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The map label for this gene is ilvE [H]

Identifier: 87200684

GI number: 87200684

Start: 2908711

End: 2909814

Strand: Direct

Name: ilvE [H]

Synonym: Saro_2671

Alternate gene names: 87200684

Gene position: 2908711-2909814 (Clockwise)

Preceding gene: 87200683

Following gene: 87200686

Centisome position: 81.67

GC content: 67.39

Gene sequence:

>1104_bases
ATGGCGAGCACCGCCGACACCACTGGCCTCACCTTCACCCGCAATCCGCACCCGGCACCGGTTGCTGCGGACGCGCGTGC
CCAGGTGCTGGCCAACCCCGGCTTCGGCACCACCTTCACCGATCACATGGTCGAGATCGACTACGCCGAGGGCCAGGGTT
GGCACGATGCGCGCGTCGTCCCTTATGGCCCGATCGCGCTCGATCCGGCGGCCGCCGTCCTGCACTATGCGCAGGAAATC
TTCGAAGGGCTCAAGGCCTACCGCCTTGCGGATGGCGGCATCGCGTTGTTCCGGCCCGAGGCGAATGCCCAGCGCTTCAA
CGCTTCGGCCCGCCGCCTTGCCATGCCCGAGCTGCCGGAGGATCTTTTCGTCGAGGCCGTGCGCCAGCAGGTGCTGGCCG
ACAAGGACTGGTTCCCCACGGTCGAAGGCGGATCGATGTACCTGCGCCCGTTCATGTTCGCGAGCGAGGCATTCCTCGGC
GTTCGCCCTGCACGGCAGTACAAGTTCATGGTCATTGCCAGCCCGGCCGGCAACTACTTCAAGTCCGGCGCACCGGCCGT
CTCGATCTGGGTGAGCGACTATACCCGCGCGGCGCCCGGCGGCACCGGCGCGGCCAAGTGCGGCGGCAACTACGCCGCCA
GCCTCGTCCCCACGGCCGAGGCGTTTTCGCGCGGGCATGACCAGGTCCTGTTCCTCGACGCTGCCGAACACAAGTGGGTC
GAGGAACTGGGGGGCATGAACCTGTTCTTCGTGTTCGACGACGGTTCGATCCTGACCCCGGAACTGACCGGCACGATCCT
ACCCGGCATCACCCGTTCCAGCCTGCTCACGCTTGCAGCGGAAGAAGGCCTGACCGTGCGCGAAGGCCGCTACAGCCTCG
ACCAGTGGAAGGCCGACGCCGCATCGGGCAAGCTCATCGAAACCTTTGCCTGCGGCACGGCGGCCGTCGTGACGCCCGTC
GGCAAGGTCGCCAGCCGCGATGGCGAGTTCACCATCGGCTCGGGTGGCCCCGGCCAGCTGACCCAGAAGCTGCGCCAGAA
GCTGGTAGGCATCCAGCGGGGCGAAATCGCCGATACCCACGGATGGGTCTCGCGCATCGCCTGA

Upstream 100 bases:

>100_bases
ACCGACGCGGCCCTTCACATTTATTACATTCCCCTTGCCTTTCACGCAATAATAGTTCACGGCGCTGCATCTCTGATTCT
AGCGCAAGGACTGCCTCCCC

Downstream 100 bases:

>100_bases
TGCCCCTCTGCCAAAGGCACGAAAAAGCCCGCCGCTCCTCAGGGAACGGCGGGCTTTTCAATGCTTGCAATATCAGAAGT
CGAACTGCGCGCGCATCCCG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MASTADTTGLTFTRNPHPAPVAADARAQVLANPGFGTTFTDHMVEIDYAEGQGWHDARVVPYGPIALDPAAAVLHYAQEI
FEGLKAYRLADGGIALFRPEANAQRFNASARRLAMPELPEDLFVEAVRQQVLADKDWFPTVEGGSMYLRPFMFASEAFLG
VRPARQYKFMVIASPAGNYFKSGAPAVSIWVSDYTRAAPGGTGAAKCGGNYAASLVPTAEAFSRGHDQVLFLDAAEHKWV
EELGGMNLFFVFDDGSILTPELTGTILPGITRSSLLTLAAEEGLTVREGRYSLDQWKADAASGKLIETFACGTAAVVTPV
GKVASRDGEFTIGSGGPGQLTQKLRQKLVGIQRGEIADTHGWVSRIA

Sequences:

