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The map label for this gene is kefBC [H]

Identifier: 87200704

GI number: 87200704

Start: 2931041

End: 2932786

Strand: Direct

Name: kefBC [H]

Synonym: Saro_2691

Alternate gene names: 87200704

Gene position: 2931041-2932786 (Clockwise)

Preceding gene: 87200700

Following gene: 87200714

Centisome position: 82.3

GC content: 66.21

Gene sequence:

>1746_bases
ATGGCCGAACATTCCTCACTGCTGCGCGACGGCTTCCTCCTCCTCGGCTTCGCGCTGATCTTCGTGCTGGTGTTCCGGCG
CCTGGGCCTTGGCGCGACGCTGGGCTATCTCCTTGCCGGCGCGGTCGTCGGCCCGCAGGTTCTGGGGCTGGTCGGCGATG
CGGAGAGCAAGCTGGGCATTGCGGAACTTGGCATCACGCTGCTGCTGTTCCTCGTGGGGCTGGAACTGAACCCTTCGCGG
CTGTGGCGGATGAAGCGCGACATCCTCGGCCTCGGCCTGTTGCAGGTGACCGCCTGCGGCCTCGCGGTAGCGGCGATGAT
CGGACTGACGACAGAGTTCAGTTGGGAAGCGGCGCTGGCGCTGGGCCTGCCACTGGCGCTTTCATCGACCGCGCAGGTGC
TGCCGATGCTCCAGTCCTCGGGAAGGCTGCGCACCCCGTTCGGGGAACGGGCCTTCGCGATCCTGCTGTTCCAGGACCTT
TCGATCATCCCGCTCATCACGATCATTTCCGCGATGAGCCGCAATCCGGCCGATGCGGGCGGACCTCCGGGCTGGCTGCT
TACGCTGTACACCCTGGCGGCGGTGGTTGCGCTGATCGCGGCGGGACGTTTCGTCATCAGGCCGTTGTTTCGCCTGATCG
GCAACCTTGGCGAACGCGAGATGTTCGTCGTGGCGGCGCTGTTCACGGTCATGGCATCGGCCGCAGTCATGGAAGCGCTG
GGCCTTTCCACCGCTCTCGGCGCGTTCGTGGCAGGCGTGATGCTGGCCGACAGCCCCTATCGCCACGAACTGGAAGCCGA
TGTCGAGCCGTTCCGTTCGATCCTGCTCGGCCTGTTCTTCCTGGCCGTGGGAATGATGCTGAACCTCCACGCCATTGCCG
AGCGGCCGCTGTTCGTGCTCGCCATGGCGGTGGGGCTGATCGCGATCAAGGCGGGAGCCATCTTCCTCATCGGTCTTGCC
TTCCGCATGACATGGCGAGGGGCGCTGGCGCTGGGCCTGCTGCTGAGCCAGGGCGGCGAGTTCGGGTTCGTGCTGTTCGC
GCAGGCCCAGAACGCGCTGCTGATCGCGCCCGATGCCGCCAGCCTGTTCGGCGCGATCGTGACGCTTTCGATGGCGACCA
CGCCCTTCCTGATGATGGCCACGCGCGGCATCCGCGAGGAAGCCGAGAGCCCGAAGGGCGAACGGGCTGGCCCCCAACCA
GATGGCGCGAACGCGATCATCGTCGGCTTCGGGCGCTTTGGCCAGGGCGTGAGCCAGATTCTGCTCGCCAGCAACATCCC
CGTCACCATGGTCGATACCGACATCGAGATGATCGACGTGGCGGCCGAATTCGGCGCGAAAGTCTATTTCGGCGATGGCA
CGCGCATCGACCTGCTGCGCCAGGCTGGCGCGGACGAGGCGGAGATGATCTTCTTCTGCATGGACGGCGATCAGATGTCG
CCCGACCTGGTCGAGGCAGTGCACGAAGCCTTCCCGCGCGCGGCGATCTATGTTCGCGCCTATGACCGGCGCGCGCTTAT
CCGCCTCAAGGAAACGCCTGCCAGCGCGGTGGTGCGCGAGGTTCTGGAATCGGCGGTGAAGATGGCGCGCATCGCGCTGC
ACGACGCCGGCCTCTCGGAAGAGGCGATCAACCGCGCCGAGGACATGTTCCGGGCACGCGACAAGGAACGGCTGAGGCTG
CAGGTCGAAGCGGGCGACGTGCGGGTGGCACGCGACAGGATCATCACCGAACCGTCTGGCTCATGA

