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The map label for this gene is 87200800

Identifier: 87200800

GI number: 87200800

Start: 3007453

End: 3008133

Strand: Direct

Name: 87200800

Synonym: Saro_2787

Alternate gene names: NA

Gene position: 3007453-3008133 (Clockwise)

Preceding gene: 87200799

Following gene: 87200801

Centisome position: 84.44

GC content: 68.14

Gene sequence:

>681_bases
ATGAAGCTCCTGCCGCTCATCGTCATCCGTCCCGAGCCCGGCAATGCCGCAACCATTGCCGCCGCGCGCGAACGGGGCCT
TCATGCGATCGGCTACCCGCTCTTCCGGATCGAGCCGACACGGTGGAGCGTTGCCGAAGGGCGGTTCGAGGCGATCCTGG
CGGGAAGCGCCAACATCTTCCGGCACGGCGGGCCGCAACTCGACGCACTGAAGCATCTCCCCGTCATCGCGGTGGGCGAA
GCGACGGCCTCGGCCGCCCGCGCGGCAGGCTTCACCGTTGTCCGAACCGGCGAAGGCGGCCTGCAACCGGTGGTGGAGAC
GCTTGCCCCCGGCACCTATCTGCGGCTCGCGGGCGAAGACAGGGTCACGCTCGCCCCGCCGCCGGGCGTGCGAATCGAGA
CGGCGGTCGTCTATGCGGCCCGCCCCGTCCCGCTTCCGGACGAGCTGGTGGCGGTACTGGCGCGTCCAGCGGTCGTCCTG
CTGCATTCCGGCGCAGCCGCGAAGCATTTCCGTCAGCAGTGTGAACGCACTGGAATTACTCGGGAAAGCCTCTATCTAGC
GTGCCTCGCCCCGCGCATCGCCGCACTTGCGGGCGATGGTTGGGGCGATCTGCGCATCGCTGACTCAAGAACGGACTCCG
ATCTGCTGGAACTAGGCCGGCGAATGTGCCAGACCATGTGA

Upstream 100 bases:

>100_bases
AGACCTTCGCGGCGGGCGACGATGCAGGCCCCGCCCATCTCGCCCATCGCCTCCTAGGCGAAGCGCCCGACGCGATCCGC
GTGCATTTCCACGGAGCCGG

Downstream 100 bases:

>100_bases
CTTCGGGGCGACAGGACAAGCGAAAACGGATGCAGGAAACCGGCTACAGCCAAGGCGCGACGGCGCGACCCCGCCAGACC
GGCGGCATGCGCGCGCGCGG

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKLLPLIVIRPEPGNAATIAAARERGLHAIGYPLFRIEPTRWSVAEGRFEAILAGSANIFRHGGPQLDALKHLPVIAVGE
ATASAARAAGFTVVRTGEGGLQPVVETLAPGTYLRLAGEDRVTLAPPPGVRIETAVVYAARPVPLPDELVAVLARPAVVL
LHSGAAAKHFRQQCERTGITRESLYLACLAPRIAALAGDGWGDLRIADSRTDSDLLELGRRMCQTM

Sequences:

>Translated_226_residues
MKLLPLIVIRPEPGNAATIAAARERGLHAIGYPLFRIEPTRWSVAEGRFEAILAGSANIFRHGGPQLDALKHLPVIAVGE
ATASAARAAGFTVVRTGEGGLQPVVETLAPGTYLRLAGEDRVTLAPPPGVRIETAVVYAARPVPLPDELVAVLARPAVVL
LHSGAAAKHFRQQCERTGITRESLYLACLAPRIAALAGDGWGDLRIADSRTDSDLLELGRRMCQTM
>Mature_226_residues
MKLLPLIVIRPEPGNAATIAAARERGLHAIGYPLFRIEPTRWSVAEGRFEAILAGSANIFRHGGPQLDALKHLPVIAVGE
ATASAARAAGFTVVRTGEGGLQPVVETLAPGTYLRLAGEDRVTLAPPPGVRIETAVVYAARPVPLPDELVAVLARPAVVL
LHSGAAAKHFRQQCERTGITRESLYLACLAPRIAALAGDGWGDLRIADSRTDSDLLELGRRMCQTM

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 24016; Mature: 24016

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLPLIVIRPEPGNAATIAAARERGLHAIGYPLFRIEPTRWSVAEGRFEAILAGSANIF
CCCCEEEEEECCCCCEEEEHHHHHCCCEECCCEEEEECCCCCCCCCCCEEEEEECCCHHH
RHGGPQLDALKHLPVIAVGEATASAARAAGFTVVRTGEGGLQPVVETLAPGTYLRLAGED
HCCCCCHHHHHCCCEEEECCCHHHHHHHCCEEEEEECCCCHHHHHHHHCCCEEEEEECCC
RVTLAPPPGVRIETAVVYAARPVPLPDELVAVLARPAVVLLHSGAAAKHFRQQCERTGIT
CEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCC
RESLYLACLAPRIAALAGDGWGDLRIADSRTDSDLLELGRRMCQTM
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLPLIVIRPEPGNAATIAAARERGLHAIGYPLFRIEPTRWSVAEGRFEAILAGSANIF
CCCCEEEEEECCCCCEEEEHHHHHCCCEECCCEEEEECCCCCCCCCCCEEEEEECCCHHH
RHGGPQLDALKHLPVIAVGEATASAARAAGFTVVRTGEGGLQPVVETLAPGTYLRLAGED
HCCCCCHHHHHCCCEEEECCCHHHHHHHCCEEEEEECCCCHHHHHHHHCCCEEEEEECCC
RVTLAPPPGVRIETAVVYAARPVPLPDELVAVLARPAVVLLHSGAAAKHFRQQCERTGIT
CEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCC
RESLYLACLAPRIAALAGDGWGDLRIADSRTDSDLLELGRRMCQTM
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA