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The map label for this gene is glpD

Identifier: 87200455

GI number: 87200455

Start: 2627754

End: 2629262

Strand: Reverse

Name: glpD

Synonym: Saro_2442

Alternate gene names: 87200455

Gene position: 2629262-2627754 (Counterclockwise)

Preceding gene: 87200456

Following gene: 87200454

Centisome position: 73.82

GC content: 66.8

Gene sequence:

>1509_bases
GTGGACGGGAAGGATGAGGTCGGCAACCGACGCGTATTCGACGTCGCCGTCATCGGCGGCGGCGTCAACGGCTGCGGCAT
CGCCCGCGATGCCGCAGGACGCGGGGCAAGTGTGCTGCTGCTCGAGGCCAACGACCTCGCGAGCGGCACCTCGTCCAATT
CCAGCAAGCTCATCCACGGCGGCCTGCGCTATCTCGAACACTACGAGTTCGGCCTCGTGCGCGAAGCGCTGTCTGAGCGC
GAGAAGCTGTGGGCCATCGCGCCGCACATCATCTGGCCGATGCGTTTCGTACTGCCGTGGGTGCGGGGCCTGCGTCCGCG
CTGGCTTTTGCGGACCGGCCTGTTTCTTTACGATCATATCGGCGCGCGCAAGCTTTTGCCCGCGACCGAGACGATCCGGC
TGGACCGCCACCCGGCGGGCCGGCCGCTGAAGCCCGAGTTCGTGCACGGTTTCGTCTATTCGGATGGATGGGTGGACGAT
GCGAGGCTCGTGGTGCTGAATGCGCGCGATGCGGCGAACCGGGGGGCGGAGGTGCGTACGCGCTGTCCCGTCACGGCGCT
GCGGCGTGAGGACGACCTGTGGTCGATCGAAACCGCGCACGGTCGGTTCCTCGCGCGCTCGGTCATAAACGCGGCGGGAC
CCTCCGTGCTTGCCATCCTGGGTTGCAGCGGCGAGCCGCCCAGGCAGTCGATCCGGCTGGTGCGCGGGTCGCACATCGTG
GTGCGCAAGCTGTTCGATCATCCGCACCCCTATTTCTTCCAGCTTCCTGACGGCCGCATTTTCTTCGCTATCCCCTATGA
GCACGACTTCACCCTGATCGGCACCACCGACCGCGACCACCGGCCCGGCGATCCGATCGAGGCGAGCGCGGAGGAGATCG
CCTATCTCTGCGAAGGGGCGAGCCGCTTCTTCAGAAAGCCGGTCGTGCCGGCCGACGTGGTGTGGACCTATGCCGGCGTT
CGCCCGTTGGTGGACGACGGCTCGGGCAAGCCGGAGGCGGCGACGCGCGGCTATCGCTTCGACATCAGCGACGAGAACGA
AGGCGCGCCGATCCTCTCCGTGTTCGGCGGGAAGATCACGACCTACCGCACCCTGTCCCAGGAAGCGGTCGACCGCATGG
CCACGCGCATTCCCGCGCTGGAAGGCAGGCACTGGACAGACAATAGCGCCTTGCCTGGCGGGGATTTCGGCGTGAACGAG
GTCGACCGGCTGATCGCCGATTTGCGCGGGCGCTATCCGTTCCTCGAACCTGCCTGGGCGGACAGGCTGGTGCGGTCCTA
CGGCACGCTGGCCTTTCTCGTTCTTGGCGAGGCGCATACGCTGAACGACTGTGGCCGCCATTTCGGCCACGGACTTACCG
AGCGGGAGGTTCGCTACCTCCTCGCCAACGAATGGGCGAGAGAGGCCGGGGACGTGCTTTGGCGGCGGACCAAGCTGGGC
CTGCGGCTGGACGCGGCGGAGCAGGCCGACCTGGCGCAATTCATGAAAGCGAACCTGCCCAATGACTGA

Upstream 100 bases:

>100_bases
CTGTCGGGTTATCCGCATGCGCAGGAAGCCGACATGTTCGCCCGCTACGTCCTGCCGCACATCAACCACGGACCGTTGAA
CATCTGAAGGAGGCAGGGCC

Downstream 100 bases:

>100_bases
CGAGCGCCGCATCCTTGTTCTCGACGAAGGAACGACCTCGACCCGTGCGATCCTCTATTCCGCGCGAGGCGAGGTGCTGG
GCTGTGCGCAGGAAGAACTG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MDGKDEVGNRRVFDVAVIGGGVNGCGIARDAAGRGASVLLLEANDLASGTSSNSSKLIHGGLRYLEHYEFGLVREALSER
EKLWAIAPHIIWPMRFVLPWVRGLRPRWLLRTGLFLYDHIGARKLLPATETIRLDRHPAGRPLKPEFVHGFVYSDGWVDD
ARLVVLNARDAANRGAEVRTRCPVTALRREDDLWSIETAHGRFLARSVINAAGPSVLAILGCSGEPPRQSIRLVRGSHIV
VRKLFDHPHPYFFQLPDGRIFFAIPYEHDFTLIGTTDRDHRPGDPIEASAEEIAYLCEGASRFFRKPVVPADVVWTYAGV
RPLVDDGSGKPEAATRGYRFDISDENEGAPILSVFGGKITTYRTLSQEAVDRMATRIPALEGRHWTDNSALPGGDFGVNE
VDRLIADLRGRYPFLEPAWADRLVRSYGTLAFLVLGEAHTLNDCGRHFGHGLTEREVRYLLANEWAREAGDVLWRRTKLG
LRLDAAEQADLAQFMKANLPND

Sequences:

>Translated_502_residues
MDGKDEVGNRRVFDVAVIGGGVNGCGIARDAAGRGASVLLLEANDLASGTSSNSSKLIHGGLRYLEHYEFGLVREALSER
EKLWAIAPHIIWPMRFVLPWVRGLRPRWLLRTGLFLYDHIGARKLLPATETIRLDRHPAGRPLKPEFVHGFVYSDGWVDD
ARLVVLNARDAANRGAEVRTRCPVTALRREDDLWSIETAHGRFLARSVINAAGPSVLAILGCSGEPPRQSIRLVRGSHIV
VRKLFDHPHPYFFQLPDGRIFFAIPYEHDFTLIGTTDRDHRPGDPIEASAEEIAYLCEGASRFFRKPVVPADVVWTYAGV
RPLVDDGSGKPEAATRGYRFDISDENEGAPILSVFGGKITTYRTLSQEAVDRMATRIPALEGRHWTDNSALPGGDFGVNE
VDRLIADLRGRYPFLEPAWADRLVRSYGTLAFLVLGEAHTLNDCGRHFGHGLTEREVRYLLANEWAREAGDVLWRRTKLG
LRLDAAEQADLAQFMKANLPND
>Mature_502_residues
MDGKDEVGNRRVFDVAVIGGGVNGCGIARDAAGRGASVLLLEANDLASGTSSNSSKLIHGGLRYLEHYEFGLVREALSER
EKLWAIAPHIIWPMRFVLPWVRGLRPRWLLRTGLFLYDHIGARKLLPATETIRLDRHPAGRPLKPEFVHGFVYSDGWVDD
ARLVVLNARDAANRGAEVRTRCPVTALRREDDLWSIETAHGRFLARSVINAAGPSVLAILGCSGEPPRQSIRLVRGSHIV
VRKLFDHPHPYFFQLPDGRIFFAIPYEHDFTLIGTTDRDHRPGDPIEASAEEIAYLCEGASRFFRKPVVPADVVWTYAGV
RPLVDDGSGKPEAATRGYRFDISDENEGAPILSVFGGKITTYRTLSQEAVDRMATRIPALEGRHWTDNSALPGGDFGVNE
VDRLIADLRGRYPFLEPAWADRLVRSYGTLAFLVLGEAHTLNDCGRHFGHGLTEREVRYLLANEWAREAGDVLWRRTKLG
LRLDAAEQADLAQFMKANLPND