Upstream 100 bases:

>100_bases
GGCGGCCGAGCCTGCCAGACCGGACGGATCTTCACCAGAGGCAGATCAACGCAGGCTGAACGGCGGTTGCGGCGCGATGC
GATAGGGCTAAACAGGAGGA

Downstream 100 bases:

>100_bases
CCGCAAGCCGCCGTGGGCAAGCCCGGCAAACTTCGGCGCCTGACCCGGTTGACTGCTTGGCCCAAACCGCGCATTAGCGC
GGTCGCACAGGGGCGGTTAG

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MAEHSSLLRDGFLLLGFALIFVLVFRRLGLGATLGYLLAGAVVGPQVLGLVGDAESKLGIAELGITLLLFLVGLELNPSR
LWRMKRDILGLGLLQVTACGLAVAAMIGLTTEFSWEAALALGLPLALSSTAQVLPMLQSSGRLRTPFGERAFAILLFQDL
SIIPLITIISAMSRNPADAGGPPGWLLTLYTLAAVVALIAAGRFVIRPLFRLIGNLGEREMFVVAALFTVMASAAVMEAL
GLSTALGAFVAGVMLADSPYRHELEADVEPFRSILLGLFFLAVGMMLNLHAIAERPLFVLAMAVGLIAIKAGAIFLIGLA
FRMTWRGALALGLLLSQGGEFGFVLFAQAQNALLIAPDAASLFGAIVTLSMATTPFLMMATRGIREEAESPKGERAGPQP
DGANAIIVGFGRFGQGVSQILLASNIPVTMVDTDIEMIDVAAEFGAKVYFGDGTRIDLLRQAGADEAEMIFFCMDGDQMS
PDLVEAVHEAFPRAAIYVRAYDRRALIRLKETPASAVVREVLESAVKMARIALHDAGLSEEAINRAEDMFRARDKERLRL
QVEAGDVRVARDRIITEPSGS

Sequences:

>Translated_581_residues
MAEHSSLLRDGFLLLGFALIFVLVFRRLGLGATLGYLLAGAVVGPQVLGLVGDAESKLGIAELGITLLLFLVGLELNPSR
LWRMKRDILGLGLLQVTACGLAVAAMIGLTTEFSWEAALALGLPLALSSTAQVLPMLQSSGRLRTPFGERAFAILLFQDL
SIIPLITIISAMSRNPADAGGPPGWLLTLYTLAAVVALIAAGRFVIRPLFRLIGNLGEREMFVVAALFTVMASAAVMEAL
GLSTALGAFVAGVMLADSPYRHELEADVEPFRSILLGLFFLAVGMMLNLHAIAERPLFVLAMAVGLIAIKAGAIFLIGLA
FRMTWRGALALGLLLSQGGEFGFVLFAQAQNALLIAPDAASLFGAIVTLSMATTPFLMMATRGIREEAESPKGERAGPQP
DGANAIIVGFGRFGQGVSQILLASNIPVTMVDTDIEMIDVAAEFGAKVYFGDGTRIDLLRQAGADEAEMIFFCMDGDQMS
PDLVEAVHEAFPRAAIYVRAYDRRALIRLKETPASAVVREVLESAVKMARIALHDAGLSEEAINRAEDMFRARDKERLRL
QVEAGDVRVARDRIITEPSGS
>Mature_580_residues
AEHSSLLRDGFLLLGFALIFVLVFRRLGLGATLGYLLAGAVVGPQVLGLVGDAESKLGIAELGITLLLFLVGLELNPSRL
WRMKRDILGLGLLQVTACGLAVAAMIGLTTEFSWEAALALGLPLALSSTAQVLPMLQSSGRLRTPFGERAFAILLFQDLS
IIPLITIISAMSRNPADAGGPPGWLLTLYTLAAVVALIAAGRFVIRPLFRLIGNLGEREMFVVAALFTVMASAAVMEALG
LSTALGAFVAGVMLADSPYRHELEADVEPFRSILLGLFFLAVGMMLNLHAIAERPLFVLAMAVGLIAIKAGAIFLIGLAF
RMTWRGALALGLLLSQGGEFGFVLFAQAQNALLIAPDAASLFGAIVTLSMATTPFLMMATRGIREEAESPKGERAGPQPD
GANAIIVGFGRFGQGVSQILLASNIPVTMVDTDIEMIDVAAEFGAKVYFGDGTRIDLLRQAGADEAEMIFFCMDGDQMSP
DLVEAVHEAFPRAAIYVRAYDRRALIRLKETPASAVVREVLESAVKMARIALHDAGLSEEAINRAEDMFRARDKERLRLQ
VEAGDVRVARDRIITEPSGS

