTCTACGACATCGTCATGGCCCGCAACGCAGGGGTGCGCGGCATCGGGGTCGACTG
GGGCTACCACGAGACCGAAGAACTGTTCGAGGCGGGCGCCGAAGCGGTGGCGACGAGCATTGCCGAACTGCGCGCGCTGC
TGGGAGCCATCAAATGA

Upstream 100 bases:

>100_bases
GGCGCGGACGAGCGCGCCCGCGTCGCGGCGGGGCTCGAGGCCGAAGGTTCGCCGGCGATTGCCGAACTGATGCGGAGGCT
GGTGCCGTGAGGACCCTGCG

Downstream 100 bases:

>100_bases
GCGATCCGGCTCAGGATTCGGCCCGGGATCAGGCCCAGGATCAGGCCCAGGATCAGGCAATGCGGCGATTCTTCCTGCTG
CAGGCGGTGCGCGCTTCGGG

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRLAIFDCDGTLVDSQADICAAMDAAFAAAGLVPPERHATRRVVGLSLHEAMRQLHPAGAHEDHASLTELYKDAFRARRA
AGAVAEPLYEGIAGLVEQLAAEGWQLAVATGKSDRGLAHCLATHGLTRHFVSLQTADRHPSKPDPSMIEQCIADAGADRH
RTAMIGDTVYDIVMARNAGVRGIGVDWGYHETEELFEAGAEAVATSIAELRALLGAIK

Sequences:

>Translated_218_residues
MRLAIFDCDGTLVDSQADICAAMDAAFAAAGLVPPERHATRRVVGLSLHEAMRQLHPAGAHEDHASLTELYKDAFRARRA
AGAVAEPLYEGIAGLVEQLAAEGWQLAVATGKSDRGLAHCLATHGLTRHFVSLQTADRHPSKPDPSMIEQCIADAGADRH
RTAMIGDTVYDIVMARNAGVRGIGVDWGYHETEELFEAGAEAVATSIAELRALLGAIK
>Mature_218_residues
MRLAIFDCDGTLVDSQADICAAMDAAFAAAGLVPPERHATRRVVGLSLHEAMRQLHPAGAHEDHASLTELYKDAFRARRA
AGAVAEPLYEGIAGLVEQLAAEGWQLAVATGKSDRGLAHCLATHGLTRHFVSLQTADRHPSKPDPSMIEQCIADAGADRH
RTAMIGDTVYDIVMARNAGVRGIGVDWGYHETEELFEAGAEAVATSIAELRALLGAIK

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23215; Mature: 23215

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAIFDCDGTLVDSQADICAAMDAAFAAAGLVPPERHATRRVVGLSLHEAMRQLHPAGA
CEEEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
HEDHASLTELYKDAFRARRAAGAVAEPLYEGIAGLVEQLAAEGWQLAVATGKSDRGLAHC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHH
LATHGLTRHFVSLQTADRHPSKPDPSMIEQCIADAGADRHRTAMIGDTVYDIVMARNAGV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
RGIGVDWGYHETEELFEAGAEAVATSIAELRALLGAIK
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLAIFDCDGTLVDSQADICAAMDAAFAAAGLVPPERHATRRVVGLSLHEAMRQLHPAGA
CEEEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
HEDHASLTELYKDAFRARRAAGAVAEPLYEGIAGLVEQLAAEGWQLAVATGKSDRGLAHC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHH
LATHGLTRHFVSLQTADRHPSKPDPSMIEQCIADAGADRHRTAMIGDTVYDIVMARNAGV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
RGIGVDWGYHETEELFEAGAEAVATSIAELRALLGAIK
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]