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=523, Percent_Identity=31.1663479923518, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI285002231, Length=523, Percent_Identity=31.1663479923518, Blast_Score=170, Evalue=4e-42,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=48.0769230769231, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1788574, Length=492, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115534726, Length=516, Percent_Identity=29.8449612403101, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17509253, Length=511, Percent_Identity=29.3542074363992, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322036, Length=565, Percent_Identity=29.2035398230088, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI161077125, Length=514, Percent_Identity=28.5992217898833, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24653942, Length=514, Percent_Identity=28.5992217898833, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24653944, Length=514, Percent_Identity=28.5992217898833, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI20130025, Length=514, Percent_Identity=28.5992217898833, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24586295, Length=458, Percent_Identity=26.6375545851528, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921278, Length=520, Percent_Identity=24.8076923076923, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55922; Mature: 55922

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGKDEVGNRRVFDVAVIGGGVNGCGIARDAAGRGASVLLLEANDLASGTSSNSSKLIHG
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHH
GLRYLEHYEFGLVREALSEREKLWAIAPHIIWPMRFVLPWVRGLRPRWLLRTGLFLYDHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GARKLLPATETIRLDRHPAGRPLKPEFVHGFVYSDGWVDDARLVVLNARDAANRGAEVRT
CCHHCCCCCCEEEECCCCCCCCCCHHHEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEE
RCPVTALRREDDLWSIETAHGRFLARSVINAAGPSVLAILGCSGEPPRQSIRLVRGSHIV
CCCHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCHHH
VRKLFDHPHPYFFQLPDGRIFFAIPYEHDFTLIGTTDRDHRPGDPIEASAEEIAYLCEGA
HHHHHCCCCCEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
SRFFRKPVVPADVVWTYAGVRPLVDDGSGKPEAATRGYRFDISDENEGAPILSVFGGKIT
HHHHHCCCCCHHHHHHHCCCCEECCCCCCCCCHHCCCEEEECCCCCCCCCEEEECCCCEE
TYRTLSQEAVDRMATRIPALEGRHWTDNSALPGGDFGVNEVDRLIADLRGRYPFLEPAWA
EEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
DRLVRSYGTLAFLVLGEAHTLNDCGRHFGHGLTEREVRYLLANEWAREAGDVLWRRTKLG
HHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LRLDAAEQADLAQFMKANLPND
EEECCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDGKDEVGNRRVFDVAVIGGGVNGCGIARDAAGRGASVLLLEANDLASGTSSNSSKLIHG
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHH
GLRYLEHYEFGLVREALSEREKLWAIAPHIIWPMRFVLPWVRGLRPRWLLRTGLFLYDHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GARKLLPATETIRLDRHPAGRPLKPEFVHGFVYSDGWVDDARLVVLNARDAANRGAEVRT
CCHHCCCCCCEEEECCCCCCCCCCHHHEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEE
RCPVTALRREDDLWSIETAHGRFLARSVINAAGPSVLAILGCSGEPPRQSIRLVRGSHIV
CCCHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCHHH
VRKLFDHPHPYFFQLPDGRIFFAIPYEHDFTLIGTTDRDHRPGDPIEASAEEIAYLCEGA
HHHHHCCCCCEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
SRFFRKPVVPADVVWTYAGVRPLVDDGSGKPEAATRGYRFDISDENEGAPILSVFGGKIT
HHHHHCCCCCHHHHHHHCCCCEECCCCCCCCCHHCCCEEEECCCCCCCCCEEEECCCCEE
TYRTLSQEAVDRMATRIPALEGRHWTDNSALPGGDFGVNEVDRLIADLRGRYPFLEPAWA
EEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
DRLVRSYGTLAFLVLGEAHTLNDCGRHFGHGLTEREVRYLLANEWAREAGDVLWRRTKLG
HHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LRLDAAEQADLAQFMKANLPND
EEECCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]