Specific function: Transport system that facilitate potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=547, Percent_Identity=38.7568555758684, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1789749, Length=576, Percent_Identity=38.7152777777778, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786685, Length=538, Percent_Identity=27.8810408921933, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 62039; Mature: 61908

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHSSLLRDGFLLLGFALIFVLVFRRLGLGATLGYLLAGAVVGPQVLGLVGDAESKLGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCCCCCCCH
AELGITLLLFLVGLELNPSRLWRMKRDILGLGLLQVTACGLAVAAMIGLTTEFSWEAALA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LGLPLALSSTAQVLPMLQSSGRLRTPFGERAFAILLFQDLSIIPLITIISAMSRNPADAG
HCCCHHHCHHHHHHHHHHCCCCCCCCCCCHHEEEHHHHCCHHHHHHHHHHHHCCCCCCCC
GPPGWLLTLYTLAAVVALIAAGRFVIRPLFRLIGNLGEREMFVVAALFTVMASAAVMEAL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GLSTALGAFVAGVMLADSPYRHELEADVEPFRSILLGLFFLAVGMMLNLHAIAERPLFVL
HHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AMAVGLIAIKAGAIFLIGLAFRMTWRGALALGLLLSQGGEFGFVLFAQAQNALLIAPDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCHH
SLFGAIVTLSMATTPFLMMATRGIREEAESPKGERAGPQPDGANAIIVGFGRFGQGVSQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
LLASNIPVTMVDTDIEMIDVAAEFGAKVYFGDGTRIDLLRQAGADEAEMIFFCMDGDQMS
HHHCCCCEEEEECCHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCEEEEEEECCCCCC
PDLVEAVHEAFPRAAIYVRAYDRRALIRLKETPASAVVREVLESAVKMARIALHDAGLSE
HHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAINRAEDMFRARDKERLRLQVEAGDVRVARDRIITEPSGS
HHHHHHHHHHHHCCCCCEEEEEECCCEEEEHHHCCCCCCCC
>Mature Secondary Structure 
AEHSSLLRDGFLLLGFALIFVLVFRRLGLGATLGYLLAGAVVGPQVLGLVGDAESKLGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCCCCCCCH
AELGITLLLFLVGLELNPSRLWRMKRDILGLGLLQVTACGLAVAAMIGLTTEFSWEAALA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LGLPLALSSTAQVLPMLQSSGRLRTPFGERAFAILLFQDLSIIPLITIISAMSRNPADAG
HCCCHHHCHHHHHHHHHHCCCCCCCCCCCHHEEEHHHHCCHHHHHHHHHHHHCCCCCCCC
GPPGWLLTLYTLAAVVALIAAGRFVIRPLFRLIGNLGEREMFVVAALFTVMASAAVMEAL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GLSTALGAFVAGVMLADSPYRHELEADVEPFRSILLGLFFLAVGMMLNLHAIAERPLFVL
HHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AMAVGLIAIKAGAIFLIGLAFRMTWRGALALGLLLSQGGEFGFVLFAQAQNALLIAPDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCHH
SLFGAIVTLSMATTPFLMMATRGIREEAESPKGERAGPQPDGANAIIVGFGRFGQGVSQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
LLASNIPVTMVDTDIEMIDVAAEFGAKVYFGDGTRIDLLRQAGADEAEMIFFCMDGDQMS
HHHCCCCEEEEECCHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCEEEEEEECCCCCC
PDLVEAVHEAFPRAAIYVRAYDRRALIRLKETPASAVVREVLESAVKMARIALHDAGLSE
HHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAINRAEDMFRARDKERLRLQVEAGDVRVARDRIITEPSGS
HHHHHHHHHHHHCCCCCEEEEEECCCEEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]