>Translated_367_residues
MASTADTTGLTFTRNPHPAPVAADARAQVLANPGFGTTFTDHMVEIDYAEGQGWHDARVVPYGPIALDPAAAVLHYAQEI
FEGLKAYRLADGGIALFRPEANAQRFNASARRLAMPELPEDLFVEAVRQQVLADKDWFPTVEGGSMYLRPFMFASEAFLG
VRPARQYKFMVIASPAGNYFKSGAPAVSIWVSDYTRAAPGGTGAAKCGGNYAASLVPTAEAFSRGHDQVLFLDAAEHKWV
EELGGMNLFFVFDDGSILTPELTGTILPGITRSSLLTLAAEEGLTVREGRYSLDQWKADAASGKLIETFACGTAAVVTPV
GKVASRDGEFTIGSGGPGQLTQKLRQKLVGIQRGEIADTHGWVSRIA
>Mature_366_residues
ASTADTTGLTFTRNPHPAPVAADARAQVLANPGFGTTFTDHMVEIDYAEGQGWHDARVVPYGPIALDPAAAVLHYAQEIF
EGLKAYRLADGGIALFRPEANAQRFNASARRLAMPELPEDLFVEAVRQQVLADKDWFPTVEGGSMYLRPFMFASEAFLGV
RPARQYKFMVIASPAGNYFKSGAPAVSIWVSDYTRAAPGGTGAAKCGGNYAASLVPTAEAFSRGHDQVLFLDAAEHKWVE
ELGGMNLFFVFDDGSILTPELTGTILPGITRSSLLTLAAEEGLTVREGRYSLDQWKADAASGKLIETFACGTAAVVTPVG
KVASRDGEFTIGSGGPGQLTQKLRQKLVGIQRGEIADTHGWVSRIA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010904, Length=332, Percent_Identity=38.2530120481928, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI296010906, Length=332, Percent_Identity=38.2530120481928, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI38176287, Length=332, Percent_Identity=38.2530120481928, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI50658084, Length=364, Percent_Identity=35.989010989011, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI296010902, Length=332, Percent_Identity=33.1325301204819, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI296010900, Length=332, Percent_Identity=33.1325301204819, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI258614015, Length=295, Percent_Identity=36.271186440678, Blast_Score=168, Evalue=8e-42,
Organism=Escherichia coli, GI48994963, Length=319, Percent_Identity=32.9153605015674, Blast_Score=139, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17568601, Length=346, Percent_Identity=36.9942196531792, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17565728, Length=339, Percent_Identity=34.5132743362832, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322002, Length=375, Percent_Identity=37.0666666666667, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322608, Length=346, Percent_Identity=37.5722543352601, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24641779, Length=338, Percent_Identity=37.5739644970414, Blast_Score=219, Evalue=3e-57,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 39274; Mature: 39143

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTADTTGLTFTRNPHPAPVAADARAQVLANPGFGTTFTDHMVEIDYAEGQGWHDARVV
CCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEE
PYGPIALDPAAAVLHYAQEIFEGLKAYRLADGGIALFRPEANAQRFNASARRLAMPELPE
ECCCCEECHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCHHHHCCHHHHCCCCCCCH
DLFVEAVRQQVLADKDWFPTVEGGSMYLRPFMFASEAFLGVRPARQYKFMVIASPAGNYF
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
KSGAPAVSIWVSDYTRAAPGGTGAAKCGGNYAASLVPTAEAFSRGHDQVLFLDAAEHKWV
HCCCCEEEEEECCCCCCCCCCCCCHHCCCCEEEEECCCHHHHHCCCCEEEEEECHHHHHH
EELGGMNLFFVFDDGSILTPELTGTILPGITRSSLLTLAAEEGLTVREGRYSLDQWKADA
HHHCCCEEEEEECCCCEECCCCCCCCCCCCCHHHHEEEHHCCCCEEECCCCCHHHHHCCC
ASGKLIETFACGTAAVVTPVGKVASRDGEFTIGSGGPGQLTQKLRQKLVGIQRGEIADTH
CCCCEEEECCCCCHHHHHCHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHH
GWVSRIA
HHHHHCC
>Mature Secondary Structure 
ASTADTTGLTFTRNPHPAPVAADARAQVLANPGFGTTFTDHMVEIDYAEGQGWHDARVV
CCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEE
PYGPIALDPAAAVLHYAQEIFEGLKAYRLADGGIALFRPEANAQRFNASARRLAMPELPE
ECCCCEECHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCHHHHCCHHHHCCCCCCCH
DLFVEAVRQQVLADKDWFPTVEGGSMYLRPFMFASEAFLGVRPARQYKFMVIASPAGNYF
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
KSGAPAVSIWVSDYTRAAPGGTGAAKCGGNYAASLVPTAEAFSRGHDQVLFLDAAEHKWV
HCCCCEEEEEECCCCCCCCCCCCCHHCCCCEEEEECCCHHHHHCCCCEEEEEECHHHHHH
EELGGMNLFFVFDDGSILTPELTGTILPGITRSSLLTLAAEEGLTVREGRYSLDQWKADA
HHHCCCEEEEEECCCCEECCCCCCCCCCCCCHHHHEEEHHCCCCEEECCCCCHHHHHCCC
ASGKLIETFACGTAAVVTPVGKVASRDGEFTIGSGGPGQLTQKLRQKLVGIQRGEIADTH
CCCCEEEECCCCCHHHHHCHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHH
GWVSRIA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]